ProHealth health Vitamin and Natural Supplement Store and Health
Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help

|
|
|
|

Trending News

Gut Bacteria, Artificial Sweeteners and Glucose Intolerance

Culprits of Autism Identified: Toxins, Gut Bacteria, Nutritional Deficiencies, and Vaccines Made wit...

Vitamin E intake critical during 'the first 1,000 days'

Turmeric compound boosts regeneration of brain stem cells

Lower risk of mortality over thirteen year period in association with higher levels of vitamin D

Reverse Mitochondrial Damage

Use of Broad-Spectrum Antibiotics Before Age 2 Associated with Obesity Risk

VIDEO: Beautiful Clouds - Relaxation and Meditation

CoQ10: The Longevity Factor

Elevated plasma biomarkers of chronic inflammation in Gulf War illness

 
Print Page
Email Article

Are Probiotics a Promising Treatment Strategy for Depression?

  [ 12 votes ]   [ Discuss This Article ]
www.ProHealth.com • November 18, 2013


Are Probiotics a Promising Treatment Strategy for Depression?

Press Release: Elsevier through Eurekalert! November 14, 2013

Philadelphia, PA, November 14, 2013 – Probiotics are not new, but their status as a nutritional buzzword is. Most folks have now heard and seen the term countless times in commercials and advertisements, as yogurt, dietary supplement, natural food product, and even cosmetic companies promote their probiotic-containing products.

But what are they, and why are they important? Probiotics are live bacteria that help maintain a healthy digestive system. The development and marketing of products that contain live bacteria has flourished as there is a growing perceived interest in the ingestion of 'natural foods' that might promote health.

Many of the numerous health-improvement claims have yet to be supported scientifically, but these micro-organisms do exert positive effects in intestinal tracts, particularly when used to counteract the effects of antibiotics, which kill both 'bad' and 'good' bacteria. Indeed, the first known description of probiotics occurred in 1908 when a Russian scientist named Élie Metchnikoff observed that rural Europeans who regularly consumed fermented milk product had longer life spans.

Over the past few years, studies have been undertaken to explore the possible impact of probiotics on behavior. It is within this context that the concept of a psychobiotic has arisen.

The authors of a new review article in Biological Psychiatry, Timothy Dinan and his colleagues from University College Cork in Ireland, define a psychobiotic as "a live organism that, when ingested in adequate amounts, produces a health benefit in patients suffering from psychiatric illness."

They review the evidence that these bacteria, when ingested in adequate amounts, offer enormous potential for the treatment of depression and other stress-related disorders.

The gut microbiota, which contains approximately 1 kg of bacteria, can be modulated by diet and many other factors. It is not static and can change from day to day, starting at birth. Evidence has shown that even the form of delivery (vaginal versus cesarean) alters an individual's microbiota.

Early life stress, such as maternal separation, is known to induce long-term changes in the microbiome. Dinan and his colleagues review one study that assessed the potential benefits of a specific probiotic, B. infantis, in rats displaying depressive behavior due to maternal separation. The probiotic treatment normalized both their behavior and their previously-abnormal immune response. This preclinical study and others like it strongly support the hypothesis that probiotics have the potential to exert behavioral and immunological effects.

Some psychobiotics have been shown to have anti-inflammatory effects. This is important because depression and stress are both associated with inflammation in the body. Infectious diseases, such as syphilis and lyme disease, can also produce depressive states. Evidence suggests that immune activations, perhaps via psychobiotic action, could alleviate such states. According to the authors, "the intestinal microbial balance may alter the regulation of inflammatory responses and in so doing, may be involved in the modulation of mood and behavior."

Human studies are still largely lacking, but a few have shown promising results. In one, healthy volunteers received either a probiotic combination (L. helveticus R0052 and B. longum) or placebo for 30 days. Those who received the probiotics reported lower stress levels. In a separate study, volunteers who consumed a yogurt containing probiotics reported improved mood.

"What is clear at this point is that, of the large number of putative probiotics, only a small percentage have an impact on behaviour and may qualify as psychobiotics," said Dinan.

"This intriguing new area of research may open new possibilities for the treatment of depression," said Dr. John Krystal, Editor of Biological Psychiatry.

For now, we must all wait for scientists to conduct large-scale, placebo-controlled trials to provide definitive evidence.


Citation: "Psychobiotics: A Novel Class of Psychotropic" by Timothy G. Dinan, Catherine Stanton, and John F. Cryan (doi: 10.1016/j.biopsych.2013.05.001). The article appears in Biological Psychiatry, Volume 74, Issue 10 (November 15, 2013), published by Elsevier.



Please Discuss This Article:   Post a Comment 



[ Be the first to comment on this article ]




 
Free Chronic Fatigue Syndrome and Fibromyalgia Newsletters
Subscribe to
Our FREE
Newsletter
Subscribe Now!
Receive up-to-date ME/CFS & Fibromyalgia treatment and research news
 Privacy Guaranteed  |  View Archives

Save on Vitamins and Supplements

Featured Products

Optimized Curcumin Longvida® by ProHealth Optimized Curcumin Longvida® by ProHealth
Supports Cognition, Memory & Overall Health
FibroSleep™ by ProHealth FibroSleep™ by ProHealth
The All-in-One Natural Sleep Aid
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
Vitamin D3 Extreme™ by ProHealth Vitamin D3 Extreme™ by ProHealth
50,000 IU Vitamin D3 - Prescription Strength
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils

Natural Remedies

Magnesium + Malic Acid: One-Two Punch for Pain & Fatigue Magnesium + Malic Acid: One-Two Punch for Pain & Fatigue
Are You Obtaining the Proper Enzymes? Are You Obtaining the Proper Enzymes?
"It's Not Easy Being Green" - But It Is Healthy
Itching to Find Dry Skin Relief? Itching to Find Dry Skin Relief?
Live Longer: Groundbreaking Research on Omega-3s Live Longer: Groundbreaking Research on Omega-3s

FIBROMYALGIA RESOURCES
What is Fibromyalgia?
Fibromyalgia 101
Fibromyalgia Symptoms
Fibromyalgia Treatments
| CFS RESOURCES
What is CFS?
ME/CFS 101
ME/CFS Symptoms
ME/CFS Treatments
| FORUMS
Fibromyalgia
ME/CFS
ADVANCED MEDICAL LABS
WHOLESALE  |  AFFILIATES
GUARANTEE
CONTACT US
PRIVACY
RSS
SITE MAP
ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus
Credit Card Processing