ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

American Heart Association Renders Itself Obsolete With 1960s Dietary Advice on Coconut Oil

Is Coconut Oil Healthy? (The American Heart Association Doesn’t Think So)

Inflammation Disrupts Memory - What Can You Do to Protect Your Brain?

Health Benefits of Artichokes

Putting the Spotlight on Coriander Seed Oil

Are Americans Really Getting Too Much Vitamin D? A Critical Look at Recent Media Warnings

Migraines? Powdered Ginger May Help

Eating more vegetable protein may protect against early menopause

Is Activated Charcoal Beneficial?

German Chamomile Oil: A Versatile Essential Oil You Should Have at Home

 
Print Page
Email Article

Active Human Herpesvirus six (HHV-6) infections in patients with Chronic Fatigue Syndrome (CFS) and relapsing-remitting multiple sclerosis (RRMS)

  [ 218 votes ]   [ Discuss This Article ]
By KK. Knox and DR Carrigan • www.ProHealth.com • January 17, 2007


Journal: Journal of Clinical Virology, Vol. 37, Supplement I, December 2006, pg. S116. [Supplement sponsored by HHV-6 Foundation. E-Publication Jan 10. 2007. Full text is available for a fee at http://www.sciencedirect.com/science/journal/13866532 ] Authors and affiliation: K.K. Knox, D.R. Carrigan. Institute for Viral Pathogenesis, Milwaukee, Wisconsin, USA. [E-mail: kknox@ivpresearch.org ]

Background: Data from a number of laboratories have implicated HHV-6 as being involved in the pathogenesis of CFS and MS.

Objectives: The study described here focuses on the use of various diagnostic technologies to compare the incidence of active HHV-6 infections in MS patients, patients with CFS and healthy control subjects.

Study Design: Blood samples were obtained from four groups: 1. A cross-section of CFS patients, 2. Patients with relapsing-remitting MS at the time of clinical relapse, 3. The same MS patients after the relapse had resolved, and 4. Healthy control subjects. Blood leukocytes were assessed for active HHV-6 infection by a rapid culture assay and by an HHV-6 specific antigenemia assay. Plasma samples were analyzed by a nested HHV-6 PCR technique.

Results: See the Table Healthy Controls
n Rapid HHV-6 culture: 2% (1/55)
n HHV-6 antigenemia: 7% (4/55)
n Nested Plasma PCR: 0% (0/68) CFS Patients
n Rapid HHV-6 culture: 25% (20/81) p<0.0002 (comparison to healthy controls by Fisher’s Two-sided Exact Test)
n HHV-6 antigenemia: 31%(25/81) p<0.001
n Nested Plasma PCR: 22% (11/49) p<0.0001 MS at relapse
n Rapid HHV-6 culture: 48% (15/31) p<0.0001
n HHV-6 antigenemia: 45% (14/31) p<0.0001
n Nested Plasma PCR: 24% (6/25) p<0.0002
MS after relapse
n Rapid HHV-6 culture: 19% (6/31) p<0.008
n HHV-6 antigenemia: 10% (3/31) Not significant
n Nested Plasma PCR: 11% (3/28) p<0.03

Conclusions: There exists a subpopulation of CFS patients who have chronic, active infections with HHV-6. This subset of CFS patients is remarkably similar to patients with relapsing-remitting MS with respect to their active HHV-6 infections. Diagnosis of such HHV-6 infections is most effectively achieved by the use of two complementary procedures, i.e. nested PCR with plasma or serum samples and rapid culture/antigenemia using patient blood leukocytes.




Post a Comment

Featured Products From the ProHealth Store
Energy NADH™ 12.5mg Ultra ATP+, Double Strength Mitochondria Ignite™ with NT Factor®

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products


Article Comments



Be the first to comment on this article!

Post a Comment


 
NAD+ Ignite with Niagen

Featured Products

Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength

Natural Remedies

Natural Bladder Control, Go Less and Live More Natural Bladder Control, Go Less and Live More
The Crucial Role CoQ10 Plays in Fibromyalgia and ME/CFS The Crucial Role CoQ10 Plays in Fibromyalgia and ME/CFS
Mitochondria-Booster NIAGEN® Shows Promise in First Human Clinical Trial Mitochondria-Booster NIAGEN® Shows Promise in First Human Clinical Trial
When a Negative is Positive - Goodnighties Recovery Sleepwear When a Negative is Positive - Goodnighties Recovery Sleepwear
Can Glycine + Amino Acids Be the Secret to Deep, Rejuvenating Sleep? Can Glycine + Amino Acids Be the Secret to Deep, Rejuvenating Sleep?

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map