ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Ultrasound Therapy for Fibromyalgia and Lyme Disease

Curcumin: The All In One Solution, Part 2

What Are the Benefits of Vitamin K2?

Vitamin D deficiency + high fat diet = metabolic syndrome

Why You Should Take Your Apple Cider Vinegar at Night

Use Burdock Oil to Promote Healthy Hair Growth

People with forms of early-onset Parkinson's disease may benefit from boosting niacin in diet, resea...

Meet Your Weight Loss Goals

AMA journal associates iron deficiency with hearing loss

Why the Mediterranean Diet Is so Successful

 
Print Page
Email Article

Fibromyalgia-like pain as a cause of autonomic dysregulation

  [ 16 votes ]   [ Discuss This Article ]
www.ProHealth.com • January 30, 2012


Article:
Induction of chronic non-inflammatory widespread pain increases cardiac sympathetic modulation in rats
- Source: Autonomic Neuroscience, Jan 21, 2012

By LR Oliveira, VJ Santana-Filho, et al.

[Note: The autonomic nervous system works below the level of consciousness to maintain the body’s balance – regulating blood pressure, pulse, breathing rates, etc. as needed in response to changing physical demands. Two parts of the system are sympathetic function, which involves ‘pushing’, balanced by parasympathic function, which involves relaxing. One type of autonomic dysregulation is when heart rate increases and blood pressure/volume decreases abnormally on standing, causing faint feeling (postural orthostatic tachycardia syndrome - POTS).]

Abstract:
Fibromyalgia (FM) is characterized by chronic non-inflammatory widespread pain (CWP) and changes in sympathetic function. In attempt to elucidate the pathophysiological mechanisms of FM we used a well-established CWP animal model.

We aimed to evaluate changes in cardiac autonomic balance and baroreflex function in response to CWP induction in rats. [Baroreflex function refers to the body’s mechanism for maintaining blood pressure.] CWP was induced by two injections of acidic saline (pH 4.0, n=8) five days apart into the left gastrocnemius muscle. Control animals were injected twice with normal saline (pH 7.2, n=6).

One day after the second injection of acidic saline or normal saline, the animals had pulse interval (PI) and systolic arterial pressure (SAP) variability, and spontaneous baroreflex sensitivity (BRS) evaluated.

After induction of CWP, there was an increase of power in the low frequency (LF) band of PI spectrum (12.75±1.04nu), a decrease in the high frequency (HF) band (87.25±1.04nu) and an increase of LF/HF ratio (0.16±0.01), when compared to control animals (7.83±1.13nu LF; 92.16±1.13nu HF; 0.08±0.01 LF/HF).

In addition, there was an increase of power in the LF band of SAP spectrum (7.93±1.39mmHg(2)) when compared to control animals (2.97±0.61mmHg(2)). BRS was lower in acidic saline injected rats (0.59±0.06ms/mmHg) when compared to control animals (0.71±0.03ms/mmHg).

Our results showed that induction of chronic widespread pain in rats shifts cardiac sympathovagal balance towards sympathetic [pushing] predominance and decreases BRS [blood pressure/flow]. These data corroborate findings in humans with FM.

Source: Autonomic Neuroscience, Jan 21, 2012. Department of Physiology, Federal University of Sergipe, Sao Cristovao, Brazil; Graduate Program in Physical Therapy and Rehabilitation Science, University of Iowa, Iowa City, USA. [Email: visf@infonet.com.br]





Post a Comment

Featured Products From the ProHealth Store
Vitamin D3 Extreme™ Ultra EPA  - Fish Oil Energy NADH™ 12.5mg

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products


Article Comments



Be the first to comment on this article!

Post a Comment


 
NAD+ Ignite with Niagen

Featured Products

FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium

Natural Remedies

Coconut Oil - Healthy Gifts from the 'Tree of Life' Coconut Oil - Healthy Gifts from the 'Tree of Life'
Vitamin K-2 – A Key Player in Cardiovascular and Bone Health Vitamin K-2 – A Key Player in Cardiovascular and Bone Health
Coping When Colds or Flu Catch Up with You Coping When Colds or Flu Catch Up with You
Natural Support for Mood, Sleep and Mental Focus? L-theanine Natural Support for Mood, Sleep and Mental Focus? L-theanine
Restoring Gut Health: How to Create a Firewall Against Toxins Entering the Gut Wall Restoring Gut Health: How to Create a Firewall Against Toxins Entering the Gut Wall

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map