ProHealth health Vitamin and Natural Supplement Store and Health
Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help

|
|
|
|

Trending News

New Science Destroys the Saturated Fat Myth

Diet Affects Men’s and Women’s Gut Microbes Differently

New Lyme guidelines promote options and informed choice

Phases of clinical depression could affect treatment

“Worm pill” could ease autoimmune disease symptoms

Eating Baked or Broiled Fish Weekly Boosts Brain Health, Pitt Study Says

Scientists Look for Biomarkers to Improve Treatment of Painful Bladder Condition

New culprit identified in metabolic syndrome

Low vitamin D levels linked to increased risks after noncardiac surgery

Preserving Cognitive Function with Aging

 
Print Page
Email Article

Both key papers on CFS retroviral involvement retracted, but Lipkin’s virus hunt proceeds

  [ 9 votes ]   [ Discuss This Article ]
www.ProHealth.com • December 27, 2011


A multi-center research team is now searching for evidence of murine gamma retroviruses or other viral involvement in 150 well-defined, geographically diverse chronic fatigue syndrome patient samples. The study, led by Columbia University’s “virus hunter,” Ian Lipkin, and sponsored by the National Institute of Allergy and Infectious Diseases (NIAID) expects to have results some time in 2012.

As Dr. Lipkin has suggested, CFS “smells like a viral disease,” and his lab will be using “next generation” genetic sequencing in the CFS study. (According to him, this technology has allowed identification of 500 new viruses so far.)

Meanwhile, Both the Lo-Alter and Mikovits Papers Have Been Retracted

On December 27, a paper by Shyh-Ching Lo, Harvey Alter, et al. (the Lo, Alter paper), published in August 2010 by the Proceedings of the National Academy of Sciences,(1) has been retracted by the authors. Their paper reported finding human MLV-like retroviruses (members of the XMRV family) in 32 of 37 Chronic Fatigue Syndrome patients and 3 of 44 healthy blood donors.

All the authors signed the retraction statement, noting that their findings have not withstood the test of independent verification. (Still, they also note that they have found no evidence of contamination in their testing materials – and though they believe their previous findings could be reproduced in their own labs, at this point they don’t have enough “original CFS patient samples to do additional testing.”)

This follows news of the December 22 “editorial retraction” by the journal Science of the original October 2009 paper by Mikovits et al., which reported evidence of  XMRV in the blood of many CFS patients and some healthy controls.(2) The editors base their retraction on failure of subsequent studies in other labs to find XMRV in CFS patient samples, and the discovery by two authors of the Science report (at the Cleveland Clinic) of contaminants in materials/samples they used.

Expert Opinions Differ on the Contamination Question

On December 20, Wall Street Journal ME/CFS-tracker Amy Dockser-Marcus reported comments by a number of experts demonstrating that the issue of contamination is far from resolved ("XMRV: Raising the Issue of Contamination"). Tests used to detect XMRV can also detect mouse DNA, and mouse DNA is everywhere in labs. But past studies of XMRV in prostate cancer have found it integrated into patient DNA - and thus hard to explain as contamination.

_____

1. “Detection of MLV-related virus gene sequences in blood of patients with chronic fatigue syndrome and healthy blood donors.”

2. “Detection of an infectious retrovirus, XMRV, in blood cells of patients with chronic fatigue syndrome.”
 



Please Discuss This Article:   Post a Comment 



[ Be the first to comment on this article ]




 
Free Chronic Fatigue Syndrome and Fibromyalgia Newsletters
Subscribe to
Our FREE
Newsletter
Subscribe Now!
Receive up-to-date ME/CFS & Fibromyalgia treatment and research news
 Privacy Guaranteed  |  View Archives

Save on Your Next Order

Featured Products

Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
FibroSleep™ by ProHealth FibroSleep™ by ProHealth
The All-in-One Natural Sleep Aid
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
Optimized Curcumin Longvida® by ProHealth Optimized Curcumin Longvida® by ProHealth
Supports Cognition, Memory & Overall Health
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function

Natural Remedies

Running on Empty? Fuel Up with NADH Running on Empty? Fuel Up with NADH
The Brain Boosting and Fatigue Fighting B-12 The Brain Boosting and Fatigue Fighting B-12
Anti-Inflammatory Properties of Tart Cherry Anti-Inflammatory Properties of Tart Cherry
Front Line Defense Against Colds & Flu - Support for Healthy Immune System Balance Front Line Defense Against Colds & Flu - Support for Healthy Immune System Balance
The Big Blue Fish that Helps Chase the Blues Away The Big Blue Fish that Helps Chase the Blues Away

FIBROMYALGIA RESOURCES
What is Fibromyalgia?
Fibromyalgia 101
Fibromyalgia Symptoms
Fibromyalgia Treatments
| CFS RESOURCES
What is CFS?
ME/CFS 101
ME/CFS Symptoms
ME/CFS Treatments
| FORUMS
Fibromyalgia
ME/CFS
ADVANCED MEDICAL LABS
WHOLESALE  |  AFFILIATES
GUARANTEE
CONTACT US
PRIVACY
RSS
SITE MAP
ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus
Credit Card Processing