Activate Now
 
ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Patient Insights into the Design of Technology to Support a Strengths-Based Approach to Health Care.

Greater intake of dietary omega-3 fatty acids associated with lower risk of diabetic retinopathy

SURVEY: Weight Management & Chronic Illness

Japanese green tea consumers have reduced risk of dementia

Researchers find herpes strain in the nervous system

Do Nothing, Accomplish Everything! The Connection Between Breathing and Healing

Nature Heals

Choline: Why You Should Eat Your Egg Yolks and Take Krill

Calcium, vitamin D supplementation associated improved stroke recovery

Best Herbs to Help With Insomnia

 
Print Page
Email Article

Relationship of thyroid dysfunction to Chronic Fatigue Syndrome

  [ 77 votes ]   [ Discuss This Article ]
By Action For M.E. • www.ProHealth.com • February 13, 2001


Editor’s Note: This article is reproduced with permission from InterAction magazine, the quarterly publication from the UK charity, Action for M.E. To find out more about support services provided by Action for M.E. to sufferers and their carers, please send email to london@afme.org.uk or mail a self-addressed stamped envelope to Action for M.E., PO Box 1302,Wells, Somerset BA5 1YE, or telephone 01749 670799.

Purpose

The purpose of this study was to evaluate the response to thyroid replacement therapy in patients considered to be suffering from underactive thyroid because of their presenting signs and symptoms, but whose thyroid biochemistry (i.e. blood test results) were within ‘normal’ laboratory reference ranges.

Presenting signs and symptoms of hypothyroidism include:
* Loss of energy, tiredness, lethargy or exhaustion
* Poor memory or concentration or ‘fuzzy head’
* Changes in skin (dry and flaky), hair (fine, coarse, thinning) or voice (deeper)
* Muscle or joint pain
* Constipation and/or bloated stomach
* Cold or heat intolerance
* Enlarged thyroid gland

Design

Practice-based open interventions study; control group used for baseline laboratory values only.

Methods

The 139 patients studied who presented with the 16 recognised criteria of clinical hypothyroidism had been diagnosed with a range of different conditions: 64 with ME/CFS/PVFS, 32 with depression and 43 with other diagnoses, although these prior diagnoses are mentioned for interest only.
All patients were given 25mcg a day thyroxine sodium for the first week, building up by 25mcg at six week intervals until patient was clinically euthyroid (in optimum health' with normal thyroid chemistry) Response to treatment was assessed on how many clinical signs and symptoms of hypothyroidism disappeared or improved (usually 6-12 months).

Results
* In 22% of the patients all 16 clinical features of hypothyroidism either disappeared or improved.
* Patients FT4 (thyroid level) blood test results were averaging 13.2 prior to treatment but after treatment, when many signs and symptoms had improved, they were averaging 18.4.
* Likewise, TSH (thyroid stimulating hormone) blood test results were averaging 2.3 prior to treatment, but after treatment when many signs and symptoms had disappeared or improved, they were averaging 0.35. [the TSH has to work harder if there is less thyroid hormone available – Ed].
* Of the 139 patients studied, 129 (93%) had disappearance or improvement of at least 10 of the signs and symptoms. 93% of the study patients showed a remarkable improvement in their health, subjectively.

Comment

The study shows that the majority of patients, judged to be hypothyroid because of presenting signs and symptoms despite ‘normal’ blood test results, responded well to thyroid replacement therapy.

From the Journal of Nutritional and Environmental Medicine, as part of the study write-up:

‘In the absence of a control group, a placebo effect cannot be excluded in this or any other study. However, the average duration of illness was 7.5 years in patients who had usually undergone an alarming array of traditional and alternative medications without significant improvement as evidenced by their wish to seek further medical advice. Secondly, certain clinical features allowed objective assessment, namely changed in appearance, hair or skin texture, reduction in size of tongue and thyroid gland and increase in pulse rate. Therefore, while acknowledging the criticality of such a formal clinical trial – and indeed we are pleased to report that such a trial has been instituted at Stobhill Hospital, Glasgow – the proposition of placebo effect to explain sustained clinical response in 135 of 139 patients is unlikely.’

Dr Ellen Goudsmit comments:
‘This paper should be interpreted with care. The study does not relate specifically to CFS, but to people with chronic fatigue and symptoms of hypothyroidism. Some individuals with borderline values may be helped by thyroid supplementation but this should be supervised by an expert, with lots of experience.'

Clinical Response to Thyroxine Sodium in Clinically Hypothyroid but Biochemically Euthyroid Patients, Skinner G, Holmes D et al. Journal of Nutritional and Environmental Medicine. (2000) 10, 115-124



Post a Comment

Featured Products From the ProHealth Store
Energy NADH™ 12.5mg Mitochondria Ignite™ with NT Factor® Ultra EPA  - Fish Oil

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products


Article Comments



Be the first to comment on this article!

Post a Comment


 
Natural Pain Relief Supplements

Featured Products

Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium

Natural Remedies

Are You Obtaining the Proper Enzymes? Are You Obtaining the Proper Enzymes?
Safely Burn Away Body Fat Safely Burn Away Body Fat
Everything You Always Wanted to Know About Sleep But Were Too Tired to Ask Everything You Always Wanted to Know About Sleep But Were Too Tired to Ask
Block Acid Reflux to Prevent Esophageal Problems! Block Acid Reflux to Prevent Esophageal Problems!
How I Found My Long-Lost Energy How I Found My Long-Lost Energy

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE AND SAVE 15% NOW*
Be the first to know about new products, special discounts and the latest health news. *New subscribers only

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2016 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map