Activate Now
 
ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Acupuncture used in clinical settings reduced symptoms of menopause

Benefits of Coconut Oil Are Undeniable

How Awesome Is Ashwagandha?

CoQ10 supplementation associated with lower pro-inflammatory factors in randomized trial

SURVEY RESULTS: Should Opioids Be Restricted for Chronic Illness?

Clinical trial demonstrates success of low FODMAP diet

Research Demonstrates Superiority of Krill Oil Compared to Fish Oil

Vitamin nicotinamide riboside protects mice from diabetes complications

What’s so Remarkable About Rosemary?

Vitamin-mineral supplement prevents brain cell loss in recent research

 
Print Page
Email Article

Host range and cellular tropism of the human exogenous gammaretrovirus XMRV – Source: Virology, Jan 26, 2010

  [ 6 votes ]   [ Discuss This Article ]
By Kristin Stieler, Nicole Fischer, et al. • www.ProHealth.com • February 1, 2010


Recently, the first human infection with an exogenous gammaretrovirus (XMRV) was reported.

In its initial description, XMRV was confined to prostate stromal fibroblasts [cells in connective tissue], although subsequent reports demonstrated XMRV protein expression in prostate epithelial cells [in the organ’s lining].

Most recently, XMRV has been detected in blood cells of patients with chronic fatigue syndrome.

The aim of this study was to elucidate the transmission routes and tissue tropism [tissue that supports the growth] of XMRV by comparing its host range, receptor usage and LTR functionality with other MLV isolates. [the LTR or “long terminal repeat” of a retrovirus “is the control center for gene expression.” MLV is amphotropic murine leukemia virus.]

• We demonstrate using pseudotype experiments that XMRV Env mediates efficient infection of cells from different species.

• We show that replication competent XMRV infects various human cell types, including hematopoietic cell lines and prostate stromal fibroblasts. [Hematopoietic stem calls, found in the bone marrow, give rise to all the blood cell types.]

• XMRV-LTR activity is significantly higher in the prostate cancer cell line LNCaP and in prostate stromal fibroblasts, compared to other cell types tested and could be one factor contributing to efficient viral spread in prostate tissue.

Source: Virology, Jan 26, 2010. PMID: 20110097, by Stieler K, Schulz C, Lavanya M, Aepfelbacher M, Stocking C, Fischer N. Institute for Medical Microbiology and Virology, University Medical Center Eppendorf, Hamburg, Germany; Heinrich-Pette-Institute, Hamburg, Germany; Institut de Genetique Moleculaire de Montpellier, Montpellier, France. [E-mail: nfischer@uke.de]





Post a Comment

Featured Products From the ProHealth Store
Optimized Curcumin Longvida® FibroSleep™ Ultra EPA  - Fish Oil

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products


Article Comments



Be the first to comment on this article!

Post a Comment


 
All Natural Deodorants

Featured Products

FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength
Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function

Natural Remedies

Live Without Anxiety or Stress
Reversing Neurodegeneration with a New Magnesium Compound Reversing Neurodegeneration with a New Magnesium Compound
Optimize Your Immune System Naturally: Thymic Protein A Optimize Your Immune System Naturally: Thymic Protein A
The Brain Boosting and Fatigue Fighting B-12 The Brain Boosting and Fatigue Fighting B-12
More Weight Loss than Any Other Discovery in Supplement History More Weight Loss than Any Other Discovery in Supplement History

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler

· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE AND SAVE 15% NOW*
Be the first to know about new products, special discounts and the latest health news. *New subscribers only

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2016 ProHealth, Inc. All rights reserved. Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map