Activate Now
 
ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help

Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

How One LLND Treats Lyme disease and Co-infections Using Natural Medicine

12 Celebrities with Lyme Disease

Sexual Transmission of Lyme Disease: a Paradigm Shift

Single Low-magnitude Electric Pulse Successfully Fights Inflammation

How Essential Oils Can Help Improve Your Life

Omega-3 fatty acids may help improve treatment, quality of life in cancer patients

Why Is Spicy Food Good for You?

Parasites and Worms As Major Complicating Co-Factors In Lyme Disease Recovery

Ask the Doctor- Is it possible to be fully healed from or cured of Lyme Disease?

Anti-histamine drug Claritin can kill Borrelia by interfering with manganese utilization

 
Print Page
Email Article

Omega-3 Levels Linked to Speed of Biological Aging

  [ 30 votes ]   [ 2 Comments ]
www.ProHealth.com • January 19, 2010


Omega-3 fatty acids may protect against cellular aging, according to a 5-year tracking study published Jan 19 in JAMA.(1)

The study of patients with cardiovascular disease found that higher omega-3 fatty acid blood levels were associated with less shortening of the telomeres – ‘caps’ on the ends of chromosomes that protect them from deterioration and are emerging as a marker of biological age.

Several studies have also shown increased survival rates among individuals with established cardiovascular disease who consume generous amounts of marine omega-3 fatty acids (fish & krill oil).

It is known that telomeres are involved in the replication and stability of the chromosome, and that genetic factors and environmental stressors can shorten them. But the mechanisms underlying the omega-3 oils’ protective effect are not well understood, according to background information in the article.

Ramin Farzaneh-Far, MD, of the University of California, San Francisco, and colleagues conducted a study to determine whether omega-3 fatty acid blood levels were associated with changes in leukocyte (a type of blood cell) telomere length in a study of 608 outpatients with stable coronary artery disease. The patients were recruited between September 2000 and December 2002 for the Heart and Soul Study, and followed up to January 2009 (median [midpoint], 6.0 years).

The researchers measured leukocyte telomere length at the beginning of the study and again after 5 years of follow-up. Multivariable models were used to examine the association of baseline levels of omega-3 fatty acids (docosahexaenoic acid [DHA] and eicosapentaenoic acid [EPA]) with subsequent change in telomere length.

The researchers found that individuals in the lowest quartile of DHA+EPA experienced the most rapid rate of telomere shortening, whereas those in the highest quartile experienced the slowest rate of telomere shortening.

“Levels of DHA+EPA were associated with less telomere shortening before and after sequential adjustment for established risk factors and potential confounders,” the researchers write. "Each 1-standard deviation increase in DHA+EPA levels was associated with a 32 percent reduction in the odds of telomere shortening.

"In summary, among patients with stable coronary artery disease, there was an inverse relationship between baseline blood levels of marine omega-3 fatty acids and the rate of telomere shortening over 5 years. These findings raise the possibility that omega-3 fatty acids may protect against cellular aging in patients with coronary heart disease.”
___
1. Article cited: “Association of marine omega-3 fatty acid levels with telomeric aging in patients with coronary heart disease,”   Rarzaney-Far R, et al., JAMA, Jan 20, 2010.

Source: American Medical Association news release, Jan 19, 2009



Please Discuss This Article:   Post a Comment 

JAMA 2010; 303: 250-257: Omega-3 Fatty Acids and Telomeres in Coronary Heart Disease
Posted by: James Michael Howard
Jan 20, 2010
JAMA. 2010;303(3):250-257: Association of Marine Omega-3 Fatty Acid Levels With Telomeric Aging in Patients With Coronary Heart Disease It is my hypothesis that DHEA was selected by evolution because it optimizes replication and transcription of DNA. Therefore, all tissues will be affected by the reduction in DHEA which naturally begins around age twenty, reaching very low levels in old age. Low DHEA will be involved in coronary artery disease. It has been determined that docosahexaenoic acid positively affects levels of DHEA in a "concentration-dependent" manner (J Vet Med Sci. 2007 Jan;69(1):49-54). I wrote a paper explaining the connection of DHEA and telomere length in 2004: http://anthropogeny.com/Telomeres.htm . I suggest these findings may be explained by increases in DHEA and that the benefits of fish oil, that is, docosahexaenoic acid, are due to increases in DHEA. James Michael Howard, Fayetteville, Arkansas, U.S.A.
Reply Reply

JAMA 2010; 303: 250-257: Omega-3 Fatty Acids and Telomeres in Coronary Heart Disease
Posted by: James Michael Howard
Jan 20, 2010
JAMA. 2010;303(3):250-257: Association of Marine Omega-3 Fatty Acid Levels With Telomeric Aging in Patients With Coronary Heart Disease It is my hypothesis that DHEA was selected by evolution because it optimizes replication and transcription of DNA. Therefore, all tissues will be affected by the reduction in DHEA which naturally begins around age twenty, reaching very low levels in old age. Low DHEA will be involved in coronary artery disease. It has been determined that docosahexaenoic acid positively affects levels of DHEA in a "concentration-dependent" manner (J Vet Med Sci. 2007 Jan;69(1):49-54). I wrote a paper explaining the connection of DHEA and telomere length in 2004: http://anthropogeny.com/Telomeres.htm . I suggest these findings may be explained by increases in DHEA and that the benefits of fish oil, that is, docosahexaenoic acid, are due to increases in DHEA. James Michael Howard, Fayetteville, Arkansas, U.S.A.
Reply Reply
 
Free Chronic Fatigue Syndrome and Fibromyalgia Newsletters
Subscribe to
Our FREE
Newsletter
Subscribe Now!
Receive up-to-date ME/CFS & Fibromyalgia treatment and research news
 Privacy Guaranteed  |  View Archives

Save on Nutritional Supplement Orders

Featured Products

Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid

Natural Remedies

Research Links Green Tea to Weight Loss Research Links Green Tea to Weight Loss
The Fast-Acting Solution for Healthy Digestive Function The Fast-Acting Solution for Healthy Digestive Function
Magnesium: An Essential Supplement for ME/CFS Magnesium: An Essential Supplement for ME/CFS
Optimize Your Immune System Naturally: Thymic Protein A Optimize Your Immune System Naturally: Thymic Protein A
Health Benefits Are Brewing in Green Tea Health Benefits Are Brewing in Green Tea

FIBROMYALGIA RESOURCES
What is Fibromyalgia?
Fibromyalgia Diagnosis
Fibromyalgia Symptoms
Fibromyalgia Treatments
| CFS RESOURCES
What is CFS?
ME/CFS Diagnosis
ME/CFS Symptoms
ME/CFS Treatments
| FORUMS
Fibromyalgia
ME/CFS
ADVANCED MEDICAL LABS
WHOLESALE  |  AFFILIATES
GUARANTEE  |  PRIVACY
CONTACT US
LIBRARY
RSS
SITE MAP
ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus
Credit Card Processing