Activate Now
 
ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

High dose vitamin D3 supplementation lowers inflammatory T cells in multiple sclerosis patients

Chocolate's Potential Health Benefits – and its Effect on Chronic Fatigue Syndrome Patients

Repair Damaged Mitochondria and Reduce Fatigue Up to 45%

Essential Oils - How and Where to Use Them

The Link Between Vitamin C And Optimal Immunity

SURVEY: What Is Your Diagnosis?

Liposomes Deliver Optimal Nutrient Absorption

Why Does Your Nose Run When It's Cold Outside?

What's So Great About Grape Seed?

How Your Mitochondria Influence Your Health

 
Print Page
Email Article

Worse and More Persistent Post-Surgical Pain Appears to Have Genetic Link

  [ 27 votes ]   [ Discuss This Article ]
www.ProHealth.com • November 1, 2009


A study presented at the 2009 Annual Meeting of the American Society of Anesthesiologists highlights the crucial importance of investigating multiple factors when designing studies that attempt to predict the development of persistent pain in patients.

Researchers specializing in anesthesiology and genetics at Oakland University (CA) William Beaumont School of Medicine were surprised to find that:

• Patients who carried a gene known for low sensitivity to pain

• Actually showed higher levels of pain at three months after surgery than other patients.

The study followed 58 patients who had undergone arthroscopic shoulder surgery for rotator cuff repair, a minimally invasive procedure that typically causes little postoperative pain. The patients also received nerve block anesthetics for home use to further reduce any lingering pain.

“Despite aggressive acute pain management, some patients still experienced significant pain and interference with activities that persisted for months, well beyond the usual period of healing,” said Dr. Craig T Hartrick, MD, who is Director of Anesthesiology Research at Oakland U.

The patients who still experienced pain at three months were paired with those who recovered from surgery uneventfully. Those who carried genes that better controlled the release of an enzyme known as COMT (catechol-O-methyl transferase) were examined to see if they resisted postsurgical pain better than the other patients. It has been suggested that patients with the very active form of COMT are protected from the development of temporomandibular joint dysfunction (TMJ), and possibly other forms of pain.

In the current study, patients with high anxiety before surgery had increased pain at three months, lower quality of life and increased feelings of sensitivity to pain. Again, when matched against other patients with similar anxiety levels, the low pain sensitivity COMT patients were actually experiencing the highest pain levels at three months.

“This may be explained due to the tendency for a reduced level of reported anxiety in the low pain sensitivity COMT subgroup of patients,” said Dr. Wendell, Associate Professor of Biological Sciences and Genetics at Oakland University.

Both Dr. Hartrick and Dr. Wendell stressed that developing pain strategies requires studying a vast array of factors, some of which are at least partially influenced by a person’s genetic makeup.

“While this study did not confirm an association between anxiety and COMT type, such an association could explain the apparent paradox in our findings and thus may represent an important confounder affecting pain assessments and pain studies that examine the genetic role of COMT.”

Source: American Society of Anesthesiologists (www.asahq.org) press release, Oct 20, 2009, modified




Post a Comment

Featured Products From the ProHealth Store
Vitamin D3 Extreme™ Mitochondria Ignite™ with NT Factor® Energy NADH™ 12.5mg

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products


Article Comments



Be the first to comment on this article!

Post a Comment


 
Free Chronic Fatigue Syndrome and Fibromyalgia Newsletters
Subscribe to
Our FREE
Newsletter
Subscribe Now!
Receive up-to-date ME/CFS, Fibromyalgia & Lyme Disease treatment and research news
 Privacy Guaranteed  |  View Archives

How Glutathione Can Save Your Life

Featured Products

Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium

Natural Remedies

Carry a Massage Therapist in Your Pocket Carry a Massage Therapist in Your Pocket
Coconut Oil - Healthy Gifts from the 'Tree of Life' Coconut Oil - Healthy Gifts from the 'Tree of Life'
Sleep Like a Baby in Nature's Cradle Sleep Like a Baby in Nature's Cradle
Secret Nutrient for Radiant Skin Secret Nutrient for Radiant Skin
Irritable Bowel Syndrome: Unlocking the Secrets of Peppermint, Acacia and Fennel Irritable Bowel Syndrome: Unlocking the Secrets of Peppermint, Acacia and Fennel

FIBROMYALGIA
What is Fibromyalgia?
Fibromyalgia Diagnosis
Fibromyalgia Symptoms
Fibromyalgia Causes
Fibromyalgia Treatments
Fibromyalgia Diet
Fibromyalgia Medications
M.E. & CFS
What is M.E./CFS?
M.E./CFS Diagnosis
M.E./CFS Symptoms
M.E./CFS Causes
M.E./CFS Treatments
M.E./CFS Diet
M.E./CFS Medications
LYME DISEASE
What is Lyme Disease?
Lyme Disease Diagnosis
Lyme Disease Symptoms
Lyme Disease Causes
Lyme Disease Treatments
Lyme Disease Diet
Lyme Disease Medications
FORUMS
Fibromyalgia
M.E. & CFS
Lyme Disease
General Health
WHOLESALE
AFFILIATES GUARANTEE
PRIVACY
CONTACT US
LIBRARY
RSS
SITE MAP
ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus
Credit Card Processing