ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Astaxanthin Is a Longevity Promoter

Meta-analysis links vitamin D deficiency with increased risk of mortality during 10.5 year median pe...

Prevent Or Reverse Diabetes: An Amazing Herbal Intervention

Exercise and Vitamin D Better Together for Heart Health

VIDEO: Essential Oils for Weight Loss

Can Valerian Root Help You Sleep Better?

Eight servings of veggies a day is clearly best for the heart

Can Ginkgo Give Your Brain a Boost?

Fighting Statin-Induced Diabetes with CoQ10

The Many Wonders of Calming Sandalwood Oil

 
Print Page
Email Article

Antidepressant Cymbalta Helps Relieve Fibromyalgia Symptoms?

  [ 961 votes ]   [ 4 Comments ]
www.ProHealth.com • October 20, 2004


By Elizabeth Querna

Fibromyalgia affects between 3 and 6 percent of the population, mainly women, causing chronic pain all over the body as well as headaches, fatigue, and other complications. It is still not well understood, though studies have linked the disease to abnormal amounts of the chemicals serotonin and norepinephrine, which are also associated with depression. Some researchers from the University of Cincinnati and other places wondered if drugs that are used for depression could also help fibromyalgia patients.

What the researchers wanted to know: Does Cymbalta, an antidepressant with the generic name duloxetine, help patients with fibromyalgia? What they did: The researchers recruited about 200 patients from around the country and split them into two equal groups. One group received Cymbalta for 12 weeks, and the other group received a placebo for the same amount of time. Participants completed several questionnaires to measure the amount of pain and discomfort the disease caused them at the beginning of the study, and then at the end of each of the first two weeks and every second week for the remaining 12 weeks of the study. Researchers also tested the participants for depression.

What they found: Women who took Cymbalta had significantly less pain and discomfort than those who took the placebo. For men, who made up only 11 percent of the study, there was no effect from taking the medication compared with a placebo. Depression played no part in whether or not the drug worked to control pain. The change in the level of women's pain was particularly pronounced after a month of taking the drug, then leveled off a bit before dropping again near the end of the study.

What it means to you: Cymbalta could be a good therapy for people suffering from fibromyalgia. Because the disease is not well understood, no one knows the best way to treat it or why certain drugs work and others don't. Other antidepressants, including Prozac, Elavil, and Endep, have also been shown to reduce symptoms of the disease, so those types of drugs may become a standard treatment.

Caveats: In most tests, Cymbalta improved the score of participants. However, in one of the primary measures of pain there was no significant difference between the two groups at the end of the 12-week trial. Also, because the trial lasted only 12 weeks, it is impossible to tell how well the drug would control treatment for a longer period of time. Lastly, the primary researcher on the project has received more than $10,000 in consulting fees from Eli Lilly, the manufacturer of Cymbalta, and other researchers also have ties to the company.

Reference: Arnold, L.M. et al. "A Double-Blind, Multicenter Trial Comparing Duloxetine With Placebo in the Treatment of Fibromyalgia Patients With or Without Major Depressive Disorder." Arthritis and Rheumatism. September 2004, Vol. 50, No. 9, pp. 2974–2984. Source: U.S. News & World Report



Post a Comment

Featured Products From the ProHealth Store
Vitamin D3 Extreme™ FibroSleep™ Mitochondria Ignite™ with NT Factor®

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products


Article Comments Post a Comment

it helped me
Posted by: jbarnett
Oct 17, 2007
I take cymbalta on a daily basis, when I was first given the prescription I thought ok, my doctor must think I am a lunatic and thought I must just be depressed, but it really helps me with the manageablility of pain....I told him I wasnt depressed, and he agreed, he said depression is not only a mental status, but a physical one as well, and that my body was depressed (physically). I thought ok kinda makes sense....he was right. I went from 1800mg (plus) daily of Ibuprophen, to just one 60mg pill of cymbalta...will it work forever, who knows. I am just glad to be pain free 90% of the time.
Reply Reply

 
Cymbalta and FM
Posted by: calhawaiigirl
Apr 7, 2008
I have had FM for at least 20 years. They had a different name for it in the beginning. I can't remember what they gave me at first but in the 90s I took Elavil a lot. It helped me but I hated that hangover affect it gave me. Half the day was gone by the time the drug wore off. I started taking a lot of Acetamenophen and Ibuprophen and ended up with reflux disease. I took Celebrex for years but it didn't really help me. I started taking Cymbalta around January of last year. My pain is at least half of what it was. I can actually function somewhat. However, I am still struggling with chronic fatigue.

 

 
NAD+ Ignite with Niagen

Featured Products

Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength

Natural Remedies

How to Jump-start and Sustain Energy Production in CFS How to Jump-start and Sustain Energy Production in CFS
Enhance Eyelashes Naturally Enhance Eyelashes Naturally
Can Autoimmune Conditions be Reversed? Researchers Make a Surprising Discovery Can Autoimmune Conditions be Reversed? Researchers Make a Surprising Discovery
The Big Blue Fish that Helps Chase the Blues Away The Big Blue Fish that Helps Chase the Blues Away
Improve Cardiovascular and Metabolic Health with Omega-7 Improve Cardiovascular and Metabolic Health with Omega-7

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map