ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Fighting Heartburn and Gerd Naturally – And Safely!

Vital Molecule Increases Cellular Energy and Improves Cognitive Function

Natural Bladder Control, Go Less and Live More

Top Vitamin and Mineral Deficiencies — Are You at Risk?

Trimming the spare tire: Canola oil may cut belly fat

How Pomegranate May Protect Against Cancer

Omega Fix for Obesity: How the Right Fats Fight Fat

Curcumin Reverses the Cellular Damage of Chronic Stress

Probiotics improve cognition in Alzheimer's patients

The Onion: Cancer Fighter and Food Preserver

 
Print Page
Email Article

Strong Evidence of a Genetic Link in Fibromyalgia

  [ 63 votes ]   [ 2 Comments ]
www.ProHealth.com • January 4, 2013


Strong Evidence of a Genetic Link in FibromyalgiaArticle:

The fibromyalgia family study: A genome-scan linkage study.

– Source:  Arthritis and Rheumatism, December 28, 2012. [Epub ahead of print]

By Lesley M. Arnold, et al.



Abstract:

Objective:  Familial aggregation of fibromyalgia has been increasingly recognized. The goal of the current study was to conduct a genome wide linkage scan to identify susceptibility loci for fibromyalgia.

Methods:  We genotyped members of 116 families from the Fibromyalgia Family Study and performed a model-free genome-wide linkage analysis of fibromyalgia with 341 microsatellite markers, using the Haseman-Elston regression approach.

Results:  The estimated sibling recurrence risk ratio (?(s) ) for fibromyalgia was 13.6 (95% CI: 10.0-18.5), based on a reported population prevalence of 2%. Genome-wide suggestive evidence of linkage was found at marker D17S2196 (Empirical P =0.00030) and D17S1294 (Empirical P =0.00035) on chromosome 17p11.2-q11.2.

Conclusion:  The estimated sibling recurrence risk ratio suggests a strong genetic component of fibromyalgia.

This is the first study to report genome-wide suggestive linkage of fibromyalgia to the chromosome 17p11.2-q11.2 region.

Further investigation of these multi-case families from the Fibromyalgia Family Study is warranted to identify potential causal risk variants for fibromyalgia. © 2012 American College of Rheumatology.

Source:  Arthritis and Rheumatism, December 28, 2012. [Epub ahead of print]. By Lesley M. Arnold, I. Jon Russell, Muhammad B. Yunus, M.A. Khan, I. Kushner, J.M. Olson, S.K. Iyengar. Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati College of Medicine, Cincinnati, Ohio. E-mail: Lesley.Arnold@uc.edu.





Post a Comment

Featured Products From the ProHealth Store
FibroSleep™ Ultra ATP+, Double Strength Mitochondria Ignite™ with NT Factor®


Article Comments Post a Comment

nice to know
Posted by: roge
Jan 4, 2013
genetic link was highly suspected for years and good to get more confirmation but researchers what are you doing to help better treat this horrible disease and gain a better understanding of the pathology . I can assure everyone with FM would rather have that answered then if this runs in families - can we please get come priority setting here with regards to how research dollars are spent here - man o man.
Reply Reply

"Genetic link?" I hope to shout!
Posted by: tursiops
Jan 16, 2013
I got sick in June 1981, at age 42. My daughter got sick several years later, at age 34. Within a year, she was no longer
able to work.
Recently, she has in addition, been diagnosed with MS.

My son, a few years later, came down with it too, he was 42.

And can anybody help me get the full spectrum of tests for hypo-
thyrodism? My doctor absolutely REFUSES to do anything but the
THS test,citing it as the most 'sensitive.' Everything I've read
about it shows that, if you don't know the results of the T3, T4
tests, you aren't getting the full picture. And, given that I am
a tall, plus size lady, does the dosage for thyroid replacement
for a 5' tall, 98 pound person seem adequate for someone larger?
I have taken him articles written by doctors, for doctors, and
he won't even read them. Why do I keep him as my PCP? I live in
a rural area. Only choice.
Reply Reply
 
Natural Pain Relief Supplements

Featured Products

Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength

Natural Remedies

The Big Blue Fish that Helps Chase the Blues Away The Big Blue Fish that Helps Chase the Blues Away
When a Negative is Positive - Goodnighties Recovery Sleepwear When a Negative is Positive - Goodnighties Recovery Sleepwear
Restore Youthful Cognition and Well-Being Restore Youthful Cognition and Well-Being
Eating Fat is Good... Maybe... Could Be... Sometimes Eating Fat is Good... Maybe... Could Be... Sometimes
Optimize Your Immune System Naturally: Thymic Protein A Optimize Your Immune System Naturally: Thymic Protein A

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2016 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map