ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help

Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Delayed diagnosis of Lyme disease has devastating effect on patients

Association of lyme disease and schizoaffective disorder, bipolar type: Is it inflammation mediated?

Adapt to Stress Naturally with These Power Herbs

A short-term Borrelia burgdorferi infection model identifies tissue tropisms and bloodstream surviva...

Curcumin Made 65X More Bioavailable - Modern Take on a "Golden" Spice Busts Brain Fog, Joint & Body ...

Why So Many Arthritis Sufferers Fail to Find Relief

Discovering Coffee's Unique Health Benefits

Safely Manage Joint Inflammation: Curcumin

Bay Area Lyme Foundation Awards Grant to Harvard Medical School Researchers for Development of an Ac...

New Research Substantiates the Anti-Aging Properties of DHEA

 
Print Page
Email Article

Brain-Derived Neurotrophic Factor Correlates with Depression Intensity in Fibromyalgia Patients

  [ Not Yet Rated ]   [ Discuss This Article ]
www.ProHealth.com • February 9, 2013


[Note: Brain-derived neurotrophic factor (BDNF) is a protein that is a member of the neurotrophin family of growth factors.  It acts on certain types of nerve cells, enabling them to grow and survive.  It is primarily located in the central nervous system, where it acts on cells in the brain and the eye.]

Article:

Serum level of brain-derived neurotrophic factor in fibromyalgia syndrome correlates with depression but not anxiety.
– Source: Neurochemistry International, January 11, 2013

By B. Nugraha, C. Korallus and C. Gutenbrunner

Abstract:

Brain-derived neurotrophic factor (BDNF) has been known to play a role in fibromyalgia syndrome (FMS) patients. Depression and anxiety are quite common additional symptoms in FMS. However the role of BDNF in these symptoms still needs to be elucidated. Although BDNF has been shown to be relevant in major depression, however studies could not show such differences between FMS patients with and without major depression.

As mood-related symptom occurs frequently and differs in its intensity in FMS patients, BDNF level should be measured in subgroup regarding depression and anxiety scale. Therefore the aim of this study was to evaluate the correlation of BDNF in serum of FMS with intensity of depression and anxiety. Additionally, interleukin (IL)-6 was measured.

  • This study showed that serum level of BDNF was age-dependent in Hcs [healthy controls].

  • FMS patients had higher level of serum BDNF as compared to HC.

  • Additionally, serum level of BDNF showed correlation with depression, but not with anxiety.

  • Serum level of BDNF increased with depression score in FMS.

  • However, serum level of IL-6 was not correlated with both depression and anxiety scores.

Taken together, BDNF is involved in the pathophysiology of FMS. Additionally, it seems to be correlated with intensity of depressive symptoms in FMS.


Source: Neurochemistry International, January 11, 2013. By B. Nugraha, C. Korallus and C. Gutenbrunner. Deparment of Rehabilitation Medicine, Hannover Medical School, Hannover, Germany; Deparment of Chemistry, University of Indonesia, Depok, Indonesia. Electronic address: Nugraha.Boya@mh-hannover.de.




Please Discuss This Article:   Post a Comment 



[ Be the first to comment on this article ]




 
Free Chronic Fatigue Syndrome and Fibromyalgia Newsletters
Subscribe to
Our FREE
Newsletter
Subscribe Now!
Receive up-to-date ME/CFS & Fibromyalgia treatment and research news
 Privacy Guaranteed  |  View Archives

Save on Vitamins and Supplements

Featured Products

Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid

Natural Remedies

When a Good Night's Sleep Is Just a Daydream... When a Good Night's Sleep Is Just a Daydream...
Irritable Bowel Syndrome: Unlocking the Secrets of Peppermint, Acacia and Fennel Irritable Bowel Syndrome: Unlocking the Secrets of Peppermint, Acacia and Fennel
Can Glycine + Amino Acids Be the Secret to Deep, Rejuvenating Sleep? Can Glycine + Amino Acids Be the Secret to Deep, Rejuvenating Sleep?
Cell-Charging Compound Gives Steady Energy to Fibromyalgia & Chronic Fatigue Patients Cell-Charging Compound Gives Steady Energy to Fibromyalgia & Chronic Fatigue Patients
Everything You Always Wanted to Know About Sleep But Were Too Tired to Ask Everything You Always Wanted to Know About Sleep But Were Too Tired to Ask

FIBROMYALGIA RESOURCES
What is Fibromyalgia?
Fibromyalgia Diagnosis
Fibromyalgia Symptoms
Fibromyalgia Treatments
| CFS RESOURCES
What is CFS?
ME/CFS Diagnosis
ME/CFS Symptoms
ME/CFS Treatments
| FORUMS
Fibromyalgia
ME/CFS
ADVANCED MEDICAL LABS
WHOLESALE  |  AFFILIATES
GUARANTEE  |  PRIVACY
CONTACT US
LIBRARY
RSS
SITE MAP
ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus
Credit Card Processing