Activate Now
 
ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

SURVEY RESULTS: Medical Marijuana

Decreased levels of vitamin D associated with reduced methylation in African American teens

Sweep Away Senile Cells

PAIN'S SECRET MESSAGE: Why Prince Didn't Need to Die

8 Hacks to Slash Medication Costs

New Study Shows Optimized Curcumin Stops Inflammation

Relief from Common Digestive Distress

Block The Vascular Origins Of Cognitive Decline

Curcumin: Your Secret Weapon to Speed Muscle Recovery After Intense Exercise

7 Natural Ways to Prevent Diabetes

 
Print Page
Email Article

Biological Mechanisms of Chronic Fatigue – Source: Rheumatology, Feb 1, 2011

  [ 16 votes ]   [ 1 Comment ]
By Katrine B Norheim, et al. • www.ProHealth.com • February 9, 2011


[Note: to read the free full text of this article providing an overview of the current science regarding chronic fatigue, click HERE. Concludes that large studies of genetic involvement and oxidative stress in well defined high-fatigue diseases are needed to further unravel the biological mechanisms involved.]

Chronic fatigue is a common, poorly understood and disabling phenomenon in many diseases. We aim to provide an overview of fatigue in chronic autoimmune and inflammatory disease.

Fatigue measurement, prevalence and confounding factors such as depression, sleep disorders and pain are reviewed in the first half of the article.

In the second half of the article, we describe explanatory models of fatigue and fatigue signaling, with an emphasis on:

• Cytokines and sickness behavior [The brain’s response to chemicals signaling inflammation-causing situations such as infection; prompting energy-saving behaviors designed to enhance ability to survive the situation],

• Oxidative stress [When reactive oxygen species (free radicals) outrun ability to control them, and the imbalance leads to damage of cellular components, including the energy-producing mitochondria. Compared to rust in a tin can],

• Mitochondrial dysfunction,

• And the impact of certain genes on fatigue.
 
Source: Rheumatology, Feb 1, 2011;50(2). Norheim KB, Jonsson G, Omdal R. Department of Internal Medicine, Clinical Immunology Unit, Stavanger University Hospital, Stavanger, Norway. [Email: omro@sus.no]





Post a Comment

Featured Products From the ProHealth Store
Vitamin D3 Extreme™ FibroSleep™ Mitochondria Ignite™ with NT Factor®

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products


Article Comments Post a Comment

Full text of article is NOT free
Posted by: shadiah
Feb 17, 2011
Just noting that the link provided is not to a free version of the full article.
Reply Reply
 
20 Helpful Tips for Cleaning and Organizing When You're Chronically Ill

Featured Products

Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid

Natural Remedies

Everything You Always Wanted to Know About Sleep But Were Too Tired to Ask Everything You Always Wanted to Know About Sleep But Were Too Tired to Ask
Undenatured Type II Collagen - Chicken Soup for Your Joints Undenatured Type II Collagen - Chicken Soup for Your Joints
Astaxanthin - A Little-Known but Power-Packed Nutrient Astaxanthin - A Little-Known but Power-Packed Nutrient
Running on Empty? Fuel Up with NADH Running on Empty? Fuel Up with NADH
Red Yeast Rice - Natural Option for Supporting Healthy Cholesterol Red Yeast Rice - Natural Option for Supporting Healthy Cholesterol

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler

· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE AND SAVE 15% NOW*
Be the first to know about new products, special discounts and the latest health news. *New subscribers only

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2016 ProHealth, Inc. All rights reserved. Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map