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Fibromyalgia, infection and vaccination: Two more parts in the etiological puzzle

  [ 232 votes ]   [ 3 Comments ]
By JN Ablin, et al • www.ProHealth.com • November 8, 2006


Journal: Journal of Autoimmunity, 2006 Oct 30 [E-publication ahead of print October 30, 2006] Authors and affiliation: Ablin JN, Shoenfeld Y, Buskila D. Department of Rheumatology, Tel-Aviv Sourasky Medical Center and Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel. [E-mail: ajacob@post.tau.ac.il ] PMID: 17071055 DOI: 10.1016/j.jaut.2006.09.004

As the pathogenesis of Fibromyalgia continues to raise debate, multiple putative triggers have been implicated. The current review summarizes the available data linking Fibromyalgia to either infection or vaccination. Multiple infectious agents have been associated with the development of either full-blown Fibromyalgia (for example Hepatitis C), or with symptom complexes extensively overlapping with that syndrome (for example chronic Lyme disease). The cases of Lyme disease, mycoplasma, hepatitis C and HIV are detailed. Despite the described associations, no evidence is available demonstrating the utility of antibiotic or anti-viral treatment in the management of Fibromyalgia. Possible mechanistic links between Fibromyalgia and HIV are reviewed.

Associations have been described between various vaccinations and symptom complexes including Fibromyalgia and Chronic Fatigue Syndrome. The case of Gulf War syndrome, a functional multisystem entity sharing many clinical characteristics with Fibromyalgia is discussed, with emphasis on the possibility of association with administration of multiple vaccinations during deployment in the Persian Gulf and the interaction with stress and trauma. Based on this example a model is proposed, wherein vaccinations function as co-triggers for the development of functional disorders including Fibromyalgia, in conjunction with additional contributing factors.

Keywords: Fibromyalgia; Infection; Vaccination




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Article Comments Post a Comment

FM and flu vaccine
Posted by: harwoodjill9
Nov 9, 2006
On Friday, November3,2006 I received this year's flu shot in my left arm. The next day, I had so much pain, that I was in tears and had to go home to spend the day in bed. I saw my physical therapist, who said I have tendonitis in my right shoulder. The subject of the flu shot did not come up. It didn't occur to me. I had a hemi-shoulder joint replacement in my right shoulder 8/16/05. I thought I had re-injured it, swimming. Could there be a connection to my pain--which radiated down my right arm and the right side of my back--and the flu shot. I was diagnosed with FM in 2003.harwoodjill9
Reply Reply

 
pain after flu shot
Posted by: usyankee
Mar 4, 2009
After I had gotten stuck with a needle at work, I was given a tetanus shot despite my arguing the fact that the needle wasn't rusty (!) and I had one in less than 10 years. The walk-in stated it is now recommended that one has one every 5 years.

After I got the shot, I had terrible pain and spasms at the injection site. Over the course of 2 months the pain and spasms spread and my whole body was having spasms, keeping me awake at night. After the two months came boiling burning pain with more frequent spasms. Sometimes I would wake up in the middle of the night only to find my raised arm come down and slap me in the face. The boiling burning pain was so horrible, I would go in the bathroom at work and cry, compose myself, and repeat it during work many times. Sometimes it would feel like raw pain-painful when touching lightly, other times it would feel like I was compressed in a glovebox all night then my inner skin pulled tautly. It would not go away. If I used my muscles too much I would lose the strength in them. I couldn't raise my arms over my head or raise my arm to keep it on the steering wheel for long to drive a car without severe pain. I was weak if I didn't rest my muscles and body. I would get the burning boiling pain when I didn't sleep enough. Loud sounds began to bother me.

I went to MD after MD until I was finally diagnosed with fibromyalgia. When I told doctors it happened after a tetanus shot, no one looked into it or I think believed me. That was 10 years ago.

 


fibromyalgia and tetanus shot
Posted by: usyankee
Mar 4, 2009
After I had gotten stuck with a needle at work, I was given a tetanus shot despite my arguing the fact that the needle wasn't rusty (!) and I had one in less than 10 years. The walk-in stated it is now recommended that one has one every 5 years. After I got the shot, I had terrible pain and spasms at the injection site. Over the course of 2 months the pain and spasms spread and my whole body was having spasms, keeping me awake at night. After the two months came boiling burning pain with more frequent spasms. Sometimes I would wake up in the middle of the night only to find my raised arm come down and slap me in the face. The boiling burning pain was so horrible, I would go in the bathroom at work and cry, compose myself, and repeat it during work many times. Sometimes it would feel like raw pain-painful when touching lightly, other times it would feel like I was compressed in a glovebox all night then my inner skin pulled tautly. It would not go away. If I used my muscles too much I would lose the strength in them. I couldn't raise my arms over my head or raise my arm to keep it on the steering wheel for long to drive a car without severe pain. I was weak if I didn't rest my muscles and body. I would get the burning boiling pain when I didn't sleep enough. Loud sounds began to bother me. I went to MD after MD until I was finally diagnosed with fibromyalgia. When I told doctors it happened after a tetanus shot, no one looked into it or I think believed me. That was 10 years ago.
Reply Reply
 
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