ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help

Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Social Anxiety Disorder Linked to High Serotonin Levels, Throwing Treatment with SSRIs into Serious ...

A short-term Borrelia burgdorferi infection model identifies tissue tropisms and bloodstream surviva...

Can Botanicals Beat Brain Fog & Fibrofog?

New Research Substantiates the Anti-Aging Properties of DHEA

Immune response to a flu vaccine yields new insights into narcolepsy

Why WokVel® + Longvida® Makes Sense for FM/CFS Aches & Pains

Children with Lyme Disease

Omega-3 supplements and antioxidants may help with preclinical Alzheimer's disease

Promoting Optimal Nutrition with Digestive Enzymes

7-Keto DHEA The Fat-Burning Metabolite of DHEA

 
Print Page
Email Article

Neurobiology underlying fibromyalgia symptoms – Source: Pain Research and Treatment, Vol 2012

  [ 31 votes ]   [ 1 Comment ]
By Marta Ceko, M Catherine Bushnell, Richard H Gracely • www.ProHealth.com • December 4, 2011


[Note: You may read the free full text of this article, edited by Muhammad B Yunus, at http://www.hindawi.com/journals/prt/2012/585419/.]

Abstract:
Fibromyalgia is characterized by chronic widespread pain, clinical symptoms that include cognitive and sleep disturbances, and other abnormalities such as increased sensitivity to painful stimuli, increased sensitivity to multiple sensory modalities, and altered pain modulatory mechanisms.

Here we relate experimental findings of fibromyalgia symptoms to anatomical and functional brain changes.

• Neuroimaging studies show augmented sensory processing in pain-related areas, which, together with gray matter decreases and neurochemical abnormalities in areas related to pain modulation, supports the psychophysical evidence of altered pain perception and inhibition.

Gray matter decreases in areas related to emotional decision making and working memory suggest that cognitive disturbances could be related to brain alterations.

• Altered levels of neurotransmitters involved in sleep regulation link disordered sleep to neurochemical abnormalities.

Thus, current evidence supports the view that at least some fibromyalgia symptoms are associated with brain dysfunctions or alterations, giving the long-held "it is all in your head" view of the disorder a new meaning.

Source: Pain Research and Treatment, Vol 2012. DOI:10.1155/2012/585419, by Ceko M, Bushnell MC, Gracely RH. Alan Edwards Centre for Research on Pain, Department of Neurology & Neurosurgery, and Department of Anesthesia, McGill University, Montreal, Canada; Center for Neurosensory Disorders, University of North Carolina, Chapel Hill, USA.




Please Discuss This Article:   Post a Comment 

Neurobiology underlying fibromyalgia symptoms
Posted by: ppmickey@gmail.com
Dec 7, 2011
I thank you for your article submitted.
Reply Reply
 
Free Chronic Fatigue Syndrome and Fibromyalgia Newsletters
Subscribe to
Our FREE
Newsletter
Subscribe Now!
Receive up-to-date ME/CFS & Fibromyalgia treatment and research news
 Privacy Guaranteed  |  View Archives

Save on Nutritional Supplement Orders

Featured Products

Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium

Natural Remedies

The Most Powerful Natural Antioxidant Discovered to Date - Hydroxytyrosol The Most Powerful Natural Antioxidant Discovered to Date - Hydroxytyrosol
Vitamin E: Super Antioxidant We Only Thought We Knew Vitamin E: Super Antioxidant We Only Thought We Knew
D-ficient? Health Risks You Need to Know About D-ficient? Health Risks You Need to Know About
SAM-e: a Hard-Working Molecule that May Help Ease Pain & Brighten Mood SAM-e: a Hard-Working Molecule that May Help Ease Pain & Brighten Mood
Complete and Natural Menopause Relief Complete and Natural Menopause Relief

FIBROMYALGIA RESOURCES
What is Fibromyalgia?
Fibromyalgia Diagnosis
Fibromyalgia Symptoms
Fibromyalgia Treatments
| CFS RESOURCES
What is CFS?
ME/CFS Diagnosis
ME/CFS Symptoms
ME/CFS Treatments
| FORUMS
Fibromyalgia
ME/CFS
ADVANCED MEDICAL LABS
WHOLESALE  |  AFFILIATES
GUARANTEE  |  PRIVACY
CONTACT US
LIBRARY
RSS
SITE MAP
ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus
Credit Card Processing