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"AT101 Passive Exercise Device" Releases Nitric Oxide and has Beneficial Effects in Inflammatory Diseases

  [ 62 votes ]   [ Discuss This Article ] • November 5, 2003

The AT101 is a comfortable platform, mounted on a hospital-like patient gurney, that moves the body repetitively in a back and forth motion from head to foot, similar to the movement used to comfort a child in a baby carriage but at a more rapid pace, or the passive equivalent of jogging or galloping on a horse.

Two studies presented at the annual meeting of the American College of Chest Physicians by Drs. Sackner and Adams reported that 45 minutes of AT101 application in 14 healthy subjects and 40 patients suffering from a variety of illnesses released nitric oxide in all trials. Nitric oxide is a signaling molecule in the cardiovascular system and levels in the blood are increased naturally in the body during active exercise and accounts for several of its beneficial effects including prevention of arteriosclerosis.

Patients included those with chronic inflammatory diseases including osteoarthritis, Parkinson's disease, multiple sclerosis, neuropathy, FIBROMYALGIA, asthma, CHRONIC FATIGUE SYNDROME, restless legs syndrome, chronic venous insufficiency, and coronary artery disease.

Another paper reported that the magnitude of nitric oxide induced vasodilator effect with AT101 use was similar to low intensity cycling exercise. (They also tested a motorized bicycle that passively moved the legs and did NOT find that this device released nitric oxide.)

Drs. Sackner and Adams said that "nitric oxide is beneficial to the body because it opens blood vessels more widely and suppresses inflammation in a way similar to cortisone products without the harmful side effects of these drugs."

There were statistically significant improvements in vitality, body pain and ability to perform work. "These benefits suggest that the body's release of nitric oxide with the "AT101 passive exercise device" might be beneficial to a large number of other diseases which have as their basis chronic inflammation," added Drs. Sackner and Adams.

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