ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Curcumin: The All In One Solution, Part 2

CoQ10 — A Nutritional Powerhouse for Mitochondrial Health

How to Prevent Hearing Loss and Improve Your Hearing With Nutrition

What Are the Benefits of Vitamin K2?

Vitamin D deficiency + high fat diet = metabolic syndrome

Use Burdock Oil to Promote Healthy Hair Growth

Why You Should Take Your Apple Cider Vinegar at Night

AMA journal associates iron deficiency with hearing loss

Lutein linked to preservation of crystallized intelligence

Zinc eaten at levels found in biofortified crops reduces 'wear and tear' on DNA

 
Print Page
Email Article

Biological Mechanisms of Chronic Fatigue – Source: Rheumatology, Feb 1, 2011

  [ 16 votes ]   [ 1 Comment ]
By Katrine B Norheim, et al. • www.ProHealth.com • February 9, 2011


[Note: to read the free full text of this article providing an overview of the current science regarding chronic fatigue, click HERE. Concludes that large studies of genetic involvement and oxidative stress in well defined high-fatigue diseases are needed to further unravel the biological mechanisms involved.]

Chronic fatigue is a common, poorly understood and disabling phenomenon in many diseases. We aim to provide an overview of fatigue in chronic autoimmune and inflammatory disease.

Fatigue measurement, prevalence and confounding factors such as depression, sleep disorders and pain are reviewed in the first half of the article.

In the second half of the article, we describe explanatory models of fatigue and fatigue signaling, with an emphasis on:

• Cytokines and sickness behavior [The brain’s response to chemicals signaling inflammation-causing situations such as infection; prompting energy-saving behaviors designed to enhance ability to survive the situation],

• Oxidative stress [When reactive oxygen species (free radicals) outrun ability to control them, and the imbalance leads to damage of cellular components, including the energy-producing mitochondria. Compared to rust in a tin can],

• Mitochondrial dysfunction,

• And the impact of certain genes on fatigue.
 
Source: Rheumatology, Feb 1, 2011;50(2). Norheim KB, Jonsson G, Omdal R. Department of Internal Medicine, Clinical Immunology Unit, Stavanger University Hospital, Stavanger, Norway. [Email: omro@sus.no]





Post a Comment

Featured Products From the ProHealth Store
FibroSleep™ Energy NADH™ 12.5mg Ultra ATP+, Double Strength

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products


Article Comments Post a Comment

Full text of article is NOT free
Posted by: shadiah
Feb 17, 2011
Just noting that the link provided is not to a free version of the full article.
Reply Reply
 
NAD+ Ignite with Niagen

Featured Products

Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%

Natural Remedies

Eating Fat is Good... Maybe... Could Be... Sometimes Eating Fat is Good... Maybe... Could Be... Sometimes
Stop Bacteria With Nature's Antibiotics Stop Bacteria With Nature's Antibiotics
Mitochondria-Booster NIAGEN® Shows Promise in First Human Clinical Trial Mitochondria-Booster NIAGEN® Shows Promise in First Human Clinical Trial
Coping When Colds or Flu Catch Up with You Coping When Colds or Flu Catch Up with You
Undenatured Type II Collagen - Chicken Soup for Your Joints Undenatured Type II Collagen - Chicken Soup for Your Joints

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map