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Intravenous lidocaine for fibromyalgia syndrome: An open trial - Source: Journal of Rheumatology, online Mar 5, 2009

  [ 21 votes ]   [ 1 Comment ]
By M Schafranski, et al. • • March 8, 2009

[Note: Lidocaine (aka xylocaine) is commonly used as a local anesthetic or numbing agent – most often in dental work and minor surgery.]

Fibromyalgia is a disorder characterized by chronic widespread pain. In this study, we investigated the effect of intravenous infusions of lidocaine in pain and quality of life of patients with fibromyalgia.

Twenty-three consecutive patients were included in the study, which consisted on five sequential intravenous 2% lidocaine infusions with rising dosages (2-5 mg/kg, days 1-5).

Fibromyalgia Impact Questionnaire (FIQ), Health Assessment Questionnaire, and a visual analog scale (VAS) for pain were applied before the first lidocaine infusion, immediately after the fifth infusion, and 30 days after the fifth infusion.

A significant improvement was observed in the FIQ scores after the fifth infusion (73.52 +/- 16.56 vs 63.29 +/- 21.21, p = 0.02), which was maintained after 30 days (73.52 +/- 16.56 vs 63.85 +/- 24.59, p = 0.04).

Similar results were seen concerning the VAS: 8.19 +/- 1.76 vs 6.84 +/- 2.44, p = 0.01 and 8.19 +/- 1.76 vs 7.17 +/- 2.35, p = 0.05, respectively.

Intravenous lidocaine infusions are safe and effective in the management of fibromyalgia.

Source: Journal of Rheumatology, online Mar 5, 2009. PMID: 19263182, by Schafranski MD, Malucelli T, Machado F, Takeshi H, Kaiber F, Schmidt C, Harth F. Department of Rheumatology, Santa Casa de Misericórdia, Ponta Grossa, PR, Brazil. []

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Article Comments Post a Comment

Trigger point injections with Lidocaine
Posted by: pjt127
Mar 18, 2009
I have not tried the intravenous lidocaine infusions but I have done serveral trigger point injections using lidocaine, saline solution and a bit of steriods and they work great! Especially if you follow it up with physicial therapy and use the laser that heats up the muscle under your skin. I have had FM since 1990 and this combination is great. I can actually move my left arm/shoulder without pain. Another thing that works for me when the pain meds cannot handle the pain is a cream called Sombra. I hope this helps someone out there.
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