ProHealth health Vitamin and Natural Supplement Store and Health
Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help

|
|
|
|

Trending News

Missing protein explains link between obesity, diabetes

The Brain Boosting and Fatigue Fighting B-12

Genetic basis for distinct type of autism uncovered

Unsuspected aspect of immune regulation revealed: Role of B cells

IBS, Crohn’s Disease, Colitis, and Other Digestive Disorders

Sinus Congestion and Sinusitis, Healing Naturally

Explaining 'Healthy' Obesity

New Science Destroys the Saturated Fat Myth

Ginger's Many Evidence-Based Health Benefits Revealed

Omega 3 Fatty Acids Lessen Severity of Osteoarthritis in Mice

 
Print Page
Email Article

Pain as a key neuro-immune symptom of ME/CFS & the need for treatments

  [ 70 votes ]   [ Discuss This Article ]
www.ProHealth.com • September 22, 2012


Article:
Pain in Patients with Chronic Fatigue Syndrome: Time for Specific Pain Treatment?
- Source: Pain Physician, Sep-Oct 2012

[Note: Studies indicate 94% of ‘chronic fatigue syndrome’ (ME/CFS) patients suffer with muscle pain, 84% joint pain, and 80% headache - and pain is a key factor in disability levels. The full text of this report summarizing current knowledge regarding the nature and importance of pain in ME/CFS is available free at http://www.painphysicianjournal.com/2012/september/2012;15;E677-E686.pdf.

Abstract:
Background:

• Besides chronic fatigue, patients with chronic fatigue syndrome (CFS) have debilitating widespread pain.

• Yet pain from CFS is often ignored by clinicians and researchers.

Objectives:

• To examine whether pain is a unique feature of CFS, or does it share the same underlying mechanisms as other CFS symptoms?

• Second, it is examined whether effective treatments for pain from CFS are currently available.

Study Design: Narrative review covering the scientific literature up through December 2011.

Setting: Several universities.

Results: From the available literature:

• It is concluded that musculoskeletal factors [muscle/bone disorder or trauma] are unlikely to account for pain from CFS.

• Pain seems to be one out of many symptoms related to central sensitization from CFS.

This idea is supported by the findings of:

• Generalized hyperalgesia (including widespread increased responsiveness to painful stimuli)

• And dysfunctional endogenous analgesia in response to noxious thermal stimuli.

Pain catastrophizing and depression partly account for pain from CFS.

Pain increases during exercise [are] probably due to the lack of endogenous analgesia [body's natural pain modulation] and activation of several genes in response to exercise in CFS.

There is currently no evidence in support for the efficacy of complementary medicine in the treatment of pain from CFS.

Intensive education about the biology of pain from CFS (within the framework of central sensitization) has positive short-term effects for patients with CFS, and fatigue-targeting cognitive behavioral therapy appears to be effective for pain from CFS as well.

Limitations:

• The role of the deficient hypothalamus-pituitary-adrenal axis in relation to pain from CFS,

• As well as the interactions with immune (dys)functioning…

…require further study.

Conclusion:

Recent research has increased our understanding of pain from CFS, including its treatment.

It is advocated to optimize current CFS treatment protocols by targeting the underlying mechanism for those patients having severe pain.

Source: Pain Physician, Sep-Oct 2012; 15(5):E677-86. By Nijs J, Crombez G, Meeus M, Knoop H, Van Damme S, Van Cauwenbergh D, Bleijenberg G. Chronic Fatigue Research Group, Vrije Universiteit Brussel, Brussels; Artesis University College Antwerp; University Hospital Brussels; and Ghent University, Belgium; Radboud University Nijmegen Medical Centre, The Netherlands. [Email: Jo.Nijs@vub.ac.be]





Discuss This Article Post a Comment 




[ Be the first to comment on this article ]




 
Free Chronic Fatigue Syndrome and Fibromyalgia Newsletters
Subscribe to
Our FREE
Newsletter
Subscribe Now!
Receive up-to-date ME/CFS & Fibromyalgia treatment and research news
 Privacy Guaranteed  |  View Archives

Save on Your Next Order

Featured Products

FibroSleep™ by ProHealth FibroSleep™ by ProHealth
The All-in-One Natural Sleep Aid
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Optimized Curcumin Longvida® by ProHealth Optimized Curcumin Longvida® by ProHealth
Supports Cognition, Memory & Overall Health
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium

Natural Remedies

IBS, Crohn’s Disease, Colitis, and Other Digestive Disorders IBS, Crohn’s Disease, Colitis, and Other Digestive Disorders
How I Found My Long-Lost Energy How I Found My Long-Lost Energy
Sleep Like a Baby in Nature's Cradle Sleep Like a Baby in Nature's Cradle
Magnesium + Malic Acid: One-Two Punch for Pain & Fatigue Magnesium + Malic Acid: One-Two Punch for Pain & Fatigue
Itching to Find Dry Skin Relief? Itching to Find Dry Skin Relief?

FIBROMYALGIA RESOURCES
What is Fibromyalgia?
Fibromyalgia 101
Fibromyalgia Symptoms
Fibromyalgia Treatments
| CFS RESOURCES
What is CFS?
ME/CFS 101
ME/CFS Symptoms
ME/CFS Treatments
| FORUMS
Fibromyalgia
ME/CFS
ADVANCED MEDICAL LABS
WHOLESALE  |  AFFILIATES
GUARANTEE
CONTACT US
PRIVACY
RSS
SITE MAP
ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus
Credit Card Processing