ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Is Magnesium the Missing Link in Your Heart Healthy Routine?

More evidence for calorie restriction’s longevity effect

A Little Zinc Goes a Long Way

Supplementation with vitamin D associated with improved testosterone, erectile function among middle...

Vitamin D deficiency increases risk of chronic headache

VIDEO: The Best Brain Foods That Help Increase Your Memory!

Get the Most From Your Green Tea

Iron (And More) For Lasting, Natural Energy

Metabolic syndrome increases the need for vitamin E

Supplement combo improves bone density, mood, in postmenopausal women

 
Print Page
Email Article

Fibromyalgia-like pain as a cause of autonomic dysregulation

  [ 16 votes ]   [ Discuss This Article ]
www.ProHealth.com • January 30, 2012


Article:
Induction of chronic non-inflammatory widespread pain increases cardiac sympathetic modulation in rats
- Source: Autonomic Neuroscience, Jan 21, 2012

By LR Oliveira, VJ Santana-Filho, et al.

[Note: The autonomic nervous system works below the level of consciousness to maintain the body’s balance – regulating blood pressure, pulse, breathing rates, etc. as needed in response to changing physical demands. Two parts of the system are sympathetic function, which involves ‘pushing’, balanced by parasympathic function, which involves relaxing. One type of autonomic dysregulation is when heart rate increases and blood pressure/volume decreases abnormally on standing, causing faint feeling (postural orthostatic tachycardia syndrome - POTS).]

Abstract:
Fibromyalgia (FM) is characterized by chronic non-inflammatory widespread pain (CWP) and changes in sympathetic function. In attempt to elucidate the pathophysiological mechanisms of FM we used a well-established CWP animal model.

We aimed to evaluate changes in cardiac autonomic balance and baroreflex function in response to CWP induction in rats. [Baroreflex function refers to the body’s mechanism for maintaining blood pressure.] CWP was induced by two injections of acidic saline (pH 4.0, n=8) five days apart into the left gastrocnemius muscle. Control animals were injected twice with normal saline (pH 7.2, n=6).

One day after the second injection of acidic saline or normal saline, the animals had pulse interval (PI) and systolic arterial pressure (SAP) variability, and spontaneous baroreflex sensitivity (BRS) evaluated.

After induction of CWP, there was an increase of power in the low frequency (LF) band of PI spectrum (12.75±1.04nu), a decrease in the high frequency (HF) band (87.25±1.04nu) and an increase of LF/HF ratio (0.16±0.01), when compared to control animals (7.83±1.13nu LF; 92.16±1.13nu HF; 0.08±0.01 LF/HF).

In addition, there was an increase of power in the LF band of SAP spectrum (7.93±1.39mmHg(2)) when compared to control animals (2.97±0.61mmHg(2)). BRS was lower in acidic saline injected rats (0.59±0.06ms/mmHg) when compared to control animals (0.71±0.03ms/mmHg).

Our results showed that induction of chronic widespread pain in rats shifts cardiac sympathovagal balance towards sympathetic [pushing] predominance and decreases BRS [blood pressure/flow]. These data corroborate findings in humans with FM.

Source: Autonomic Neuroscience, Jan 21, 2012. Department of Physiology, Federal University of Sergipe, Sao Cristovao, Brazil; Graduate Program in Physical Therapy and Rehabilitation Science, University of Iowa, Iowa City, USA. [Email: visf@infonet.com.br]





Post a Comment

Featured Products From the ProHealth Store
Vitamin D3 Extreme™ Ultra EPA  - Fish Oil FibroSleep™

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products


Article Comments



Be the first to comment on this article!

Post a Comment


 
NAD+ Ignite with Niagen

Featured Products

Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium

Natural Remedies

Complete and Natural Menopause Relief Complete and Natural Menopause Relief
Health Benefits Are Brewing in Green Tea Health Benefits Are Brewing in Green Tea
Sunshine Vitamin Has D-lightful Health Benefits Sunshine Vitamin Has D-lightful Health Benefits
Physically and Mentally Exhausted? How to Restore Energy at Its Source Physically and Mentally Exhausted? How to Restore Energy at Its Source
The Surprising Benefits of Probiotics - What You Didn't Know The Surprising Benefits of Probiotics - What You Didn't Know

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map