Activate Now
ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Repair Damaged Mitochondria and Reduce Fatigue Up to 45%

How One LLND Treats Lyme disease and Co-infections Using Natural Medicine

SURVEY RESULTS: Has Your Illness Affected What You Eat?

New depression diagnosis and treatment

Surprising Benefits of Cinnamon

Specific vitamin D levels linked to heart problems

A Sleep Intervention For Children With Autism: A Pilot Study

Higher vitamin D levels may be protective against acute rhinosinusitis

Real Life as a Mom with Chronic Illness

Saffron reduces oxidative stress in metabolic syndrome patients

Print Page
Email Article

Autism ‘Metabolic Fingerprint’ Discovered - Diagnosis by Simple Urine Test Foreseen

  [ 36 votes ]   [ Discuss This Article ] • June 4, 2010

People with autism suffer from gastrointestinal disorders and have a different makeup of bacteria in their gut. Cause or consequence?

Children with autism have a different chemical fingerprint in their urine than non-autistic children, according to new research published June 4 by the Journal of Proteome Research.(1)

The researchers behind the study, from Imperial College London and the University of South Australia, suggest that their findings could ultimately lead to a simple urine test to determine whether or not a young child has autism.

• Autism affects an estimated 1 in every 100 people in the UK.

• People with autism have a range of different symptoms, but they commonly experience problems with communication and social skills, such as understanding other people's emotions and making conversation and eye contact.

• People with autism are also known to suffer from gastrointestinal disorders, and they have a different makeup of bacteria in their guts from non-autistic people.

This research shows that it is possible to distinguish between autistic and non-autistic children by looking at the by-products of gut bacteria and the body's metabolic processes in the children's urine.

The exact biological significance of gastrointestinal disorders in the development of autism is unknown.

The distinctive urinary metabolic fingerprint for autism identified in this study could form the basis of a non-invasive test that might help diagnose autism earlier.

This would enable autistic children to receive assistance, such as advanced behavioral therapy, earlier in their development than is currently possible.

At present, children are assessed for autism through a lengthy process involving a range of tests that explore the child's social interaction, communication and imaginative skills.

Early intervention can greatly improve the progress of children with autism but it is currently difficult to establish a firm diagnosis when children are under 18 months of age, although it is likely that changes may occur much earlier than this.

The researchers suggest that their new understanding of the makeup of bacteria in autistic children's guts could also help scientists to develop treatments to tackle autistic people's gastrointestinal problems.

Professor Jeremy Nicholson, the corresponding author of the study and head of Surgery and Cancer at Imperial College London, said:

• "Autism is a condition that affects a person's social skills, so at first it might seem strange that there's a relationship between autism and what's happening in someone's gut.

• “However, your metabolism and the makeup of your gut bacteria reflect all sorts of things, including your lifestyle and your genes.

• “Autism affects many different parts of a person's system, and our study shows that you can see how it disrupts their system by looking at their metabolism and their gut bacteria.

"We hope our findings might be the first step towards creating a simple urine test to diagnose autism at a really young age, although this is a long way off - such a test could take many years to develop and we're just beginning to explore the possibilities. We know that giving therapy to children with autism when they are very young can make a huge difference to their progress. A urine test might enable professionals to quickly identify children with autism and help them early on," he added.

The researchers are now keen to investigate whether metabolic differences in people with autism are related to the causes of the condition or are a consequence of its progression.

The researchers reached their conclusions by using H NMR Spectroscopy to analyze the urine of three groups of children aged between 3 and 9:

• 39 children who had previously been diagnosed with autism,

• 28 non-autistic siblings of children with autism, and

• 34 children who did not have autism and who did not have an autistic sibling.

They found that each of the three groups had a distinct chemical fingerprint.

• Non-autistic children with autistic siblings had a different chemical fingerprint than those without any autistic siblings,

• And autistic children had a different chemical fingerprint than the other two groups.

1. Article - “Urinary Metabolic phenotyping differentiates children with autism from their unaffected siblings and age-matched controls,” Ivan KS, Nicholson JK, et al.

Source: Journal of Proteome Research & Imperial College London, news release, Jun 3, 2010

Post a Comment

Featured Products From the ProHealth Store
Ultra EPA  - Fish Oil Optimized Curcumin Longvida® Vitamin D3 Extreme™

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products

Article Comments

Be the first to comment on this article!

Post a Comment

Free Chronic Fatigue Syndrome and Fibromyalgia Newsletters
Subscribe to
Subscribe Now!
Receive up-to-date ME/CFS, Fibromyalgia & Lyme Disease treatment and research news
 Privacy Guaranteed  |  View Archives

Repair Damaged Mitochondria and Reduce Fatigue Up to 45%

Featured Products

Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function

Natural Remedies

Block food Cravings At Their Molecular Root Block food Cravings At Their Molecular Root
Can Glycine + Amino Acids Be the Secret to Deep, Rejuvenating Sleep? Can Glycine + Amino Acids Be the Secret to Deep, Rejuvenating Sleep?
Curcumin - a Golden Gift of Nature with Benefits Still Untold Curcumin - a Golden Gift of Nature with Benefits Still Untold
Secret Nutrient for Radiant Skin Secret Nutrient for Radiant Skin
Itching to Find Dry Skin Relief? Itching to Find Dry Skin Relief?

What is Fibromyalgia?
Fibromyalgia Diagnosis
Fibromyalgia Symptoms
Fibromyalgia Causes
Fibromyalgia Treatments
Fibromyalgia Diet
Fibromyalgia Medications
M.E. & CFS
What is M.E./CFS?
M.E./CFS Diagnosis
M.E./CFS Symptoms
M.E./CFS Causes
M.E./CFS Treatments
M.E./CFS Diet
M.E./CFS Medications
What is Lyme Disease?
Lyme Disease Diagnosis
Lyme Disease Symptoms
Lyme Disease Causes
Lyme Disease Treatments
Lyme Disease Diet
Lyme Disease Medications
M.E. & CFS
Lyme Disease
General Health
ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus
Credit Card Processing