Activate Now
 
ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Acupuncture used in clinical settings reduced symptoms of menopause

Benefits of Coconut Oil Are Undeniable

How Awesome Is Ashwagandha?

CoQ10 supplementation associated with lower pro-inflammatory factors in randomized trial

SURVEY RESULTS: Should Opioids Be Restricted for Chronic Illness?

Clinical trial demonstrates success of low FODMAP diet

Research Demonstrates Superiority of Krill Oil Compared to Fish Oil

Vitamin nicotinamide riboside protects mice from diabetes complications

What’s so Remarkable About Rosemary?

Vitamin-mineral supplement prevents brain cell loss in recent research

 
Print Page
Email Article

CFS Patients with POTS: Clinically Distinct Subgroup

  [ 448 votes ]   [ Discuss This Article ]
www.ProHealth.com • December 6, 2012


Article:
Clinical characteristics of a novel subgroup of chronic fatigue syndrome patients with postural orthostatic tachycardia syndrome
– Source: Journal of Internal Medicine, Dec 4, 2012

By I Lewis, J Newton, et al.

[Note: POTS is one of five types of orthostatic intolerance that collectively affect nearly all chronic fatigue syndrome (ME/CFS) patients, according to Dr. David Bell - see “Orthostatic Intolerance and Chronic Fatigue Syndrome.”]

Abstract:
Objectives: A significant proportion of patients with chronic fatigue syndrome (CFS) also have postural orthostatic tachycardia syndrome (POTS). We aimed to characterize these patients and differentiate them from CFS patients without POTS in terms of clinical and autonomic features.

Methods: A total of 179 patients with CFS (1994 Centers for Disease Control and Prevention criteria) attending one of the largest Department of Health-funded CFS clinical services were included in the study.

Outcome measures were:

1. Symptom assessment tools including the fatigue impact scale, Chalder fatigue scale, Epworth sleepiness scale (ESS), orthostatic grading scale (OGS) and hospital anxiety and depression scale (HADS-A and -D, respectively),

2. Autonomic function analysis including heart rate variability and

3. Hemodynamic responses including left ventricular ejection time and systolic blood pressure drop upon standing.

Results:

CFS patients with POTS (13%, n=24) were:

• Younger (29 +/- 12 vs. 42 +/- 13 years, P<0.0001) [probability the difference resulted by chance less than 1 in 10,000],

• Less fatigued (Chalder fatigue scale, 8 +/- 4 vs. 10 +/- 2, P=0.002),

• Less depressed (HADS-D, 6 +/- 4 vs. 9 +/- 4, P=0.01),

• And had reduced daytime hypersomnolence [hypersomnolence is excessive sleeping/sleepiness] (ESS, 7 +/- 6 vs. 10 +/- 5, P=0.02)…

…Compared with patients without POTS.

In addition, they exhibited greater orthostatic intolerance (OGS, 11 +/- 5; P<0.0001) and autonomic dysfunction.

A combined clinical assessment tool of Epworth sleepiness scale 9 or less and orthostatic grading scale 9 or more identifies accurately CFS patients with POTS with 100% positive and negative predictive values.

Conclusions:

The presence of POTS marks a distinct clinical group of CFS patents, with phenotypic features differentiating them from those without POTS.

A combination of validated clinical assessment tools can determine which CFS patients have POTS with a high degree of accuracy, and thus potentially identify those who require further investigation and consideration for therapy to control heart rate.

Source: Journal of Internal Medicine, Dec 4, 2012. PMID:23206180, by Lewis I, Pairman J, Spickett G, Newton JL. Institute for Ageing & Health, Newcastle University, Newcastle, UK. [Email: julia.newton@ncl.ac.uk]





Post a Comment

Featured Products From the ProHealth Store
Vitamin D3 Extreme™ Ultra EPA  - Fish Oil Ultra ATP+, Double Strength

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products


Article Comments



Be the first to comment on this article!

Post a Comment


 
All Natural Deodorants

Featured Products

Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength
Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%

Natural Remedies

SAD? Coping with Seasonal Affective Disorder
Help for Soreness and Swelling: What Do Silkworms Have to Do With It? Help for Soreness and Swelling: What Do Silkworms Have to Do With It?
Looking for Energy? Turn to Plants. Looking for Energy? Turn to Plants.
Astaxanthin - A Little-Known but Power-Packed Nutrient Astaxanthin - A Little-Known but Power-Packed Nutrient
The Big Blue Fish that Helps Chase the Blues Away The Big Blue Fish that Helps Chase the Blues Away

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler

· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE AND SAVE 15% NOW*
Be the first to know about new products, special discounts and the latest health news. *New subscribers only

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2016 ProHealth, Inc. All rights reserved. Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map