ProHealth health Vitamin and Natural Supplement Store and Health
Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help

|
|
|
|
 
Print Page
Email Article

Celiac Disease and Hypothyroidism - Source: American Journal of Medicine, Mar 2012

  [ 5 votes ]   [ 1 Comment ]
By Dan Colins, Richard Zubarik, et al. • www.ProHealth.com • March 19, 2012

previous article next article

Background: Celiac disease is more common in patients with hypothyroidism. Malabsorption of levothyroxine has not been studied in this population. We sought to determine if levothyroxine dosing was influenced by the presence and treatment of celiac disease.

Methods: This retrospective study was conducted at an academic medical center.

• Cases had hypothyroidism and celiac disease.

• Controls had hypothyroidism alone, and were selected randomly through the endocrinology clinic records.

Celiac disease was defined as representative pathology with positive serology. Age, sex, height, weight, body mass index, creatinine, and medical comorbidity were assessed for cases and controls. The levothyroxine dose and weight-based levothyroxine dose necessary to maintain a euthyroid state [normal thyroid level] was evaluated:

• For controls,

• And before and after celiac disease therapy [e.g., gluten-free diet] for cases.

Results: Celiac disease was identified in 152 patients, and 22 patients had concomitant hypothyroidism (14.5%). Seven cases met inclusion criteria. Overall, 200 control patients were identified.

• The mean celiac disease pretreatment levothyroxine dose and weight-based levothyroxine dose needed to maintain a euthyroid state [normal thyroid level] were higher in cases than in controls (154 micrograms vs 106 micrograms, P = .007, and 2.6 micrograms vs 1.3 micrograms, P <.001).

• Doses decreased significantly after treatment of celiac disease (154 micrograms vs 111 micrograms, P = .03; and 2.64 micrograms/kg vs 1.89 micrograms/kg, P = .04).

• All cases [hypothyroid with celiac disease, before treatment] required at least 125 micrograms of levothyroxine initially to maintain a euthyroid state.

Conclusions:


• Levothyroxine malabsorption likely occurs with hypothyroidism and untreated celiac disease.

• Absorption may improve after celiac disease treatment.

• Screening for celiac disease in patients with hypothyroidism requiring elevated levothyroxine doses warrants further investigation.

Source: American Journal of Medicine, Mar 2012;125(3);278-282. By Collins D, Wilcox R, Hathan M, Zubarik R. Departments of Medicine, Pathology, Endocrinology and Gastroenterology, University of Vermont, Fletcher-Allen Health Care, Burlington, Vermont, USA. [Email: richard.zubarik@vtmednet.org]



previous article
  Rating 5 (5 votes) next article




DISCUSS THIS ARTICLE   (1 existing comment) Post a Comment 


Gluten Free Girl Scout cookies
Posted by: StacyIM
Mar 25, 2012
Please support my petition for the Girl Scouts to sell a gluten free and allergen free cookie. http://www.change.org/petitions/encourage-the-girl-scouts-to-sell-an-allergen-free-cookie
Reply Reply
 
Free Chronic Fatigue Syndrome and Fibromyalgia Newsletters
Subscribe to
Our FREE
Newsletter
Subscribe Now!
Receive up-to-date ME/CFS & Fibromyalgia treatment and research news
 Privacy Guaranteed  |  View Archives

Save on Your Next Order

Featured Products
FibroSleep™ by ProHealth FibroSleep™ by ProHealth
The All-in-One Natural Sleep Aid
Vitamin D3 5000 IU Vitamin D3 5000 IU
Give your body a boost with the sunshine vitamin
Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength
Natural Resveratrol Natural Resveratrol
Powerful Antioxidant Support + Positive Anti-aging Effects
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils

Most Viewed Articles
What's the Hidden Cause Behind YOUR Fibromyalgia Flares? [more]

Pridgen Reports Fibromyalgia Antiviral Trial Results “Very Positive”: Predicts New Approach Will Be ... [more]

VIDEO: IACFS/ME Conference - Summary of Research by Dr. Komaroff [more]

How to Limit or Minimize Your Fibromyalgia Flare [more]

Mitochondrial Dysfunction, Post-Exertional Malaise and CFS/ME [more]

The Devil Is In The Details – A Herpes Simplex Virus Inquiry For Fibromyalgia and Chronic Fatigue Sy... [more]

Sympathetic Nervous System Dysfunction in FIbromyalgia and Overlapping Conditions [more]

Review of Nutritional Supplements Used for ME/CFS and FM [more]

FREE: Stop Feeding Yourself PAIN Guide [more]

Sympathetic nervous system dysfunction in fibromyalgia, chronic fatigue syndrome, irritable bowel sy... [more]


FIBROMYALGIA RESOURCES
What is Fibromyalgia?
Fibromyalgia 101
Fibromyalgia Symptoms
Fibromyalgia Treatments
| CFS RESOURCES
What is CFS?
ME/CFS 101
ME/CFS Symptoms
ME/CFS Treatments
| FORUMS
Fibromyalgia
ME/CFS
ADVANCED MEDICAL LABS
WHOLESALE  |  AFFILIATES
GUARANTEE
CONTACT US
PRIVACY
RSS
SITE MAP
ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus
Credit Card Processing