ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help

|
|
|
|

Trending News

Magnesium: An Invisible Deficiency That Could Be Harming Your Health

Fatigue & Fibro Fog: Could You Have a B-12 Deficiency?

“Next Generation” Vitamin Provides Hope To Aging Societies Worldwide

Advances in Understanding of Depression Offers New Hope

Resolved to lose weight in 2015? Here are five bad strategies to avoid

Safely Burn Away Body Fat

Vitamin K1 and K2—Two Underappreciated Nutrients That Are Crucial for Health

Make a New Year's resolution to manage your diabetes

Year of birth significantly changes impact of obesity-associated gene variant

Curcumin's ability to fight Alzheimer's studied

 
Print Page
Email Article

K-PAX Pharmaceuticals and Stanford University to Collaborate on Clinical Trial to Study New Treatment for Chronic Fatigue Syndrome

  [ 11 votes ]   [ 1 Comment ]
www.ProHealth.com • March 5, 2014


K-PAX Pharmaceuticals and Stanford University to Collaborate on Clinical Trial to Study New Treatment for Chronic Fatigue Syndrome
MILL VALLEY, Calif., Feb. 26, 2014 /PRNewswire/ -- K-PAX Pharmaceuticals is working with Stanford University and several other leading research institutions to perform a Phase II double-blind, placebo-controlled trial to evaluate the safety and efficacy of a currently available FDA-approved medication concurrently administered with a novel mitochondrial support product in order to identify a safe and effective treatment for the chronic fatigue and decreased alertness (i.e. brain fog) that commonly afflicts people with CFS.

The Synergy Trial (http://thesynergytrial.org) will enroll 120 subjects at four research sites throughout the United States. It is the largest double-blind, placebo-controlled pharmaceutical intervention trial in people with CFS to date. In addition to Stanford University, the other research sites include Salt Lake City, New York City, and Nova Southeastern University in Fort Lauderdale, Florida.

This randomized clinical trial will test a combination of a low-dose CNS stimulant (methylphenidate - a generic version of Ritalin®) co-administered with a CFS mitochondrial support formula. This nutrient formula is a broad-spectrum micronutrient supplement designed to provide therapeutic dosages of key nutrients that support the functioning of the nervous, endocrine, and immune systems to a level at which concomitantly administered methylphenidate can produce a positive effect on CFS symptoms.

When this treatment was previously administered to 15 prospectively recruited patients as innovative therapy, it produced encouraging results resulting in a significant improvement in both fatigue and concentration disturbance symptoms (i.e. brain fog) as measured by the Checklist Individual Strength (CIS), a validated research tool used to assess fatigue in patients with Chronic Fatigue Syndrome. This improvement occurred in greater than 50% of the CFS patients after just 12 weeks.  Based upon these results, K-PAX Pharmaceuticals is pursuing further investigation of this potentially promising therapy.

Chronic Fatigue Syndrome (CFS) is a debilitating disease that currently affects over 2 million Americans and has no FDA-approved treatments. The FDA has identified CFS as "a serious unmet medical need" and specifically requested that pharmaceutical companies search for a safe and effective treatment.

K-PAX Pharmaceuticals, based in Mill Valley, California, is a privately-held biotechnology company pioneering medicines to strengthen immune function and support optimal energy metabolism. Learn more here.
 


Please Discuss This Article:   Post a Comment 

Synergy Trial
Posted by: me/cfs
Mar 6, 2014
This appears to be a promising avenue to the first FDA approval for ME/CFS treatment.

They had promising preliminary results, it is a large multi-site study being carried out by leading ME/CFS researchers and it is an attempt to address concerns with immune, endocrine, and mitochondrial function.

My question to K-PAX would be, have they tried their micronutrients with other pharmaceuticals (besides methylphenidate)? One that I would be curious about would be an antihistamine known as hydroxyzine.

Best hopes for all involved.
Reply Reply
 
Free Chronic Fatigue Syndrome and Fibromyalgia Newsletters
Subscribe to
Our FREE
Newsletter
Subscribe Now!
Receive up-to-date ME/CFS & Fibromyalgia treatment and research news
 Privacy Guaranteed  |  View Archives

Save on Vitamins and Supplements

Featured Products

Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
Vitamin D3 Extreme™ by ProHealth Vitamin D3 Extreme™ by ProHealth
50,000 IU Vitamin D3 - Prescription Strength
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
Optimized Curcumin Longvida® by ProHealth Optimized Curcumin Longvida® by ProHealth
Supports Cognition, Memory & Overall Health
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium

Natural Remedies

Repair Damaged Mitochondria and Reduce Fatigue Up to 45% Repair Damaged Mitochondria and Reduce Fatigue Up to 45%
The Big Blue Fish that Helps Chase the Blues Away The Big Blue Fish that Helps Chase the Blues Away
Why Berries Offer a Rainbow of Health Benefits Why Berries Offer a Rainbow of Health Benefits
The Revolutionary 'Good Fat' That Promotes Heart, Brain, Bone and Joint Health The Revolutionary 'Good Fat' That Promotes Heart, Brain, Bone and Joint Health
"It's Not Easy Being Green" - But It Is Healthy

FIBROMYALGIA RESOURCES
What is Fibromyalgia?
Fibromyalgia Diagnosis
Fibromyalgia Symptoms
Fibromyalgia Treatments
| CFS RESOURCES
What is CFS?
ME/CFS Diagnosis
ME/CFS Symptoms
ME/CFS Treatments
| FORUMS
Fibromyalgia
ME/CFS
ADVANCED MEDICAL LABS
WHOLESALE  |  AFFILIATES
GUARANTEE  |  PRIVACY
CONTACT US
LIBRARY
RSS
SITE MAP
ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus
Credit Card Processing