ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help

|
|
|
|

Trending News

Strengthening DNA to Prevent Inflammation, Heart Disease, Dementia and More

Magnesium: Widespread Deficiency with Deadly Consequences

Turmeric compound boosts regeneration of brain stem cells

CoQ10: The Longevity Factor

Culprits of Autism Identified: Toxins, Gut Bacteria, Nutritional Deficiencies, and Vaccines Made wit...

Omega-3 Fatty Acids Increase Brain Volume

Optimal Prostate Defense Requires a Multi-Modal Strategy

Use of Broad-Spectrum Antibiotics Before Age 2 Associated with Obesity Risk

Extending Life and Fighting Disease with Resveratrol

How Lipoic Acid Preserves Critical Mitochondrial Function

 
Print Page
Email Article

Growth hormone as concomitant treatment in severe Fibromyalgia associated with low IGF-1 serum levels. A pilot study - Source: BMC Musculoskeletal Disorders, Nov 30, 2007

  [ 108 votes ]   [ 1 Comment ]
By Guillem Cuatrecasas, MD, et al. • www.ProHealth.com • December 8, 2007


[Note: The full text of this article is available free of charge at http://www.biomedcentral.com/content/pdf/1471-2474-8-119.pdf ]

Background: There is evidence of functional growth hormone (GH) deficiency, expressed by means of low insulin-like growth factor 1 (IGF-1) serum levels, in a subset of fibromyalgia patients. The efficacy of GH versus placebo has been previously suggested in this population. We investigated the efficacy and safety of low dose GH as an adjunct to standard therapy in the treatment of severe, prolonged and well-treated fibromyalgia patients with low IGF-1 levels.

Methods: Twenty-four patients were enrolled in a randomized, open-label, best available care-controlled study. Patients were randomly assigned to receive either 0.0125 mg/kg/d of GH subcutaneously (titrated depending on IGF-1) added to standard therapy or standard therapy alone during one year. The number of tender points, the Fibromyalgia Impact Questionnaire (FIQ) and the EuroQol 5D (EQ-5D), including a Quality of Life visual analogic scale (EQ-VAS) were assessed at different time-points.

Results:

  • At the end of the study, the GH group showed a 60% reduction in the mean number of tender points (pairs) compared to the control group (p<0.05; 3.25+/-0.8 vs. 8.25+/-0.9).
  • Similar improvements were observed in FIQ score (p<0.05) and EQ-VAS scale (p<0.001).
  • There was a prompt response to GH administration, with most patients showing improvement within the first months in most of the outcomes.
  • The concomitant administration of GH and standard therapy was well tolerated, and no patients discontinued the study due to adverse events.
  • Conclusions: The present findings indicate the advantage of adding a daily GH dose to the standard therapy in a subset of severe fibromyalgia patients with low IGF-1 serum levels.

    Trial Registration: NCT00497562 (ClinicalTrials.gov).

    Source: BMC Musculoskeletal Disorders. 2007 Nov 30;8(1):119 [E-pub ahead of print] PMID: 18053120, by Cuatrecasas G, Riudavets C, Guell MA, Nadal A. Servicio de Endocrinología, Centro Médico Teknon, Barcelona, Spain. [E-mail: Guillem Cuatrecasas, MD, endocrinologia@teknon.es]




    Please Discuss This Article:   Post a Comment 

    Growth Hormone Study
    Posted by: brighteyestish
    Dec 19, 2007
    I was in a 6 month study with a oral growth hormone and It did very well. It took 3-4 months before I started to stop hurting. At the end of the study My tender points not longer hurt...AT ALL. Now that I am off of it I feel sluggish and drained. I hope they put it on the market.
    Reply Reply
     
    Free Chronic Fatigue Syndrome and Fibromyalgia Newsletters
    Subscribe to
    Our FREE
    Newsletter
    Subscribe Now!
    Receive up-to-date ME/CFS & Fibromyalgia treatment and research news
     Privacy Guaranteed  |  View Archives

    Save on Vitamins and Supplements

    Featured Products

    Energy NADH™ 12.5mg Energy NADH™ 12.5mg
    Improve Energy & Cognitive Function
    FibroSleep™ by ProHealth FibroSleep™ by ProHealth
    The All-in-One Natural Sleep Aid
    Optimized Curcumin Longvida® by ProHealth Optimized Curcumin Longvida® by ProHealth
    Supports Cognition, Memory & Overall Health
    Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
    Reduce Fatigue up to 45%
    Ultra ATP+, Double Strength Ultra ATP+, Double Strength
    Get energized with malic acid & magnesium

    Natural Remedies

    The Big Blue Fish that Helps Chase the Blues Away The Big Blue Fish that Helps Chase the Blues Away
    Reversing Neurodegeneration with a New Magnesium Compound Reversing Neurodegeneration with a New Magnesium Compound
    Itching to Find Dry Skin Relief? Itching to Find Dry Skin Relief?
    Research Links Green Tea to Weight Loss Research Links Green Tea to Weight Loss
    Dreaming of a Good Night's Sleep? Dreaming of a Good Night's Sleep?

    FIBROMYALGIA RESOURCES
    What is Fibromyalgia?
    Fibromyalgia 101
    Fibromyalgia Symptoms
    Fibromyalgia Treatments
    | CFS RESOURCES
    What is CFS?
    ME/CFS 101
    ME/CFS Symptoms
    ME/CFS Treatments
    | FORUMS
    Fibromyalgia
    ME/CFS
    ADVANCED MEDICAL LABS
    WHOLESALE  |  AFFILIATES
    GUARANTEE
    CONTACT US
    PRIVACY
    RSS
    SITE MAP
    ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus
    Credit Card Processing