ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Relief for IBS, Colitis, Crohn’s And More

B Vitamins May Protect Against Damaging Effects of Air Pollution, and Improve Cognition and Psychiat...

Restless Leg Syndrome (RLS) - are you running a marathon each night?

Can Magnesium Relieve Your Tinnitus?

Resveratrol Proven to Slow Brain Aging

Magnesium Protects Against Stroke, Heart Disease and Diabetes

Fruits and vegetables' latest superpower? Lowering blood pressure

Neroli Oil: The Pleasantly Fragrant Citrus Oil

Prenatal vitamin D could help prevent autism in children

Restoring NAD+ could reduce DNA damage accumulation

 
Print Page
Email Article

Increased Free Radical Levels May Cause Fibromyalgia

  [ 751 votes ]   [ Discuss This Article ]
www.ProHealth.com • January 19, 2004


A DGReview of: "Free radicals and antioxidants in primary fibromyalgia: an oxidative stress disorder?"

Rheumatology International

01/07/2004

By Mary Beth Nierengarten

Fibromyalgia may be an oxidative disorder as indicated by the increased levels of malondialdehyde (MDA) and decreased levels of superoxide dismutase (SOD) in patients with this disease, reports a study from Turkey.

Although the aetiology of fibromyalgia remains unknown, recent data suggest that the oxidant/antioxidant balance may play a role in its development.

Based on the hypothesis that a balance discordance in the oxidant/antioxidant status may indicate that fibromyalgia is an oxidative disorder, Selda Bagis, MD, Mersin University Medical School, and colleagues compared the oxidant/antioxidant status of 85 women with primary fibromyalgia to that of 80 healthy, age-, weight-, and height-matched women. Along with evaluation of sex hormone profiles and routine blood, sedimentation, thyroid, C-reactive, liver, and kidney function tests, body mass index (BMI), smoking, and duration of disease were also documented for all patients. Pain was evaluated using the visual analog scale (VAS) and the presence and number of tender points were recorded. Assessment of the oxidant/antioxidant status was based on measuring MDA, which is a marker of free radical damage, and SOD, which shows antioxidant capacity.

In patients with fibromyalgia, MDA levels were significantly higher (P = .000) and SOD levels significantly lower (P = .000) than in the control patients. Number of tender points and VAS were not significantly associated with MDA or SOD (P > .05), and no correlation was found between BMI, age, duration of disease and MDA or SOD (P > .05).

These data suggest, claim the authors, that the "oxidant/antioxidant imbalance related to the disease process, and the increase in free radical levels may be responsible for the development of fibromyalgia."

The authors conclude that these data support their hypothesis that fibromyalgia is an oxidative disorder, and that additional larger studies are needed for validation.

Rheumatol Int 2003 Dec 20;[Epub ahead of print]. "Free radicals and antioxidants in primary fibromyalgia: an oxidative stress disorder?"

Source: Doctor’s Guide (DG) online. (C) Doctor's Guide, online at www.docguide.com.



Post a Comment

Featured Products From the ProHealth Store
Optimized Curcumin Longvida® Ultra EPA  - Fish Oil Vitamin D3 Extreme™

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products


Article Comments



Be the first to comment on this article!

Post a Comment


 
NAD+ Ignite with Niagen

Featured Products

FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength

Natural Remedies

"It's Not Easy Being Green" - But It Is Healthy
Breakthrough Form of Magnesium Enhances Memory and Cognitive Function Breakthrough Form of Magnesium Enhances Memory and Cognitive Function
How to Jump-start and Sustain Energy Production in CFS How to Jump-start and Sustain Energy Production in CFS
Probiotic Mint Promotes Healthy Gums & Teeth, Freshens Breath and Whitens Teeth Probiotic Mint Promotes Healthy Gums & Teeth, Freshens Breath and Whitens Teeth
Thyroid Health and Fibromyalgia Thyroid Health and Fibromyalgia

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map