ProHealth health Vitamin and Natural Supplement Store and Health
Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help

|
|
|
|
 
Print Page
Email Article

Efficacy of oral cobalamin (vitamin B12) therapy – Source: Expert Opinion on Pharmacotherapy, Feb 2010

  [ 32 votes ]   [ Post a Comment ]
By Emmanuel Andres, et al. • www.ProHealth.com • February 5, 2010

previous article next article

Importance of the field: Cobalamin (vitamin B12) deficiency is particularly common in the elderly (more than 15%). Management of cobalamin deficiency with cobalamin injections is well codified at present, but new routes of cobalamin administration (oral and nasal) are being studied, especially oral cobalamin therapy for food-cobalamin malabsorption.

Areas covered in this review:

The objective of this review is to evaluate the efficacy of oral cobalamin treatment in elderly patients.

To reach this objective, PubMed data were systematically searched for English and French articles published from January 1990 to July 2008.

Data from our research group on cobalamin deficiency (Groupe d’Etude des CAREnce vitamine B12 – CARE B12) were also analyzed.

What the reader will gain:

Three prospective randomized studies, a systematic review by the Cochrane group and five prospective cohort studies were found and provide evidence that oral cobalamin treatment may adequately treat cobalamin deficiency.

The efficacy was particularly highlighted when looking at the marked improvement in serum vitamin B12 levels and hematological parameters, for example hemoglobin level, mean erythrocyte cell volume and reticulocyte count.

The effect of oral cobalamin treatment in patients presenting with severe neurological manifestations has not yet been adequately documented. Oral cobalamin treatment avoids the discomfort, inconvenience and cost of monthly injections.

Take home message: Our experience and the present analysis support the use of oral cobalamin therapy in clinical practice.

Source:
Expert Opinion on Pharmacotherapy, Feb 2010; 11(2), 249-256. PMID: PMID: 20088746, by Andres E, Fothergill H, Mecili M. Hopital Civil – Hopitaux Universitaires de Strasbourg; Department of Internal Medicine, Diabetes and Metabolic Diseases, Clinique Medicale B, Strasbourg; Hopitaux Universitaires de Strasbourg, Department of Pediatrics, Strasbourg, France. [E-mail: emmanuel.andres@chru-strasbourg.fr]



previous article
  Rating 3.4 (32 votes) next article




DISCUSS THIS ARTICLE   (0 existing comments) Post a Comment 




[ Be the first to comment on this article ]




 
Free Chronic Fatigue Syndrome and Fibromyalgia Newsletters
Subscribe to
Our FREE
Newsletter
Subscribe Now!
Receive up-to-date ME/CFS & Fibromyalgia treatment and research news
 Privacy Guaranteed  |  View Archives

Save on Your Next Order

Featured Products
Vitamin D3 5000 IU Vitamin D3 5000 IU
Give your body a boost with the sunshine vitamin
OsteoTec™ UC-II® OsteoTec™ UC-II®
A True Breakthrough in Joint health
Natural Resveratrol Natural Resveratrol
Powerful Antioxidant Support + Positive Anti-aging Effects
Omega 3-6-9 Omega 3-6-9
All three EFAs in one convenient form
Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength

Most Viewed Articles
What's the Hidden Cause Behind YOUR Fibromyalgia Flares? [more]

Pridgen Reports Fibromyalgia Antiviral Trial Results “Very Positive”: Predicts New Approach Will Be ... [more]

How to Limit or Minimize Your Fibromyalgia Flare [more]

VIDEO: IACFS/ME Conference - Summary of Research by Dr. Komaroff [more]

Mitochondrial Dysfunction, Post-Exertional Malaise and CFS/ME [more]

The Devil Is In The Details – A Herpes Simplex Virus Inquiry For Fibromyalgia and Chronic Fatigue Sy... [more]

Sympathetic Nervous System Dysfunction in FIbromyalgia and Overlapping Conditions [more]

Review of Nutritional Supplements Used for ME/CFS and FM [more]

FREE: Stop Feeding Yourself PAIN Guide [more]

Sympathetic nervous system dysfunction in fibromyalgia, chronic fatigue syndrome, irritable bowel sy... [more]


FIBROMYALGIA RESOURCES
What is Fibromyalgia?
Fibromyalgia 101
Fibromyalgia Symptoms
Fibromyalgia Treatments
| CFS RESOURCES
What is CFS?
ME/CFS 101
ME/CFS Symptoms
ME/CFS Treatments
| FORUMS
Fibromyalgia
ME/CFS
ADVANCED MEDICAL LABS
WHOLESALE  |  AFFILIATES
GUARANTEE
CONTACT US
PRIVACY
RSS
SITE MAP
ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus
Credit Card Processing