ProHealth health Vitamin and Natural Supplement Store and Health
Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help

|
|
|
|

Trending News

New Lyme guidelines promote options and informed choice

Phases of clinical depression could affect treatment

“Worm pill” could ease autoimmune disease symptoms

Eating Baked or Broiled Fish Weekly Boosts Brain Health, Pitt Study Says

Preserving Cognitive Function with Aging

Scientists Look for Biomarkers to Improve Treatment of Painful Bladder Condition

New culprit identified in metabolic syndrome

Low vitamin D levels linked to increased risks after noncardiac surgery

9 Health Benefits of Cucumbers

Irritable Bowel Syndrome: Unlocking the Secrets of Peppermint, Acacia and Fennel

 
Print Page
Email Article

Veterans With Gulf War Illness Show Brain Changes Linked to Memory Deficits

  [ 3 votes ]   [ Discuss This Article ]
www.ProHealth.com • October 21, 2013


Veterans With Gulf War Illness Show Brain Changes Linked to Memory Deficits. Image credit: FreeDigitalPhotos.net by renjith krishnan
Image credit: FreeDigitalPhotos.net by renjith krishnan

Editor's Comment: There is a marked similarity in symptoms between ME/CFS and GWI. One of the areas in which symptoms overlap is cognitive impairment. This study examines a cognitive problem commonly experienced by people with ME/CFS - poor working memory. Slow performance in cognitive tasks is one of the most well documented cognitive impairments in ME/CFS. Studies like these, which examine this problem in other related illnesses, serve to shed light on the brain changes common to all of them.

Press Release: Association for Psychological Science, October 15, 2013

New research illuminates definitive brain alterations in troops with Gulf War Illness (GWI) thought to result from the exposure to neurotoxic chemicals, including sarin gas, during the first Persian Gulf War.

“More than 250,000 troops, or approximately 25% of those deployed during the first Persian Gulf War, have been diagnosed with Gulf War Illness (GWI). Although medical professionals have recognized the chronic and often disabling illness for almost two decades, brain changes that uniquely identify GWI have been elusive until now,” explained researcher Bart Rypma, principal investigator at the Center for Brain Health at The University of Texas at Dallas.

This study, published in Clinical Psychological Science, a journal of the Association for Psychological Science, is novel in that it confirms GWI deficits in working memory, a critical cognitive function that enables short-term retention of information for higher-level thinking ability.

In addition, brain alterations revealed in the study show a consistent pattern representing a neurobiological marker that could potentially be used to positively identify GWI.

The research team assessed three aspects of working memory: accuracy, speed, and efficiency. Results showed that participants with GWI performed significantly slower and less accurately than matched healthy veterans, and their efficiency decreased with increasing task difficulty.

During these difficult conditions, the participants showed relatively lower levels of activity in prefrontal brain regions which may compromise their ability to implement effective, higher-level thinking strategies in cognitively demanding situations.

“Our results revealed that at the root of cognitive issues in GWI patients are profound working memory deficits that correlate with a unique brain change visible in the fMRI scanner. These results support an empirical link between exposure to neurotoxic chemicals, specifically sarin nerve gas, and cognitive deficits and neurobiological changes in the brain,” said Rypma. “Implementing interventions that improve working memory could have positive effects on many aspects of daily life from the ability to complete a shopping list, match names with faces, all the way to elevating mood.”

“Difficulty remembering has been the most common, unexplained impairment resulting from service in the 1991 Persian Gulf War,” said Robert Haley, co-investigator and Chief of Epidemiology at UT Southwestern Medical Center in Dallas. “This functional MRI study provides the first objective evidence showing the exact malfunctions in the brain’s memory circuits that underlie these chemically induced memory problems.”

The new findings may also have implications for the treatment of several disorders involving similar neural systems, including Alzheimer’s disease.

“Both GWI and Alzheimer’s disease result in profound cognitive impairment and share similar neurochemical underpinnings,” explained the study’s lead author Nicholas Hubbard. “The distinct neural markers associated with cognitive performance and GWI revealed in our study can be useful for future research to objectively measure the efficacy of treatments for GWI as well as other brain disorders related to the same neurotransmitter system, like Alzheimer’s disease.”


For more information about this study, please contact:

Shelly Kirkland at shelly.kirkland@utdallas.edu,  972-883-3221 (office) or 214-676-1223 (mobile)

The article abstract can be found online HERE.

Additional co-authors include: Joanna L. Hutchison and Michael A. Motes of The University of Texas at Dallas and The University of Texas Southwestern Medical Center; and Ehsan Shokri-Kojori, Ilana J. Bennett, and Ryan M. Brigante of The University of Texas at Dallas.

This work was supported by the Friends of Brain Health research endowment (to N. A. Hubbard), the Department of Veterans Affairs (Grant VA549-P-0027 to R. W. Haley), and the National Institutes of Health (Grant 1R01AG029523 to B. Rypma).

Clinical Psychological Science is APS's newest journal. For a copy of the article "Central Executive Dysfunction and Deferred Prefrontal Processing in Veterans With Gulf War Illness" and access to other Clinical Psychological Science research findings, please contact Anna Mikulak at 202-293-9300 or amikulak@psychologicalscience.org. 



Please Discuss This Article:   Post a Comment 



[ Be the first to comment on this article ]




 
Free Chronic Fatigue Syndrome and Fibromyalgia Newsletters
Subscribe to
Our FREE
Newsletter
Subscribe Now!
Receive up-to-date ME/CFS & Fibromyalgia treatment and research news
 Privacy Guaranteed  |  View Archives

Save on Your Next Order

Featured Products

Optimized Curcumin Longvida® by ProHealth Optimized Curcumin Longvida® by ProHealth
Supports Cognition, Memory & Overall Health
Vitamin D3 Extreme™ by ProHealth Vitamin D3 Extreme™ by ProHealth
50,000 IU Vitamin D3 - Prescription Strength
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function

Natural Remedies

VIDEO: Healthy Eating and Fibromyalgia VIDEO: Healthy Eating and Fibromyalgia
Shoo Pain, Don't Bother Me - Top 10 Nutrients to Take Back Your Life Shoo Pain, Don't Bother Me - Top 10 Nutrients to Take Back Your Life
Running on Empty? Fuel Up with NADH Running on Empty? Fuel Up with NADH
More Weight Loss than Any Other Discovery in Supplement History More Weight Loss than Any Other Discovery in Supplement History
The Remarkable Benefits of Reishi Medicinal Mushrooms The Remarkable Benefits of Reishi Medicinal Mushrooms

FIBROMYALGIA RESOURCES
What is Fibromyalgia?
Fibromyalgia 101
Fibromyalgia Symptoms
Fibromyalgia Treatments
| CFS RESOURCES
What is CFS?
ME/CFS 101
ME/CFS Symptoms
ME/CFS Treatments
| FORUMS
Fibromyalgia
ME/CFS
ADVANCED MEDICAL LABS
WHOLESALE  |  AFFILIATES
GUARANTEE
CONTACT US
PRIVACY
RSS
SITE MAP
ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus
Credit Card Processing