ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

SURVEY: Weight Management & Chronic Illness

Japanese green tea consumers have reduced risk of dementia

Do Nothing, Accomplish Everything! The Connection Between Breathing and Healing

Meet the ProHealth Editors

Best Herbs to Help With Insomnia

Choline: Why You Should Eat Your Egg Yolks and Take Krill

Calcium, vitamin D supplementation associated improved stroke recovery

Acupressure reduced fatigue in breast cancer survivors

More positive evidence for melatonin in breast cancer battle

Omega-3 shows promise as stroke treatment

 
Print Page
Email Article

Increased Free Radical Levels May Cause Fibromyalgia

  [ 751 votes ]   [ Discuss This Article ]
www.ProHealth.com • January 19, 2004


A DGReview of: "Free radicals and antioxidants in primary fibromyalgia: an oxidative stress disorder?"

Rheumatology International

01/07/2004

By Mary Beth Nierengarten

Fibromyalgia may be an oxidative disorder as indicated by the increased levels of malondialdehyde (MDA) and decreased levels of superoxide dismutase (SOD) in patients with this disease, reports a study from Turkey.

Although the aetiology of fibromyalgia remains unknown, recent data suggest that the oxidant/antioxidant balance may play a role in its development.

Based on the hypothesis that a balance discordance in the oxidant/antioxidant status may indicate that fibromyalgia is an oxidative disorder, Selda Bagis, MD, Mersin University Medical School, and colleagues compared the oxidant/antioxidant status of 85 women with primary fibromyalgia to that of 80 healthy, age-, weight-, and height-matched women. Along with evaluation of sex hormone profiles and routine blood, sedimentation, thyroid, C-reactive, liver, and kidney function tests, body mass index (BMI), smoking, and duration of disease were also documented for all patients. Pain was evaluated using the visual analog scale (VAS) and the presence and number of tender points were recorded. Assessment of the oxidant/antioxidant status was based on measuring MDA, which is a marker of free radical damage, and SOD, which shows antioxidant capacity.

In patients with fibromyalgia, MDA levels were significantly higher (P = .000) and SOD levels significantly lower (P = .000) than in the control patients. Number of tender points and VAS were not significantly associated with MDA or SOD (P > .05), and no correlation was found between BMI, age, duration of disease and MDA or SOD (P > .05).

These data suggest, claim the authors, that the "oxidant/antioxidant imbalance related to the disease process, and the increase in free radical levels may be responsible for the development of fibromyalgia."

The authors conclude that these data support their hypothesis that fibromyalgia is an oxidative disorder, and that additional larger studies are needed for validation.

Rheumatol Int 2003 Dec 20;[Epub ahead of print]. "Free radicals and antioxidants in primary fibromyalgia: an oxidative stress disorder?"

Source: Doctor’s Guide (DG) online. (C) Doctor's Guide, online at www.docguide.com.



Post a Comment

Featured Products From the ProHealth Store
Ultra EPA  - Fish Oil Vitamin D3 Extreme™ Energy NADH™ 12.5mg

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products


Article Comments



Be the first to comment on this article!

Post a Comment


 
Natural Pain Relief Supplements

Featured Products

FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health

Natural Remedies

Probiotic Mint Promotes Healthy Gums & Teeth, Freshens Breath and Whitens Teeth Probiotic Mint Promotes Healthy Gums & Teeth, Freshens Breath and Whitens Teeth
Herbal Rescue for High Blood Sugar Herbal Rescue for High Blood Sugar
The Curcumin Revolution: 'Golden' Ticket to Better Health The Curcumin Revolution: 'Golden' Ticket to Better Health
Can Glycine + Amino Acids Be the Secret to Deep, Rejuvenating Sleep? Can Glycine + Amino Acids Be the Secret to Deep, Rejuvenating Sleep?
Breaking Through the Mental Fog Breaking Through the Mental Fog

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE AND SAVE 15% NOW*
Be the first to know about new products, special discounts and the latest health news. *New subscribers only

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2016 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map