Activate Now
ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

For veterans with Gulf War Illness, an explanation for the unexplainable symptoms

Acupuncture reduces hot flashes in breast cancer survivors

SURVEY: Has Your Illness Affected What You Eat?

DePaul Study Recruiting Participants

Recent Research on Gulf War illness and other health problems in veterans of the 1991 Gulf War: Effe...

Cocoa flavanols lower blood pressure and increase blood vessel function in healthy people

Mediterranean Diet Plus Olive Oil Associated with Reduced Breast Cancer Risk

Chemical exposure linked to rising diabetes, obesity risk

Researchers find 'dormant' parasite cysts are actually quite active

Resveratrol impacts Alzheimer's disease biomarker

Print Page
Email Article

Low levels of vitamin D are associated with neuropathy and lymphoma among patients with Sjögren’s Syndrome

  [ 3 votes ]   [ Discuss This Article ] • May 1, 2013

 Editor’s Comment: Sicca, or dry eyes and mouth, is included in both the Canadian and International case definitions for CFS/ME. In 1996, researchers in Japan found that fully one-third of the CFS/ME patients met the diagnostic criteria for Sjögren's.

Novel aspects of Sjögren’s syndrome in 2012

By Angela Tincani et al. 


Sjögren’s syndrome (SS) is a systemic progressive autoimmune disease characterized by a complex pathogenesis requiring a predisposing genetic background and involving immune cell activation and autoantibody production. The immune response is directed to the exocrine glands, causing the typical ‘sicca syndrome’, but major organ involvement is also often seen. 

The etiology of the disease is unknown. Infections could play a pivotal role: compared to normal subjects, patients with SS displayed higher titers of anti-Epstein-Barr virus (EBV) early antigens, but lower titers of other infectious agent antibodies such as rubella and cytomegalovirus (CMV) suggest that some infections may have a protective role against the development of autoimmune disease. 

Recent findings seem to show that low vitamin D levels in patients with SS could be associated with severe complications such as lymphoma and peripheral neuropathy. This could open new insights into the disease etiology. 

The current treatments for SS range from symptomatic therapies to systemic immunosuppressive drugs, especially B cell-targeted drugs in cases of organ involvement. Vitamin D supplementation may be an additional tool for optimization of SS treatment.

Source: BMC Medicine 2013, 11:93 doi:10.1186/1741-7015-11-93. Angela Tincani, Laura Andreoli2, Ilaria Cavazzana1, Andrea Doria, Marta Favero, Maria-Giulia Fenini, Franco Franceschini, Andrea Lojacono, Giuseppe Nascimbeni, Amerigo Santoro, Francesco Semeraro, Paola Toniati and Yehuda Shoenfeld. 

Please Discuss This Article:   Post a Comment 

[ Be the first to comment on this article ]

Free Chronic Fatigue Syndrome and Fibromyalgia Newsletters
Subscribe to
Subscribe Now!
Receive up-to-date ME/CFS, Fibromyalgia & Lyme Disease treatment and research news
 Privacy Guaranteed  |  View Archives

Vitamins and Supplements

Featured Products

Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium

Natural Remedies

Nutrients to Combat the Modern Stress Epidemic Nutrients to Combat the Modern Stress Epidemic
Carry a Massage Therapist in Your Pocket Carry a Massage Therapist in Your Pocket
Optimize Your Immune System Naturally: Thymic Protein A Optimize Your Immune System Naturally: Thymic Protein A
Are You Obtaining the Proper Enzymes? Are You Obtaining the Proper Enzymes?
"It's Not Easy Being Green" - But It Is Healthy

What is Fibromyalgia?
Fibromyalgia Diagnosis
Fibromyalgia Symptoms
Fibromyalgia Causes
Fibromyalgia Treatments
Fibromyalgia Diet
Fibromyalgia Medications
M.E. & CFS
What is M.E./CFS?
M.E./CFS Diagnosis
M.E./CFS Symptoms
M.E./CFS Causes
M.E./CFS Treatments
M.E./CFS Diet
M.E./CFS Medications
What is Lyme Disease?
Lyme Disease Diagnosis
Lyme Disease Symptoms
Lyme Disease Causes
Lyme Disease Treatments
Lyme Disease Diet
Lyme Disease Medications
M.E. & CFS
Lyme Disease
General Health
ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus
Credit Card Processing