ProHealth health Vitamin and Natural Supplement Store and Health
Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help

|
|
|
|

Trending News

Missing protein explains link between obesity, diabetes

Fish oil use associated with brain volume preservation

The Brain Boosting and Fatigue Fighting B-12

Genetic basis for distinct type of autism uncovered

Unsuspected aspect of immune regulation revealed: Role of B cells

IBS, Crohn’s Disease, Colitis, and Other Digestive Disorders

Explaining 'Healthy' Obesity

Sinus Congestion and Sinusitis, Healing Naturally

In the gut, immunity is a two-way street

Omega 3 Fatty Acids Lessen Severity of Osteoarthritis in Mice

 
Print Page
Email Article

Study Describes Why Herpes Viruses Reactivate to Cause Disease

  [ 25 votes ]   [ Discuss This Article ]
www.ProHealth.com • November 4, 2012


The work of researchers at Ohio State and Oxford Universities suggests the T-cells responsible for controlling a herpes virus can reduce significantly during times of new infection, allowing the latent virus to reactivate.

The mere mention of the word "herpes" usually conjures negative images and stereotypes, but most people have been infected with some form of the virus.

For most, a sore, pustules or rash appears, heals and is forgotten, although the virus remains latent just waiting for the right circumstances to come back (from shingles to cold sores). Intracellular reactivations of old herpes virus infections such as cytomegalovirus and Epstein-Barr are thought to trigger or contribute to the symptoms of a large percentage of fibromyalgia and ME/CFS patients.

Now, the mystery behind what triggers herpes viruses to become active again is closer to being solved thanks to a study reported in the November issue of Journal of Leukocyte Biology.

In the report, the researchers show how the immune system may lose its control over the virus when facing new microbial threats, such as when it must fend off other viral invaders or bacteria.

"Because almost all people are infected by one or more herpes family viruses during their lifetime, the potential impact of these findings is significant," says co-author Charles H. Cook, MD, director of surgical critical care at Ohio State College of Medicine. "We hope that by understanding how these latent viral infections are controlled we can prevent reactivation events and improve people's lives."

To make this discovery, the researchers studied mice with latent cytomegalovirus (CMV) during severe bacterial infections.

They found that:

Memory T-cells responsible for CMV control were reduced significantly during a new infection with bacteria.

• This, in effect, reduced the "brakes" which kept the virus under control, allowing the virus to reactivate and cause disease. In humans, CMV reactivations typically cause ‘flu-like’ symptoms.  

• When the immune system eventually sensed the reactivation, the memory T-cell levels returned to normal, effectively restoring the body's control over the virus.

"Finding ways to control herpes flare ups is important, not only for the health of the person with the virus, but also for preventing its transmission," comments John Wherry, PhD, Deputy Editor of the Journal of Leukocyte Biology.

The Importance of 'Microbial Interplay'

"This report highlights the important interplay when we are 'co-infected' with more than one microbe,” Dr. Wherry emphasizes, “and provides important insights into why the immune system sometimes fails, as well as how it can regain control of latent herpes virus infections."

___

Source: Based on Federation of American Societies for Experimental Biology news release, Oct 31, 2012




Discuss This Article Post a Comment 




[ Be the first to comment on this article ]




 
Free Chronic Fatigue Syndrome and Fibromyalgia Newsletters
Subscribe to
Our FREE
Newsletter
Subscribe Now!
Receive up-to-date ME/CFS & Fibromyalgia treatment and research news
 Privacy Guaranteed  |  View Archives

Featured Products

Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Optimized Curcumin Longvida® by ProHealth Optimized Curcumin Longvida® by ProHealth
Supports Cognition, Memory & Overall Health
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
Vitamin D3 Extreme™ by ProHealth Vitamin D3 Extreme™ by ProHealth
50,000 IU Vitamin D3 - Prescription Strength

Natural Remedies

The Big Blue Fish that Helps Chase the Blues Away The Big Blue Fish that Helps Chase the Blues Away
The Brain Boosting and Fatigue Fighting B-12 The Brain Boosting and Fatigue Fighting B-12
Natural Support for Mood, Sleep and Mental Focus? L-theanine Natural Support for Mood, Sleep and Mental Focus? L-theanine
Ubiquinol - A More Advanced Form of the Energy Producing Nutrient CoQ-10 Ubiquinol - A More Advanced Form of the Energy Producing Nutrient CoQ-10
IBS, Crohn’s Disease, Colitis, and Other Digestive Disorders IBS, Crohn’s Disease, Colitis, and Other Digestive Disorders

FIBROMYALGIA RESOURCES
What is Fibromyalgia?
Fibromyalgia 101
Fibromyalgia Symptoms
Fibromyalgia Treatments
| CFS RESOURCES
What is CFS?
ME/CFS 101
ME/CFS Symptoms
ME/CFS Treatments
| FORUMS
Fibromyalgia
ME/CFS
ADVANCED MEDICAL LABS
WHOLESALE  |  AFFILIATES
GUARANTEE
CONTACT US
PRIVACY
RSS
SITE MAP
ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus
Credit Card Processing