ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help

|
|
|
|

Trending News

Magnesium: An Invisible Deficiency That Could Be Harming Your Health

Fatigue & Fibro Fog: Could You Have a B-12 Deficiency?

“Next Generation” Vitamin Provides Hope To Aging Societies Worldwide

Advances in Understanding of Depression Offers New Hope

Resolved to lose weight in 2015? Here are five bad strategies to avoid

Safely Burn Away Body Fat

Vitamin K1 and K2—Two Underappreciated Nutrients That Are Crucial for Health

Year of birth significantly changes impact of obesity-associated gene variant

Curcumin's ability to fight Alzheimer's studied

Causal Link between Vitamin D, Serotonin Synthesis and Autism

 
Print Page
Email Article

POTS symptoms generally more severe in CFS patients, Vanderbilt finds

  [ 12 votes ]   [ Discuss This Article ]
www.ProHealth.com • September 14, 2011


Article:
Neurohumoral and Hemodynamic Profile in Postural Tachycardia and Chronic Fatigue Syndromes
– Source: Clinical Science, Sep 12, 2011

By Luis E Okamoto, Italo Biaggioni, et al.

Several studies recognized an overlap between chronic fatigue (CFS) and postural tachycardia (POTS) syndromes.

We compared the autonomic and neurohormonal phenotype of POTS patients with CFS (CFS-POTS) to those without CFS (non-CFS POTS), to determine whether CFS-POTS represents a unique clinical entity with a distinct pathophysiology.

We recruited 58 patients with POTS, of which 47 were eligible to participate: 93% of them reported severe fatigue (Checklist Individual Strength [CIS], fatigue subscale <36), and 64% (n=30) fulfilled criteria for CFS (CFS-POTS).

• The prevalence of CFS symptoms (Centers for Disease Control and Prevention criteria) was greater in the CFS-POTS group

• But the pattern of symptoms was similar in both groups.

• Physical functioning was low in both groups (RAND-36 Health Survey, 40±4 vs. 33±3, p=0.153),

• Despite more severe fatigue in CFS-POTS patients (CIS fatigue subscale 51±1 vs. 43±3, p=0.016).

• CFS-POTS patients had:

- Greater orthostatic tachycardia than the non-CFS POTS group (51 +/- 3 vs. 40 +/- 4 bpm, p=0.030),

- Greater low frequency variability of blood pressure (6.3+/-0.7 vs. 4.8+/-1.0 mmHg2, p=0.019),

- Greater BP recovery from early to late phase II of the Valsalva maneuver (18+/-3 vs. 11+/-2 mmHg, p=0.041),

- And a higher supine (1.5+/-0.2 vs. 1.0+/-0.3 ng/mL/h; p=0.033) and upright (5.4+/-0.6 vs. 3.5+/-0.8 ng/mL/h; p=0.032) plasma renin activity.

In conclusion:

• Fatigue and CFS-defining symptoms are common in POTS patients. The majority of them met criteria for CFS.

• CFS-POTS patients have higher markers of sympathetic activation but are part of the spectrum of POTS.

• Targeting this sympathetic activation should be considered in the treatment of these patients.

Source: Clinical Science, Sep 12, 2011. DOI:doi:10.1042/CS20110200 by Okamoto LE, Raj SR, Peltier AC, Gamboa A, shibao CA, Dierich A, Black BK, Robertson D, Biaggioni I. Vanderbilt University School of Medicine, Nashville, Tennessee, USA. [Email: Italo.Biaggioni@Vanderbilt.edu]



Please Discuss This Article:   Post a Comment 



[ Be the first to comment on this article ]




 
Free Chronic Fatigue Syndrome and Fibromyalgia Newsletters
Subscribe to
Our FREE
Newsletter
Subscribe Now!
Receive up-to-date ME/CFS & Fibromyalgia treatment and research news
 Privacy Guaranteed  |  View Archives

Save on Vitamins and Supplements

Featured Products

Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
Optimized Curcumin Longvida® by ProHealth Optimized Curcumin Longvida® by ProHealth
Supports Cognition, Memory & Overall Health
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%

Natural Remedies

Irritable Bowel Syndrome: Unlocking the Secrets of Peppermint, Acacia and Fennel Irritable Bowel Syndrome: Unlocking the Secrets of Peppermint, Acacia and Fennel
Magnesium + Malic Acid: One-Two Punch for Pain & Fatigue Magnesium + Malic Acid: One-Two Punch for Pain & Fatigue
Reversing Neurodegeneration with a New Magnesium Compound Reversing Neurodegeneration with a New Magnesium Compound
The Brain Boosting and Fatigue Fighting B-12 The Brain Boosting and Fatigue Fighting B-12
"It's Not Easy Being Green" - But It Is Healthy

FIBROMYALGIA RESOURCES
What is Fibromyalgia?
Fibromyalgia Diagnosis
Fibromyalgia Symptoms
Fibromyalgia Treatments
| CFS RESOURCES
What is CFS?
ME/CFS Diagnosis
ME/CFS Symptoms
ME/CFS Treatments
| FORUMS
Fibromyalgia
ME/CFS
ADVANCED MEDICAL LABS
WHOLESALE  |  AFFILIATES
GUARANTEE  |  PRIVACY
CONTACT US
LIBRARY
RSS
SITE MAP
ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus
Credit Card Processing