ProHealth health Vitamin and Natural Supplement Store and Health
Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help

|
|
|
|

Trending News

CDC Whistleblower Reveals Widespread Manipulation of Scientific Data and Top-Down Pressure on CDC Sc...

Irritable Bowel Syndrome: Unlocking the Secrets of Peppermint, Acacia and Fennel

9 Health Benefits of Cucumbers

How Glutathione Can Save Your Life

Preserving Cognitive Function with Aging

Coenzyme Q10 Benefits Symptoms in Gulf War Veterans: Results of a Randomized Double-Blind Study

Antibiotics in early life may alter immunity long-term

New Research Helps Explain Why Elderly Are Prone to Sleep Problems

Brain inflammation dramatically disrupts memory retrieval networks, UCI study finds

VIDEO: Relaxation - Ocean Voyager Part I

 
Print Page
Email Article

L-theanine by the cup (green tea) or the capsule, no difference found

  [ 3 votes ]   [ Discuss This Article ]
www.ProHealth.com • December 7, 2012


Article:
Kinetics of L-Theanine Uptake and Metabolism in Healthy Participants Are Comparable after Ingestion of L-Theanine via Capsules and Green Tea
-    Source: The Journal of Nutrition, Dec 1, 2012

By Lisa Scheid, Sabine Ellinger, et al.,

[Note: Green tea is a rich source of a family of antioxidants called catechins. One dominant catechin virtually unique to green tea (and mushrooms) is the amino acid called L-theanine. Another well-known catechin unique to green tea is epigallocatechin-3-gallate (EGCG).]

Abstract:
L-Theanine, an amino acid in green tea, is suggested to improve cognition and mood. Therefore, L-theanine is available as a supplement and is now used as an ingredient in functional drinks.

Because data on the metabolic fate of L-theanine from human studies are lacking, we investigated the kinetics of L-theanine uptake and its metabolites [substances produced in the metabolic breakdown of L-theanine], ethylamine and glutamic acid, in healthy participants.

Within a randomized crossover study, 12 participants ingested a bolus of 100 mg L-theanine via capsules or green tea. On further occasions, 3 participants received 50 and 200 mg L-theanine via capsules.

Blood and urine were collected before and up to 24 hours post consumption to determine the concentrations of L-theanine, proteinogenic amino acids, and ethylamine in plasma, erythrocytes, and urine by HPLC.

L-theanine increased in plasma, erythrocytes, and urine with comparable results after both treatments. The maximum plasma concentration of L-theanine occurred 0.8 hours after intake of 100 mg L-theanine via capsules (24.3 +/- 5.7 ?mol/L) and tea (26.5 +/- 5.2 ?mol/L), respectively. The AUC of L-theanine in plasma increased dose dependently after intake of 50, 100, and 200 mg L-theanine via capsules.

Moreover, ethylamine and glutamic acid increased in plasma and were excreted by urine after intake of capsules and tea.

In conclusion, L-theanine is rapidly absorbed and seems to be hydrolyzed [broken down] to ethylamine and glutamic acid.

A minor part of L-theanine is retained in erythrocytes. Kinetics and urinary excretion of L-theanine, ethylamine, and glutamic acid are comparable after both treatments.

Thus, functional effects of L-theanine intake may result from L-theanine, ethylamine, or glutamic acid.

Source: The Journal of Nutrition, Dec 1, 2012. DOI: 10.3945/jn.112.166371, by Scheid L, Ellinger S, Alteheld B, Herholz H, Ellinger J, Henn T, Helfrich HP, Stehle P. Department of Nutrition and Food Science-Nutritional Physiology, and Institute for Numerical Simulation, University of Bonn; Department of Surgery and Department of Urology and Children Urology, University Hospital Bonn; TeeGschwendner, Meckenheim, Germany . [E-mail: ellinger@uni-bonn.de]

 




Please Discuss This Article:   Post a Comment 



[ Be the first to comment on this article ]




 
Free Chronic Fatigue Syndrome and Fibromyalgia Newsletters
Subscribe to
Our FREE
Newsletter
Subscribe Now!
Receive up-to-date ME/CFS & Fibromyalgia treatment and research news
 Privacy Guaranteed  |  View Archives

Save on Vitamin B-12

Featured Products

Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
Vitamin D3 Extreme™ by ProHealth Vitamin D3 Extreme™ by ProHealth
50,000 IU Vitamin D3 - Prescription Strength
Optimized Curcumin Longvida® by ProHealth Optimized Curcumin Longvida® by ProHealth
Supports Cognition, Memory & Overall Health
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
FibroSleep™ by ProHealth FibroSleep™ by ProHealth
The All-in-One Natural Sleep Aid

Natural Remedies

The Brain Boosting and Fatigue Fighting B-12 The Brain Boosting and Fatigue Fighting B-12
Shoo Pain, Don't Bother Me - Top 10 Nutrients to Take Back Your Life Shoo Pain, Don't Bother Me - Top 10 Nutrients to Take Back Your Life
Running on Empty? Fuel Up with NADH Running on Empty? Fuel Up with NADH
Three-Step Strategy to Reverse Mitochondrial Aging Three-Step Strategy to Reverse Mitochondrial Aging
Sleep Like a Baby in Nature's Cradle Sleep Like a Baby in Nature's Cradle

FIBROMYALGIA RESOURCES
What is Fibromyalgia?
Fibromyalgia 101
Fibromyalgia Symptoms
Fibromyalgia Treatments
| CFS RESOURCES
What is CFS?
ME/CFS 101
ME/CFS Symptoms
ME/CFS Treatments
| FORUMS
Fibromyalgia
ME/CFS
ADVANCED MEDICAL LABS
WHOLESALE  |  AFFILIATES
GUARANTEE
CONTACT US
PRIVACY
RSS
SITE MAP
ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus
Credit Card Processing