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Blood Test Shows Distinct Promise as Tool for Diagnosing CFS

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By Editor • • July 10, 2006

Recent tests using spectroscopic blood serum analysis successfully sorted the blood of healthy subjects from that of diagnosed Chronic Fatigue Syndrome patients with a 97 percent accuracy rate, according to a study by virologists at Japan’s Osaka University and Osaka City University School of Medicine. First, the researchers analyzed the serum of 77 known CFS patients and 71 healthy subjects using a visible and near-infrared (Vis-NIR) spectroscopy analysis. (Spectroscopy arrays molecular energy frequencies along a spectrum to depict the composition of complex substances.) They found that the CFS blood samples and the healthy samples seemed to produce two different profiles, or models. Next, they ran a test to see if they could use these models to sort out CFS serum samples from healthy samples. Working with a masked group of 99 subjects, they found that the spectroscopy analysis correctly classified the blood samples for all 54 of the 54 healthy subjects, and for 42 of the 45 CFS patients. The study report, “Spectroscopic diagnosis of Chronic Fatigue Syndrome by visible and near-infrared spectroscopy in serum samples,” by Akikazu Sakudo, et al., was published in the July 14, 2006 issue of Biochemical and Biophysical Research Communications. An abstract of the article is available at

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