ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

SURVEY: Weight Management & Chronic Illness

Japanese green tea consumers have reduced risk of dementia

Do Nothing, Accomplish Everything! The Connection Between Breathing and Healing

Meet the ProHealth Editors

Best Herbs to Help With Insomnia

Choline: Why You Should Eat Your Egg Yolks and Take Krill

Calcium, vitamin D supplementation associated improved stroke recovery

Acupressure reduced fatigue in breast cancer survivors

More positive evidence for melatonin in breast cancer battle

Omega-3 shows promise as stroke treatment

 
Print Page
Email Article

Treating Bacterial Infections Can Help Asthmatics

  [ 58 votes ]   [ Discuss This Article ]
www.ProHealth.com • June 24, 2002




A new study indicates that many patients with asthma may have bacterial infections in their lungs, and that treatment with antibiotics can improve their ability to breathe. Researchers at National Jewish Medical and Research Center report in the June issue of the journal Chest>/i> that 31 of 55 chronic, stable asthmatics showed evidence of infection with mycoplasma or chlamydia bacteria. After six weeks of treatment with the antibiotic clarithromycin, these patients demonstrated clinically significant improvements in their lung function.

"We believe that antibiotics may become an important addition to the therapeutic options for some patients with asthma," said Richard Martin, M.D., Professor of Medicine at National Jewish and co-author of the paper. "However, diagnosis of chlamydia or mycoplasma infection requires an invasive procedure. At the present time only select centers can appropriately perform the necessary tests. We are working on simpler methods to make the diagnosis easier."

The researchers took multiple tissue samples from the upper and lower airways of 55 adults with mild to moderate asthma. They looked for evidence of bacterial infections by culturing tissue samples and performing genetic analyses. None of the tissue cultures grew any bacteria, but DNA from Mycoplasma pneumoniae or Chlamydia pneumoniae were detected in samples from 31 of the 55, or 56%, of the patients.

Before antibiotic treatment began, there were no significant differences in lung function between those showing evidence of bacterial infection and those showing none. Lung function was evaluated by measuring the amount of air patients could exhale in one second, called forced expiratory volume in one second or FEV1.

Twenty-six of the patients then took 500 milligrams of the antibiotic clarithromycin twice a day for six weeks while continuing their standard asthma medications. Twenty-six other asthma patients continued their standard asthma medications and a placebo instead of the antibiotic treatment. Three patients were excluded from the treatment analysis due to scheduling and compliance problems.

Patients with no evidence of bacterial infection who were randomized to the antibiotic group showed no significant change in their lung function after treatment. The lung function of patients with evidence of bacterial infection, however, improved after the antibiotic treatment. Their average FEV1 rose 200 milliliters.

"That is a clinically significant improvement," said co-author Monica Kraft, M.D., Associate Professor of Medicine at National Jewish. "Those patients noticed an improvement in their breathing ability."

It is not clear how a bacterial infection influences chronic asthma. There is evidence that it can exacerbate existing asthma. But the National Jewish researchers also believe that it may contribute to the development of the disease. They are currently conducting experiments in mice to better understand the role of bacterial infections in asthma.

Although the clarithromycin did improve lung function in mild to moderate asthmatics with evidence of bacterial infections, Drs. Martin and Kraft do not advocate its widespread use for asthma. When properly used, standard asthma medications can control symptoms in the vast majority of asthma patients. Overuse of antibiotics in general has led to an increase in drug-resistant bacteria around the world.

The antibiotic helped only those who showed evidence of bacterial infections.

Detection of bacterial infection requires invasive procedures, such as bronchoscopy, that are difficult to perform, unpleasant for the patient, and pose slight hazards themselves. But for patients who do not achieve control of their asthma even with maximum doses of standard medications, Dr. Martin believes physicians should consider evaluating their patients for bacterial infections and treating with antibiotics if the lungs do appear infected.

National Jewish is a nonprofit, nonsectarian institution dedicated to the research, treatment and prevention of respiratory, allergic and immune system diseases.

Chest is a peer-reviewed journal published by the American College of Chest Physicians. It is available online each month at www.chestjournal.org. ACCP represents more than 15,000 members who provide clinical, respiratory, and cardiothoracic patient care in the U.S. and throughout the world. ACCP's mission is to promote the prevention and treatment of diseases of the chest through leadership, education, research and communication.





Post a Comment

Featured Products From the ProHealth Store
Ultra ATP+, Double Strength Vitamin D3 Extreme™ FibroSleep™

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products


Article Comments



Be the first to comment on this article!

Post a Comment


 
Natural Pain Relief Supplements

Featured Products

Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function

Natural Remedies

The Remarkable Benefits of Reishi Medicinal Mushrooms The Remarkable Benefits of Reishi Medicinal Mushrooms
D-ficient? Health Risks You Need to Know About D-ficient? Health Risks You Need to Know About
More Weight Loss than Any Other Discovery in Supplement History More Weight Loss than Any Other Discovery in Supplement History
Front Line Defense Against Colds & Flu - Support for Healthy Immune System Balance Front Line Defense Against Colds & Flu - Support for Healthy Immune System Balance
Block food Cravings At Their Molecular Root Block food Cravings At Their Molecular Root

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE AND SAVE 15% NOW*
Be the first to know about new products, special discounts and the latest health news. *New subscribers only

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2016 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map