Activate Now
 
ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help

Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Social Anxiety Disorder Linked to High Serotonin Levels, Throwing Treatment with SSRIs into Serious ...

Therapeutic Effects and Mechanisms of Action of Rifaximin in Gastrointestinal Diseases

Promoting Optimal Nutrition with Digestive Enzymes

Immune response to a flu vaccine yields new insights into narcolepsy

Omega-3 supplements and antioxidants may help with preclinical Alzheimer's disease

Children with Lyme Disease

Health Benefits of Ginseng

7-Keto DHEA The Fat-Burning Metabolite of DHEA

Intestinal Pseudoobstruction Caused by Chronic Lyme Neuroborreliosis. A Case Report

Nutritional Strategies for Preventing Age-Related Vision Loss

 
Print Page
Email Article

Study Shows Combination of Drugs Effective Treatment for Fibromyalgia (FM)

  [ 71 votes ]   [ Discuss This Article ]
www.ProHealth.com • September 19, 2001


A recent scientific study has shown the medication cyclobenzaprine when combined with antidepressant medications is an effective treatment for Fibromyalgia (FM) when antidepressants alone do not lead to a reduction in FM symptoms. This was according to an abstract published in the September 2001 supplement of the Journal of Musculoskeletal Pain.

Researchers at the Private Pain Clinic and Hospital Samaritano in Sao Paulo, Brazil found that cyclobenzaprine, due to its central action for muscle relaxation, in combination with antidepressants, leads to a more restful sleep, eliminates muscle spasms, and consequently eliminates widespread pain. This combination also produced little to no side effects.

The study included 73 patients, all of who fulfilled the 1990 ACR criteria for FM. Fifty-seven women and 18 men with an age range of 18 to 83 were treated with antidepressants such as, amitriptyline, fluoxetine and venlafaxine, in standard dosages. After a period of 7 to 63 months all patients reported feeling much improved, however still complained of an unpleasant sleep, widespread pain and muscle spasms.

Cyclobenzaprine was then added to the basic medication regimen while trying to avoid side effects. All other supporting treatments such as psychological therapy, exercise, stretching, active trigger point inactivation, postural conditioning, and acupuncture were also maintained. A numerical rating scale was used to subjectively evaluate pain and quality of sleep at each patient’s return appointment.

At the first return appointment 24 patients reported a 50% increase in relief, 31 reported an improvement between 60% and 70%, 12 patients reported an improvement of 80% or more, and 6 patients reported no change. Two patients reported obstipation (severe and obstinate constipation) and one complained of dry mouth and tachycardia (relatively rapid heart action). After a follow up of 12.5 months the results of the cyclobenzaprine and antidepressant combination continued to be noticed, leading the researchers to maintain the procedure, and to begin treatment with this combination but with reduced doses of antidepressants.


Please Discuss This Article:   Post a Comment 



[ Be the first to comment on this article ]




 
Free Chronic Fatigue Syndrome and Fibromyalgia Newsletters
Subscribe to
Our FREE
Newsletter
Subscribe Now!
Receive up-to-date ME/CFS & Fibromyalgia treatment and research news
 Privacy Guaranteed  |  View Archives

Save on Nutritional Supplement Orders

Featured Products

Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils

Natural Remedies

Sleep Like a Baby in Nature's Cradle Sleep Like a Baby in Nature's Cradle
Anti-Inflammatory Properties of Tart Cherry Anti-Inflammatory Properties of Tart Cherry
Itching to Find Dry Skin Relief? Itching to Find Dry Skin Relief?
Front Line Defense Against Colds & Flu - Support for Healthy Immune System Balance Front Line Defense Against Colds & Flu - Support for Healthy Immune System Balance
Prepare Yourself for Cold & Flu Season

FIBROMYALGIA RESOURCES
What is Fibromyalgia?
Fibromyalgia Diagnosis
Fibromyalgia Symptoms
Fibromyalgia Treatments
| CFS RESOURCES
What is CFS?
ME/CFS Diagnosis
ME/CFS Symptoms
ME/CFS Treatments
| FORUMS
Fibromyalgia
ME/CFS
ADVANCED MEDICAL LABS
WHOLESALE  |  AFFILIATES
GUARANTEE  |  PRIVACY
CONTACT US
LIBRARY
RSS
SITE MAP
ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus
Credit Card Processing