Activate Now
 
ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

The New Dual Activation Pain Relief Cream

The Importance of B Vitamins for Brain Health and Combating Dementia

SURVEY RESULTS: Medical Marijuana

High serum omega-6 polyunsaturated fatty acid concentrations linked to lower risk of type 2 diabetes

Recipe: Mega-Golden Milk

Vitamin D supplementation shows promise for Hashimoto's thyroiditis

A Paleolithic-type diet may help reduce future risk of diabetes and cardiovascular disease

Large whey protein breakfast may help manage type 2 diabetes

Meta-analysis adds evidence to antidepressant effect for omega-3

Higher vitamin C intake may help slow cataract progression

 
Print Page
Email Article

Nutritional and herbal supplements for anxiety and anxiety-related disorders: Systematic review – Source: Nutrition Journal, Oct 7, 2010

  [ 15 votes ]   [ Discuss This Article ]
By Shaheen E Lakhan, Karen F Vieira • www.ProHealth.com • October 22, 2010


[Note: to read the full text & tables of this review of clinical trials testing herbal / nutritional supplements as support for relief of anxiety disorders, click here.]

Background: Over the past several decades, complementary and alternative medications have increasingly become a part of everyday treatment. With the rising cost of prescription medications and their production of unwanted side effects, patients are exploring herbal and other natural remedies for the management and treatment of psychological conditions.

Psychological disorders are one of the most frequent conditions seen by clinicians, and often require a long-term regimen of prescription medications. Approximately 6.8 million Americans suffer from generalized anxiety disorder.

Many also suffer from the spectrum of behavioral and physical side effects that often accompany its treatment. It is not surprising that there is universal interest in finding effective natural anxiolytic (anti-anxiety) treatments with a lower risk of adverse effects or withdrawal.

Methods: An electronic and manual search was performed through MEDLINE/PubMed and EBSCO. Articles were not discriminated by date of publication. Available clinical studies published in English that used human participants and examined the anxiolytic potential of dietary and herbal supplements were included. Data were extracted and compiled into tables that included the study design, sample population, intervention, control, length of treatment, outcomes, direction of evidence, and reported adverse events.

Results: A total of 24 studies that investigated five different CAM monotherapies and eight different combination treatments and involved 2,619 participants met the inclusion criteria and were analyzed. There were 21 randomized controlled trials and three open-label, uncontrolled observational studies.

Most studies involved patients who had been diagnosed with either an anxiety disorder or depression (n = 1786). However, eight studies used healthy volunteers (n = 877) who had normal levels of anxiety, were undergoing surgery, tested at the upper limit of the normal range of a trait anxiety scale, had adverse premenstrual symptoms or were peri-menopausal, reported anxiety and insomnia, or had one month or more of elevated generalized anxiety.

Heterogeneity and the small number of studies for each supplement or combination therapy prevented a formal meta-analysis.

Of the randomized controlled trials reviewed, 71% (15 out of 21) showed a positive direction of evidence.

Any reported side effects were mild to moderate.

Conclusions: Based on the available evidence, it appears that nutritional and herbal supplementation is an effective method for treating anxiety and anxiety-related conditions without the risk of serious side effects.

There is the possibility that any positive effects seen could be due to a placebo effect, which may have a significant psychological impact on participants with mental disorders.

However, based on this systematic review:

• Strong evidence exists for the use of herbal supplements containing extracts of passionflower or kava and combinations of [amino acids] L-lysine and L-arginine as treatments for anxiety symptoms and disorders.

Magnesium-containing supplements, and other herbal combinations may hold promise, but more research is needed before these products can be recommended to patients.

• St. John's wort monotherapy has insufficient evidence for use as an effective anxiolytic treatment.

Source: Nutrition Journal, Oct 7, 2010;9:42. PMID: 20929532, by Lakhan SE, Vieira KF. Global Neuroscience Initiative Foundation, Los Angeles, California, USA. [Email: slakhan@gnif.org]





Post a Comment

Featured Products From the ProHealth Store
FibroSleep™ Magnesium Plus L-Theanine Calm-Plex with GABA & 5-HTP (Suntheanine®)

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products


Article Comments



Be the first to comment on this article!

Post a Comment


 
Aching for Pain Relief?

Featured Products

Magnesium Plus Magnesium Plus
Natural mineral for nerve & muscle function
L-Theanine Calm-Plex with GABA & 5-HTP (Suntheanine®) L-Theanine Calm-Plex with GABA & 5-HTP (Suntheanine®)
Synergistic Formula Enhances Mood & Well-being
Amino Acid Complex™ Amino Acid Complex™
Quickly-absorbed Building Blocks for a Stronger body
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid

Natural Remedies

Aches and Pains? A Simple Solution You'll Love Aches and Pains? A Simple Solution You'll Love
Safely Burn Away Body Fat Safely Burn Away Body Fat
SAM-e: a Hard-Working Molecule that May Help Ease Pain & Brighten Mood SAM-e: a Hard-Working Molecule that May Help Ease Pain & Brighten Mood
Stop Bacteria With Nature's Antibiotics Stop Bacteria With Nature's Antibiotics
Help for Soreness and Swelling: What Do Silkworms Have to Do With It? Help for Soreness and Swelling: What Do Silkworms Have to Do With It?

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler

· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE AND SAVE 15% NOW*
Be the first to know about new products, special discounts and the latest health news. *New subscribers only

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2016 ProHealth, Inc. All rights reserved. Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map