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Neuropsychological functioning of U.S. Gulf War veterans 10 years after the war – Source: Journal of the International Neuropsychological Society, Sep 2009

  [ 30 votes ]   [ 1 Comment ]
By Rosemary Toomy, et al. • • August 27, 2009

Many U.S. Gulf War-era veterans complained of poor cognition following the war. This study assessed neuropsychological functioning in veterans 10 years after the war through objective tests.

2,189 Gulf War-era veterans (1,061 deployed, 1,128 non-deployed) were examined at 1 of 16 U.S. Veterans Affairs medical centers. Outcomes included neuropsychological domains derived from factor analysis and individual test scores.

Deployed veterans performed significantly worse than non-deployed veterans:

• On 2 of 8 factors (motor speed & sustained attention, analysis not corrected for multiple comparisons)

• And on 4 of 27 individual test variables (Trails A & B, California Verbal Learning Test-List B, and Continuous Performance Test sensitivity, with only Trails B surviving Bonferroni correction).

Within deployed veterans:

• Khamisiyah exposure [site where rockets were destroyed and the nerve agent Sarin, which is similar in mechanism of action and biological activity to some commonly used insecticides and medicines, was released into the air] was negatively correlated with motor speed after controlling for emotional distress. [More sarin exposure, slower motor speed.]

• Depressive symptoms and self-reported exposure to toxicants were independently and significantly associated with worse sustained attention.

• Other factors were also associated with self-reported exposures.

• The findings were not a result of differential effort across groups.

Gulf War deployment is associated with subtle declines of motor speed and sustained attention, despite overall intact neuropsychological functioning.

Evidence suggests that toxicant exposures influence both these functions, and depressive symptoms also influence attention.

Source: Journal of the International Neuropsychological Society, Sep 2009;15(5):717-29. PMID: 19640317, by Toomey R, Alpern R, Vasterling JJ, Baker DG, Reda DJ, Lyons MJ, Henderson WG, Kang HK, Eisen SA, Murphy FM. Research Service, Boston VA Healthcare System, Boston, Massachusetts, USA. [E-mail:]

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Article Comments Post a Comment

VA ends Gulf War illness research contract
Posted by: Jagmedic
Aug 27, 2009
=========== The bottom line is that the V.A. does not want to find out what has happened to these veterans. It gives them "plausible deniability". Dr. Haley is a respected researcher and excellent physician. By pulling the rug out from under him, the V.A. effectively put the brakes on any resolution to this vexing problem. ================ Gulf War vets who suffer from chronic undiagnosed sympthoms, had seeked research which was not weighed by polictics of the day. War is a Racket and we hope big Pham get in the way of seeking treatments for our ilness. That can not happen now. Currently VA research is not looking at neurological exposures. We will continue to die younger than Vietnam vets. Most vets death cerificates fail to document Gulf war Exposure at all. 75% of all Vets who apply for undiagnosed illness Rating are DENIED. VA - Advisory Committee on Gulf War Veterans Department of Veterans Affairs Office of Policy and Planning (008A1) 810 Vermont Ave, Washington, DC 20420 202-461-5758 Lelia P. Jackson, Policy Analyst ,
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