ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help

|
|
|
|

Trending News

Guarding Against the Dangers of Vitamin D Deficiency

Omega-3 fatty acids, vitamin D may control brain serotonin, affecting behavior and psychiatric disor...

How Glutathione Can Save Your Life

Fatigue & Fibro Fog: Could You Have a B-12 Deficiency?

New Dietary Guidelines Reverse Flawed Recommendations on Cholesterol

Long term antibiotic therapy may be an effective treatment for children co-morbid with Lyme disease ...

Anticancer Properties Of Saffron

Beyond Depression... SAMe Broad-Spectrum Protection Against Disorders Of Aging

BPA exposure linked to autism spectrum disorder, study reports

Omega-3 Fatty Acids Appear to Protect Damaged Heart After Heart Attack

 
Print Page
Email Article

Nutritional and herbal supplements for anxiety and anxiety-related disorders: Systematic review – Source: Nutrition Journal, Oct 7, 2010

  [ 15 votes ]   [ Discuss This Article ]
By Shaheen E Lakhan, Karen F Vieira • www.ProHealth.com • October 22, 2010


[Note: to read the full text & tables of this review of clinical trials testing herbal / nutritional supplements as support for relief of anxiety disorders, click here.]

Background: Over the past several decades, complementary and alternative medications have increasingly become a part of everyday treatment. With the rising cost of prescription medications and their production of unwanted side effects, patients are exploring herbal and other natural remedies for the management and treatment of psychological conditions.

Psychological disorders are one of the most frequent conditions seen by clinicians, and often require a long-term regimen of prescription medications. Approximately 6.8 million Americans suffer from generalized anxiety disorder.

Many also suffer from the spectrum of behavioral and physical side effects that often accompany its treatment. It is not surprising that there is universal interest in finding effective natural anxiolytic (anti-anxiety) treatments with a lower risk of adverse effects or withdrawal.

Methods: An electronic and manual search was performed through MEDLINE/PubMed and EBSCO. Articles were not discriminated by date of publication. Available clinical studies published in English that used human participants and examined the anxiolytic potential of dietary and herbal supplements were included. Data were extracted and compiled into tables that included the study design, sample population, intervention, control, length of treatment, outcomes, direction of evidence, and reported adverse events.

Results: A total of 24 studies that investigated five different CAM monotherapies and eight different combination treatments and involved 2,619 participants met the inclusion criteria and were analyzed. There were 21 randomized controlled trials and three open-label, uncontrolled observational studies.

Most studies involved patients who had been diagnosed with either an anxiety disorder or depression (n = 1786). However, eight studies used healthy volunteers (n = 877) who had normal levels of anxiety, were undergoing surgery, tested at the upper limit of the normal range of a trait anxiety scale, had adverse premenstrual symptoms or were peri-menopausal, reported anxiety and insomnia, or had one month or more of elevated generalized anxiety.

Heterogeneity and the small number of studies for each supplement or combination therapy prevented a formal meta-analysis.

Of the randomized controlled trials reviewed, 71% (15 out of 21) showed a positive direction of evidence.

Any reported side effects were mild to moderate.

Conclusions: Based on the available evidence, it appears that nutritional and herbal supplementation is an effective method for treating anxiety and anxiety-related conditions without the risk of serious side effects.

There is the possibility that any positive effects seen could be due to a placebo effect, which may have a significant psychological impact on participants with mental disorders.

However, based on this systematic review:

• Strong evidence exists for the use of herbal supplements containing extracts of passionflower or kava and combinations of [amino acids] L-lysine and L-arginine as treatments for anxiety symptoms and disorders.

Magnesium-containing supplements, and other herbal combinations may hold promise, but more research is needed before these products can be recommended to patients.

• St. John's wort monotherapy has insufficient evidence for use as an effective anxiolytic treatment.

Source: Nutrition Journal, Oct 7, 2010;9:42. PMID: 20929532, by Lakhan SE, Vieira KF. Global Neuroscience Initiative Foundation, Los Angeles, California, USA. [Email: slakhan@gnif.org]
 




Please Discuss This Article:   Post a Comment 



[ Be the first to comment on this article ]




 
Free Chronic Fatigue Syndrome and Fibromyalgia Newsletters
Subscribe to
Our FREE
Newsletter
Subscribe Now!
Receive up-to-date ME/CFS & Fibromyalgia treatment and research news
 Privacy Guaranteed  |  View Archives

Save on Vitamins and Supplements

Featured Products

Magnesium Plus Magnesium Plus
Natural mineral for nerve & muscle function
Amino Acid Complex™ Amino Acid Complex™
Quickly-absorbed Building Blocks for a Stronger body
L-Theanine Calm-Plex with GABA & 5-HTP (Suntheanine®) by ProHealth L-Theanine Calm-Plex with GABA & 5-HTP (Suntheanine®) by ProHealth
Synergistic Formula Enhances Mood & Well-being
FibroSleep™ by ProHealth FibroSleep™ by ProHealth
The All-in-One Natural Sleep Aid

Natural Remedies

D-ficient? Health Risks You Need to Know About D-ficient? Health Risks You Need to Know About
Cocoa's Polyphenol Riches – All the Health Benefits without the Sugar, Calories and Guilt Cocoa's Polyphenol Riches – All the Health Benefits without the Sugar, Calories and Guilt
Secret Nutrient for Radiant Skin Secret Nutrient for Radiant Skin
Coenzyme Q10 - The Energy Maker Coenzyme Q10 - The Energy Maker
The Remarkable Benefits of Reishi Medicinal Mushrooms The Remarkable Benefits of Reishi Medicinal Mushrooms

FIBROMYALGIA RESOURCES
What is Fibromyalgia?
Fibromyalgia Diagnosis
Fibromyalgia Symptoms
Fibromyalgia Treatments
| CFS RESOURCES
What is CFS?
ME/CFS Diagnosis
ME/CFS Symptoms
ME/CFS Treatments
| FORUMS
Fibromyalgia
ME/CFS
ADVANCED MEDICAL LABS
WHOLESALE  |  AFFILIATES
GUARANTEE  |  PRIVACY
CONTACT US
LIBRARY
RSS
SITE MAP
ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus
Credit Card Processing