ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help

|
|
|
|

Trending News

New Option For Chronic Fatigue Syndrome

The Most Powerful Natural Antioxidant Discovered to Date - Hydroxytyrosol

How Lipoic Acid Preserves Critical Mitochondrial Function

Living Longer, Healthier Lives with Resveratrol

Iodine: The Forgotten Medicine

Stop Bacteria With Nature's Antibiotics

Lipoic Acid Reverses Mitochondrial Decay

Nutraceutical Update - Rhodiola

Strengthen Cell Function with Energy-Boosting Niagen

Coenzyme Q10 Helps Veterans Battle Gulf War Illness Symptoms

 
Print Page
Email Article

EU Equivalent of FDA Declines to Recommend Cymbalta as Therapy for Fibromyalgia

  [ 3 votes ]   [ Discuss This Article ]
www.ProHealth.com • October 24, 2008


Oct 23, 2008: Cymbalta/Xeristar - the second drug to receive FDA approval for treatment of fibromyalgia - has not been recommended for treatment of FM in Europe. The Committee for Medicinal Products for Human Use, which advises the European Medicines Agency on approvals of drugs for community-wide marketing authorization, has issued a negative opinion on this indication.

Cymbalta/Xeristar has been approved since 2004 in the EU for treatment of major depression, pain of diabetic peripheral neuropathy, and generalized anxiety disorder, and under other names has been approved as a therapy for stress urinary incontinence.

The drug is believed to work by raising levels of the neurotransmitters serotonin and noradrenaline in the spinal cord and brain (by blocking their re-uptake), thereby supporting cell-to-cell communication. These neurotransmitters are thought to play a role in fibromyalgia, and trials of Cymbalta/Xeristar have focused on measuring improvement of FM symptoms with a focus on pain, in patients with and without depression.

The CHMP expressed concern that the improvement demonstrated in FM trials was modest, might be owing to the drug's effect on mood, and as such did not outweigh the drug's risks. It suggested that a long-term placebo controlled trial would be needed.

The drug's makers have the opportunity to request a re-examination of the opinion, and have not indicated plans for a long-term controlled trial in the EU.



Please Discuss This Article:   Post a Comment 



[ Be the first to comment on this article ]




 
Free Chronic Fatigue Syndrome and Fibromyalgia Newsletters
Subscribe to
Our FREE
Newsletter
Subscribe Now!
Receive up-to-date ME/CFS & Fibromyalgia treatment and research news
 Privacy Guaranteed  |  View Archives

Save on Immune Support Supplements

Featured Products

Optimized Curcumin Longvida® by ProHealth Optimized Curcumin Longvida® by ProHealth
Supports Cognition, Memory & Overall Health
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Vitamin D3 Extreme™ by ProHealth Vitamin D3 Extreme™ by ProHealth
50,000 IU Vitamin D3 - Prescription Strength
FibroSleep™ by ProHealth FibroSleep™ by ProHealth
The All-in-One Natural Sleep Aid

Natural Remedies

Broad Spectrum Protection Against Brain Aging Broad Spectrum Protection Against Brain Aging
Running on Empty? Fuel Up with NADH Running on Empty? Fuel Up with NADH
Front Line Defense Against Colds & Flu - Support for Healthy Immune System Balance Front Line Defense Against Colds & Flu - Support for Healthy Immune System Balance
IBS, Crohn’s Disease, Colitis, and Other Digestive Disorders IBS, Crohn’s Disease, Colitis, and Other Digestive Disorders
Research Links Green Tea to Weight Loss Research Links Green Tea to Weight Loss

FIBROMYALGIA RESOURCES
What is Fibromyalgia?
Fibromyalgia 101
Fibromyalgia Symptoms
Fibromyalgia Treatments
| CFS RESOURCES
What is CFS?
ME/CFS 101
ME/CFS Symptoms
ME/CFS Treatments
| FORUMS
Fibromyalgia
ME/CFS
ADVANCED MEDICAL LABS
WHOLESALE  |  AFFILIATES
GUARANTEE
CONTACT US
PRIVACY
RSS
SITE MAP
ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus
Credit Card Processing