Activate Now
ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Brain White Matter Abnormalities in Female Interstitial Cystitis/Bladder Pain Syndrome: A MAPP Netwo...

How One LLND Treats Lyme disease and Co-infections Using Natural Medicine

Top 7 Nutrient-Dense Foods That Make Calorie Counting Obsolete

Acupuncture reduces hot flashes in breast cancer survivors

For veterans with Gulf War Illness, an explanation for the unexplainable symptoms

SURVEY: Has Your Illness Affected What You Eat?

DePaul Study Recruiting Participants

VIDEO: Dr. Horowitz Discusses Lyme Disease and Chronic Illness

Cocoa flavanols lower blood pressure and increase blood vessel function in healthy people

Detection of Invasive Borrelia burgdorferi Strains in North-Eastern Piedmont, Italy.

Print Page
Email Article

Green tea promotes increased activity in brain's working memory center

  [ 18 votes ]   [ Discuss This Article ] • September 4, 2012

Neural effects of green tea extract on dorsolateral prefrontal cortex
- Source: European Journal of Clinical Nutrition, Aug 29, 2012

By Stefan J Borgwardt, MD, et al.

[Note: According to Wikipedia, "Working memory is the system that holds multiple pieces of transitory information in the mind when needed for verbal and nonverbal tasks such as reasoning and comprehension, and to make them available for further information processing. It is not the same as short term memory [holds passing information, such as a phone number noted, for a very brief time]. Working memory tasks are tasks which require monitoring or manipulation of information or behaviors as part of directed action to a goal." The brain’s dorsolateral prefrontal cortex, where these researchers saw dose-related increases in activity among subjects ingesting green tea extract vs controls, is considered important in working memory processing, and regulation of task-oriented thinking and action.]

Background/Objectives: Green tea is being recognized as a beverage with potential benefits for human health and cognitive functions.

In vivo studies provide preliminary evidence that green tea intake may have a positive role in improving effects on cognitive functions.

We aimed to examine the neural effects of green tea extract on brain activation in humans.

Subjects/Methods: Functional magnetic resonance imaging was recorded while 12 healthy volunteers performed a working memory task following administration of 250 or 500 ml of a milk whey based green tea containing soft drink or milk whey based soft drink without green tea as control in a double-blind, controlled repeated measures within-subject design with counterbalanced order of substance administration.

A whole-brain analysis with a cluster-level threshold of P<0.001 (unadjusted) was followed by an a priori-defined region of interest (ROI) analysis of the dorsolateral prefrontal cortex (DLPFC) including a cluster-level threshold of P<0.05 and family-wise error (FWE) adjustment for multiple comparisons.


• Whole-brain analyses revealed no significant effects after correction for multiple comparisons (FWE P<0.05).

• Using a region of interest (ROI) approach, green tea extract increased activation in the DLPFC relative to a control condition (FWE P<0.001).

• This neural effect was related to green tea dosage.

• Green tea extract was not associated with any significant attenuation [reduced intensity] in regional activation relative to control condition.


• These data suggest that green tea extract may modulate brain activity in the DLPFC, a key area that mediates working memory processing in the human brain.

• Moreover, this is the first neuroimaging study implicating that functional neuroimaging methods provide a means of examining how green tea extract acts on the brain.

Source: European Journal of Clinical Nutrition, Aug 29, 2012. PMID: 22929964, by Borgwardt S, Hammann F, Scheffler K, Kreuter M, Drewe J, Beglinger C. University Hospital Basel, Medical Image Analysis Centre and Department of Psychiatry, University of Basel, Basel, Switzerland; Institute of Psychiatry, King's College London, UK.

Please Discuss This Article:   Post a Comment 

[ Be the first to comment on this article ]

Free Chronic Fatigue Syndrome and Fibromyalgia Newsletters
Subscribe to
Subscribe Now!
Receive up-to-date ME/CFS, Fibromyalgia & Lyme Disease treatment and research news
 Privacy Guaranteed  |  View Archives

Vitamins and Supplements

Featured Products

Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils

Natural Remedies

Everything You Always Wanted to Know About Sleep But Were Too Tired to Ask Everything You Always Wanted to Know About Sleep But Were Too Tired to Ask
Research Links Green Tea to Weight Loss Research Links Green Tea to Weight Loss
Strengthen Cell Function with Energy-Boosting Niagen Strengthen Cell Function with Energy-Boosting Niagen
Front Line Defense Against Colds & Flu - Support for Healthy Immune System Balance Front Line Defense Against Colds & Flu - Support for Healthy Immune System Balance
Dreaming of a Good Night's Sleep? Dreaming of a Good Night's Sleep?

What is Fibromyalgia?
Fibromyalgia Diagnosis
Fibromyalgia Symptoms
Fibromyalgia Causes
Fibromyalgia Treatments
Fibromyalgia Diet
Fibromyalgia Medications
M.E. & CFS
What is M.E./CFS?
M.E./CFS Diagnosis
M.E./CFS Symptoms
M.E./CFS Causes
M.E./CFS Treatments
M.E./CFS Diet
M.E./CFS Medications
What is Lyme Disease?
Lyme Disease Diagnosis
Lyme Disease Symptoms
Lyme Disease Causes
Lyme Disease Treatments
Lyme Disease Diet
Lyme Disease Medications
M.E. & CFS
Lyme Disease
General Health
ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus
Credit Card Processing