ProHealth health Vitamin and Natural Supplement Store and Health
Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help

|
|
|
|

Trending News

New Science Destroys the Saturated Fat Myth

Diet Affects Men’s and Women’s Gut Microbes Differently

New Lyme guidelines promote options and informed choice

Phases of clinical depression could affect treatment

“Worm pill” could ease autoimmune disease symptoms

Eating Baked or Broiled Fish Weekly Boosts Brain Health, Pitt Study Says

Scientists Look for Biomarkers to Improve Treatment of Painful Bladder Condition

New culprit identified in metabolic syndrome

Low vitamin D levels linked to increased risks after noncardiac surgery

Preserving Cognitive Function with Aging

 
Print Page
Email Article

EPA [fish oil] supplementation improves teacher rated behavior and oppositional symptoms in children with ADHD – Source: Acta Paediatrica, May 19, 2010

  [ 23 votes ]   [ Discuss This Article ]
By Per A Gustafsson, MD, PhD, et al • www.ProHealth.com • June 1, 2010


Aim: Measure efficacy of EPA in children with ADHD. [Note: EPA is eicosapentaenoic acid – an omega-3 essential fatty acid derived from oily fish or fish oil (or for nursing infants, breast milk). Physiologically it is required in high levels in the brain and is essential for optimal neuronal functioning.]

Methods: Randomized controlled trial of 0.5g EPA or placebo (15 weeks) in 92 children (7-12 years) with ADHD. Efficacy measure was Conners' Parent/Teacher Rating Scales (CPRS/CTRS).

Fatty acids were analyzed in serum phospholipids and red blood cell membranes (RBC) at baseline and endpoint with gas chromatography.

Results:

• EPA improved CTRS inattention/cognitive subscale (p = 0.04), but not Conners' total score.

• In oppositional children (n = 48) CTRS total score improved 25% or more in 48% of the children receiving EPA vs. 9% for placebo (ES 0.63, p = 0.01). [Note: oppositional children may express defiance and anger along with attention/hyperactivity problems.]

• In less hyperactive/impulsive children (n = 44), 25% or greater improvement was seen in 36% vs. 18% (ES 0.41, n.s.),

• And with both these types of symptoms 8 of 13 with EPA vs. 1 of 9 for placebo improved 25% or more (p = 0.03).

• Children responding to treatment had lower EPA concentrations (p = 0.02), higher AA/EPA (p = 0.005) and higher AA/DHA ratios (p = 0.03) in serum at baseline.

• Similarly, AA/EPA (p = 0.01), AA/DHA (p = 0.038) and total omega-6/omega-3 ratios (p = 0.028) were higher in RBC, probably due to higher AA (p = 0.011).

Conclusion:

• Two ADHD subgroups (oppositional and less hyperactive/impulsive children) improved after 15 weeks EPA treatment.

• Increasing EPA and decreasing omega-6 fatty acid concentrations in phospholipids were related to clinical improvement. [Note: plant oil-derived omega-6 fatty acids are also essential, but the average Western diet includes more than 10 times the proper amount via commercial/processed foods.]

Source: Acta Paediatrica, May 19, 2010. PMID: 20491709, by Gustafsson PA, Birberg-Thornberg U, Duchén K, Landgren M, Malmberg K, Pelling H, Strandvik B, Karlsson T. Departments of Child Psychiatry, Behavioral Sciens and Learning, and Pediatrics, Linköping University; Dept of Pediatrics, Mariestad, Dept of Child Psychiatry  Karolinska Institute,  Uppsala University ;  Dept of Pediatrics, Gothenburg University; Dept of Biosciences and Nutrition, NOVUM, Karolinska Institute, Stockholm, Sweden.  [Email: Per.A.Gustafsson@liu.se]




Please Discuss This Article:   Post a Comment 



[ Be the first to comment on this article ]




 
Free Chronic Fatigue Syndrome and Fibromyalgia Newsletters
Subscribe to
Our FREE
Newsletter
Subscribe Now!
Receive up-to-date ME/CFS & Fibromyalgia treatment and research news
 Privacy Guaranteed  |  View Archives

Save on Your Next Order

Featured Products

Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
Optimized Curcumin Longvida® by ProHealth Optimized Curcumin Longvida® by ProHealth
Supports Cognition, Memory & Overall Health

Natural Remedies

Are You Obtaining the Proper Enzymes? Are You Obtaining the Proper Enzymes?
Anti-Inflammatory Properties of Tart Cherry Anti-Inflammatory Properties of Tart Cherry
Why Berries Offer a Rainbow of Health Benefits Why Berries Offer a Rainbow of Health Benefits
Research Links Green Tea to Weight Loss Research Links Green Tea to Weight Loss
Broad Spectrum Protection Against Brain Aging Broad Spectrum Protection Against Brain Aging

FIBROMYALGIA RESOURCES
What is Fibromyalgia?
Fibromyalgia 101
Fibromyalgia Symptoms
Fibromyalgia Treatments
| CFS RESOURCES
What is CFS?
ME/CFS 101
ME/CFS Symptoms
ME/CFS Treatments
| FORUMS
Fibromyalgia
ME/CFS
ADVANCED MEDICAL LABS
WHOLESALE  |  AFFILIATES
GUARANTEE
CONTACT US
PRIVACY
RSS
SITE MAP
ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus
Credit Card Processing