Objective: To examine the 5-year outcome in a cohort of children with "growing pains" and the association with changes in pain threshold.
Study Design: Subjects were 44 children with growing pains studied previously, and controls were 38 pain-free children matched by sex and age. Current status of growing pains and other pain syndromes were assessed by parental questionnaires. Pain threshold was measured with a Fisher-type dolorimeter. Outcomes were correlated with the pain threshold.
Results: We examined 35/44 patients (80%) after 5 years.
• Eighteen patients (51%) experienced resolution of growing pains.
• In 14 of the 17 patients with persistent growing pains (83%), episodes were less frequent and milder.
• The prevalence of accompanying pain syndromes decreased from 20% to 14%. No patient developed fibromyalgia.
• Pain thresholds were similar in the entire growing pains cohort and healthy controls,
• But those with continued growing pains had significantly lower thresholds than controls (P <.05) and patients with resolved growing pains (P <.02).
Conclusions: We confirm that growing pains has a benign prognosis and probably represents a pain amplification syndrome of early childhood.
Source: The Journal of Pediatrics, Feb 22, 2010. PMID: 20171654, by Uziel Y, Chapnick G, Jaber L, Nemet D, Hashkes PJ. Tel-Aviv University, Sackler School of Medicine, Department of Pediatrics, Meir Medical Center, Kfar Saba, Israel; Department of Rheumatic Diseaes, Cleveland Clinic, Ohio, USA. [E-mail: firstname.lastname@example.org]