ProHealth health Vitamin and Natural Supplement Store and Health
Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help

|
|
|
|
 
Print Page
Email Article

How Chronic Fatigue Syndrome Patients Respond to Flu Vaccine

  [ 14 votes ]   [ 1 Comment ]
www.ProHealth.com • January 28, 2013

previous article next article

[Note: You may read the full text of this article free HERE.]

Article: 

Humoral and cellular immune responses after influenza vaccination in patients with chronic fatigue syndrome
– Source: BMC Immunology, December 17, 2012

By Hetty Prinsen, et al.

Abstract:


Background:
Chronic fatigue syndrome (CFS) is a clinical condition characterized by severe and disabling fatigue that is medically unexplained and lasts longer than 6 months. Although it is possible to effectively treat CFS, the nature of the underlying physiology remains unclear. Various studies have sought evidence for an underlying disturbance in immunity. The aim of this study was to compare the humoral [relating to the part of the immune response that involves antibodies secreted by B cells and circulating in bodily fluids] and cellular immune responses upon influenza vaccination in CFS patients and healthy controls.

Results:
Identical antibody titers were observed in CFS patients and healthy controls. Patients and controls demonstrated similar seroprotection rates against all three virus-strains of the influenza vaccine, both pre- and post-vaccination. Functional T cell reactivity was observed in both CFS patients and healthy controls. CFS patients showed a non-significant, numerically lower cellular proliferation at baseline compared to controls. Vaccination induced a significant increase in cellular proliferation in CFS patients, but not in healthy controls. Cytokine production and the number of regulatory T cells were comparable in patients and controls.

Conclusions:
The humoral and cellular immune responses upon influenza vaccination were comparable in CFS patients and healthy controls. Putative aberrations in immune responses in CFS patients were not evident for immunity towards influenza. Standard seasonal influenza vaccination is thus justified and, when indicated, should be recommended for patients suffering from CFS.


Source:
BMC Immunology, December 17, 2012. By Hetty Prinsen, I Jolanda M. deVries, Ruurd Torensma, Jeanette M. Pots, Sasja F. Mulder, Carla M.L. Van Herpen, Lammy D. Elving, Gijs Bleijenberg, Foekje F. Stelma and Hanneke W. M. van Laarhoven. Department of Medical Oncology, Radboud University Nijmegen Medical Centre, Geert Grooteplein Zuid 8, 6525, GA, Nijmegen, the Netherlands; Department of Tumor Immunology, Radboud University Nijmegen Medical Centre, Nijmegen, the Netherlands; Department of General Internal Medicine, Radboud University Nijmegen Medical Centre, Nijmegen, the Netherlands; Expert Centre for Chronic Fatigue, Radboud University Nijmegen Medical Centre, Nijmegen, the Netherlands; Department of Medical Microbiology, Radboud University Nijmegen Medical Centre, Nijmegen, the Netherlands; Department of Medical Oncology, Academic Medical Center University of Amsterdam, Amsterdam, the Netherlands.



previous article
  Rating 3.4 (14 votes) next article




DISCUSS THIS ARTICLE   (1 existing comment) Post a Comment 


yes, but...
Posted by: Sandy10m
Mar 20, 2013
That's great news that the flu vaccine might have the same effect on the antibodies, but what about the number of patients that actually got the flu from the flu shot? I'm one of those people who almost always gets the flu after the shot. And it takes a really long time for my arm to recover. CFS patients have notoriously funky immune systems, overreacting to normal stuff like foods and scents, and not reacting at all to colds and flu (getting sick all the time). We need information about THAT and what to do about it. I'm trying the low-dose Naltrexone to mediate my immune system, and it's working very well so far.
Reply Reply
 
Free Chronic Fatigue Syndrome and Fibromyalgia Newsletters
Subscribe to
Our FREE
Newsletter
Subscribe Now!
Receive up-to-date ME/CFS & Fibromyalgia treatment and research news
 Privacy Guaranteed  |  View Archives

Save on Your Next Order

Featured Products
Vitamin D3 5000 IU Vitamin D3 5000 IU
Give your body a boost with the sunshine vitamin
Natural Resveratrol Natural Resveratrol
Powerful Antioxidant Support + Positive Anti-aging Effects
FibroSleep™ by ProHealth FibroSleep™ by ProHealth
The All-in-One Natural Sleep Aid
Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength
Omega 3-6-9 Omega 3-6-9
All three EFAs in one convenient form

Most Viewed Articles
What's the Hidden Cause Behind YOUR Fibromyalgia Flares? [more]

Pridgen Reports Fibromyalgia Antiviral Trial Results “Very Positive”: Predicts New Approach Will Be ... [more]

How to Limit or Minimize Your Fibromyalgia Flare [more]

VIDEO: IACFS/ME Conference - Summary of Research by Dr. Komaroff [more]

Mitochondrial Dysfunction, Post-Exertional Malaise and CFS/ME [more]

The Devil Is In The Details – A Herpes Simplex Virus Inquiry For Fibromyalgia and Chronic Fatigue Sy... [more]

Sympathetic Nervous System Dysfunction in FIbromyalgia and Overlapping Conditions [more]

Review of Nutritional Supplements Used for ME/CFS and FM [more]

FREE: Stop Feeding Yourself PAIN Guide [more]

Sympathetic nervous system dysfunction in fibromyalgia, chronic fatigue syndrome, irritable bowel sy... [more]


FIBROMYALGIA RESOURCES
What is Fibromyalgia?
Fibromyalgia 101
Fibromyalgia Symptoms
Fibromyalgia Treatments
| CFS RESOURCES
What is CFS?
ME/CFS 101
ME/CFS Symptoms
ME/CFS Treatments
| FORUMS
Fibromyalgia
ME/CFS
ADVANCED MEDICAL LABS
WHOLESALE  |  AFFILIATES
GUARANTEE
CONTACT US
PRIVACY
RSS
SITE MAP
ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus
Credit Card Processing