ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Is Magnesium the Missing Link in Your Heart Healthy Routine?

A Little Zinc Goes a Long Way

More evidence for calorie restriction’s longevity effect

Supplementation with vitamin D associated with improved testosterone, erectile function among middle...

Vitamin D deficiency increases risk of chronic headache

VIDEO: The Best Brain Foods That Help Increase Your Memory!

Iron (And More) For Lasting, Natural Energy

Get the Most From Your Green Tea

Affordable Care Act made cancer screening more accessible for millions, study finds

Metabolic syndrome increases the need for vitamin E

 
Print Page
Email Article

Vitamin D is often spinal make-or-break factor, surgeons find

  [ 11 votes ]   [ Discuss This Article ]
www.ProHealth.com • November 30, 2011


Article:
Preoperative Vitamin D Status in Adults Undergoing Spinal Fusion
– Source: Paper #45, Nov 3, 2011, North American Spine Society Annual Meeting

By Jacob Buchowski, MD, et al.
 
Abstract:
Background Context: Vitamin D plays a pivotal role in mineral homeostasis and musculoskeletal health. Deficiency in the hormone predisposes to osteoporosis and subsequent fracture.

It can also lead to generalized bone pain and muscle weakness, which may translate into higher VAS, NDI, and ODI scores [visual analogue scale, neck disability index, and Oswestry low back pain disability index].

Recently, 43% of an adult orthopedic surgery population was found to be vitamin D-insufficient preoperatively.

To our knowledge, despite this alarming result, the prevalence of preoperative vitamin D abnormality in a dedicated adult spine surgery population has yet to be investigated.

Purpose:
We sought to characterize the prevalence of preoperative vitamin D inadequacy and deficiency in adults undergoing spinal fusion and to determine whether previously identified risk factors (i.e., black race and obesity) for vitamin D abnormality can be applied to our population.

We also attempted to compare VAS, NDI, and ODI scores between groups of patients with vitamin D inadequacy and normal levels of the metabolite.

Study Design/Setting:
Prospective diagnostic study (Level I).

Patient Sample:
262 consecutive adults who had undergone spinal fusion.

Outcome Measures:
Vitamin D inadequacy or hypovitaminosis D was defined as a serum 25-hydroxyvitamin D (25OHD) level of less than 32 ng/mL, and deficiency was defined as 25OHD less than 20 ng/mL.

Preoperative VAS, NDI, and ODI scores were recorded. Surgical data included the number and location of fused levels.

Methods:
Serum 25OHD levels were measured prospectively in consecutive adults (18 years of age or older) undergoing spinal fusion at a single institution. Operative schedules were surveyed in order to identify these patients. Statistical analysis was performed, and subsets were compared with Fisher’s exact and nonparametric Mann-Whitney U tests. [Used to determine if difference exists between two ‘groups.’]

Results: The mean age and BMI of the population were 55.2 plus/minus 12.9 years and 28.7 plus/minus 5.8 kg/m2, respectively. Of the 262 patients, 55% were female, 94% were white, and 4.6% were black.

There were 44% cervical [neck], 38% thoracic [upper back], and 53% lumbar [lower back] fusions.

The mean vitamin D level was 28.6 plus/minus 13.0 ng/mL. The overall rates of vitamin D inadequacy and deficiency were 65% and 27%, respectively.

As expected, there were significantly higher rates of obesity (BMI plus/minus 30 kg/m2; p=0.025), black race (p=0.005), and smoking (p=0.023) in the vitamin D-inadequate subset.

The mean VAS pain score was higher (p=0.024), bone mineral density was lower (p=0.032), and neurologic deficits were more prevalent (p=0.094) in this group as well.

We generated a composite disability measure by pooling NDI and ODI scores of cervical and thoraco-lumbar patients, respectively.

Upon excluding 57 patients with previous vitamin D or multivitamin supplementation, the mean pooled NDI and ODI score was significantly higher in the inadequate cohort (p=0.003).

Conclusions:


Our investigation revealed an alarmingly high rate of vitamin D abnormality in the analyzed population.

While certain previously identified risk factors were confirmed, validated indices of spine-related disability were higher in the presence of hypovitaminosis D [deficiency].

Since augmenting serum vitamin D is straightforward and inexpensive, and deficiency may predispose to fracture, pseudarthrosis [failure of spinal fusion surgery], and suboptimal surgical outcome, we advocate repletion for patients with documented deficiency.

FDA Device/Drug Status:
This abstract does not discuss or include any applicable devices or drugs.

Source: Paper #45, Nov 3, 2011, North American Spine Society Annual Meeting. Buchowski J, Stoker G, Bridwell K, Lenke L, Riew D, Zebala L. Washington University in St. Louis; Washington University School of Medicine; Washington University Medical Center Department of Orthopedic Surgery; Barnes Jewish Hospital, St. Louis, Missouri, USA. (Reported in North American Spine Society press release, Nov 4: “Watch your back with easy, inexpensive Vitamin D.")





Post a Comment

Featured Products From the ProHealth Store
Vitamin D3 Extreme™ FibroSleep™ Vitamin D3 1000 IU

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products


Article Comments



Be the first to comment on this article!

Post a Comment


 
NAD+ Ignite with Niagen

Featured Products

Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
Vitamin D3 1000 IU Vitamin D3 1000 IU
Crucial nutrient for strong bones, heart and immune health
Vitamin D3 5000 IU Vitamin D3 5000 IU
Give Your Body a Boost With the Sunshine Vitamin
Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength

Natural Remedies

Magnesium + Malic Acid: One-Two Punch for Pain & Fatigue Magnesium + Malic Acid: One-Two Punch for Pain & Fatigue
Curcumin - a Golden Gift of Nature with Benefits Still Untold Curcumin - a Golden Gift of Nature with Benefits Still Untold
Rejuvenating the Brain - How PQQ Helps Power Up Mental Processing Rejuvenating the Brain - How PQQ Helps Power Up Mental Processing
Olea25 Olive Hydroxytyrosol Hits Astonishing 68,000+ ORAC Antioxidant Value Olea25 Olive Hydroxytyrosol Hits Astonishing 68,000+ ORAC Antioxidant Value
Milk Thistle: Trusted Support for Health & Healing in a Toxic World Milk Thistle: Trusted Support for Health & Healing in a Toxic World

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map