ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Ultrasound Therapy for Fibromyalgia and Lyme Disease

Curcumin: The All In One Solution, Part 2

What Are the Benefits of Vitamin K2?

Vitamin D deficiency + high fat diet = metabolic syndrome

Why You Should Take Your Apple Cider Vinegar at Night

Use Burdock Oil to Promote Healthy Hair Growth

Meet Your Weight Loss Goals

AMA journal associates iron deficiency with hearing loss

People with forms of early-onset Parkinson's disease may benefit from boosting niacin in diet, resea...

Lutein linked to preservation of crystallized intelligence

 
Print Page
Email Article

Venlafaxine Alleviates Pain and Disability Associated with Fibromyalgia

  [ 550 votes ]   [ Discuss This Article ]
www.ProHealth.com • December 3, 2003


A DGReview of:"Venlafaxine treatment of fibromyalgia"
Annals of Pharmacotherapy

By Mary Beth Nierengarten

Pain and disability associated with fibromyalgia were alleviated in patients who were treated with the antidepressant venlafaxine, reports a study from Turkey.

Despite the unknown pathophysiology of fibromyalgia, the possible role played by central monoaminergic transmission suggests that antidepressants that act on multiple neurotransmitters may improve symptom control.

Kemal Sayar, MD and colleagues from Farabi Hospital, Trabzon, evaluated the efficacy of venlafaxine in 20 patients with fibromyalgia given a fixed-dose of venlafaxine (75 mg/d). Primary outcomes evaluated at 6 and 12 weeks of the study were clinical severity of disease (measured by Fibromyalgia Impact Questionnaire (FIQ)) and degree of pain (measured by the Visual Analog Scale (VAS)). Other scales used to measure an association between psychological distress and physical symptoms included the Beck Depression and Anxiety Inventories and the Hamilton Depression and Anxiety scales.

Of the 20 patients enrolled in the study, 5 discontinued treatment after 1 week of treatment because of treatment-related adverse effects. Of the remaining 15 patients, the mean duration of disease was 3.7 years, the mean age was 37.7 years, 14 were married, 9 did not have any current psychiatric disorder (3 of whom had a history of major depressive disorder), 5 had generalized anxiety disorder, and 1 had bipolar disorder.

No significant decrease in pain was noted at 6 weeks after treatment initiation, but a significant improvement in pain intensity (P = .0001) and disability caused by fibromyalgia (P = .0001) were found at 12 weeks. A significant decrease in anxiety and depression was also found at 12 weeks compared to baseline. Having a current or past psychiatric disorder was not associated with any difference in perceived pain scores, with no significant associations found between FIQ scores and anxiety and depression measures.

Several limitations of this study include its study design (i.e., open trial), lack of measurement of tender points, withdrawal of 5 patients due to treatment-associated adverse effects, and small sample size.

With these caveats, the authors conclude that venlafaxine is a promising treatment for alleviating symptoms of pain and disability associated with fibromyalgia that should be further evaluated in placebo-controlled, double-blinded studies.

Ann Pharmacother 2003;37:11:1561-5. "Venlafaxine treatment of fibromyalgia"

Source: www.docguide.com. Copyright (c) 1995-2003 Doctor's Guide Publishing Limited.



Post a Comment

Featured Products From the ProHealth Store
Ultra ATP+, Double Strength Mitochondria Ignite™ with NT Factor® Vitamin D3 Extreme™

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products


Article Comments



Be the first to comment on this article!

Post a Comment


 
NAD+ Ignite with Niagen

Featured Products

Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils

Natural Remedies

Restoring Gut Health: How to Create a Firewall Against Toxins Entering the Gut Wall Restoring Gut Health: How to Create a Firewall Against Toxins Entering the Gut Wall
Coconut Oil - Healthy Gifts from the 'Tree of Life' Coconut Oil - Healthy Gifts from the 'Tree of Life'
Looking for Energy? Turn to Plants. Looking for Energy? Turn to Plants.
Restore Youthful Cognition and Well-Being Restore Youthful Cognition and Well-Being
Pioneer Scientists Uncover a Revolutionary Neuroprotective Supplement for Nerve Health Pioneer Scientists Uncover a Revolutionary Neuroprotective Supplement for Nerve Health

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map