ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Is a Good Night's Sleep at the Top of Your Wishlist?

Ashwagandha Helps Hormones - Aids Arthritis

Why You Should Be Eating More Porcini Mushrooms

A Breathalyzer for Disease?

How Bacopa Can Help Improve Your Cognitive Function

Magnesium Reduces Diabetes and Helps Keep You Young

Lavender Aromatherapy Can Ease Pre-Op Anxiety

Give Your Health a Much-Needed Boost With Geranium

The Role of Resveratrol in Achieving Optimal Health

Could Coconut Oil Help Reduce Antibiotics?

 
Print Page
Email Article

Cytokines across the night in chronic fatigue syndrome with and without Fibromyalgia - Source: Clinical and Vaccine Immunology, Feb 24, 2010

  [ 11 votes ]   [ Discuss This Article ]
By Toru Nakamura, Benjamin H. Natelson, et al. • www.ProHealth.com • March 11, 2010


The symptoms of chronic fatigue syndrome are consistent with cytokine dysregulation. [Cytokines are cell-to-cell 'signaling molecules' secreted by immune cells.] This has led to the hypothesis of immune dysregulation as the cause of this illness.

To further test this hypothesis, we did repeated blood sampling for cytokines while patients and matched healthy controls slept in the sleep lab.

Because no one method for assaying cytokines is acknowledged to be better than another, we assayed for protein in serum, message in peripheral blood lymphocytes (PBLs) and function in resting and stimulated PBLs

• We found no evidence of pro-inflammatory cytokine upregulation.

• Instead, in line with some of our earlier studies, we did find some evidence to support a role for an increase in IL-10 (Interleukin-10), an anti-inflammatory cytokine.

Although the changes were small, they may contribute to the common complaint of CFS patients of disrupted sleep.

Source: Clinical and Vaccine Immunology, Feb 24, 2010;03-11. PMID: 20181767 Nakamura T, Schwander SK, Donnelly R, Ortega F, Togo F, Broderick G, Yamamoto Y, Cherniack NS, Rapoport D, Natelson BH. Pain & Fatigue Study Center, and Departments of Neurosciences and Medicine, UMDNJ-New Jersey Medical School, Newark NJ; Department of Work Stress Control, Japan National Institute of Occupational Safety and Health, Kawasaki, Japan; Department of Medicine, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Canada; Educational Physiology Laboratory, Graduate School of Education, The University of Tokyo; Department of Medicine, Division of Pulmonary and Critical Care Medicine, NYU School of Medicine, New York, New York, USA. [Email: natelsbe@umdnj.edu]





Post a Comment

Featured Products From the ProHealth Store
Optimized Curcumin Longvida® Energy NADH™ 12.5mg Ultra ATP+, Double Strength


Article Comments



Be the first to comment on this article!

Post a Comment


 
Optimized Curcumin Longvida with Omega-3

Featured Products

Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%

Natural Remedies

Top 3 Nutrients to Detox the Liver and Soothe Digestion Top 3 Nutrients to Detox the Liver and Soothe Digestion
The Genetic Mutation That May Compromise Your Health - And What to Do About It The Genetic Mutation That May Compromise Your Health - And What to Do About It
Block Acid Reflux to Prevent Esophageal Problems! Block Acid Reflux to Prevent Esophageal Problems!
Carry a Massage Therapist in Your Pocket Carry a Massage Therapist in Your Pocket
Strontium - The Missing Mineral for Strong Bones Strontium - The Missing Mineral for Strong Bones

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map