Activate Now
 
ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Patient Insights into the Design of Technology to Support a Strengths-Based Approach to Health Care.

SURVEY: Weight Management & Chronic Illness

Japanese green tea consumers have reduced risk of dementia

Do Nothing, Accomplish Everything! The Connection Between Breathing and Healing

Meet the ProHealth Editors

Best Herbs to Help With Insomnia

Choline: Why You Should Eat Your Egg Yolks and Take Krill

Calcium, vitamin D supplementation associated improved stroke recovery

Acupressure reduced fatigue in breast cancer survivors

More positive evidence for melatonin in breast cancer battle

 
Print Page
Email Article

Active Human Herpesvirus six (HHV-6) infections in patients with Chronic Fatigue Syndrome (CFS) and relapsing-remitting multiple sclerosis (RRMS)

  [ 218 votes ]   [ Discuss This Article ]
By KK. Knox and DR Carrigan • www.ProHealth.com • January 17, 2007


Journal: Journal of Clinical Virology, Vol. 37, Supplement I, December 2006, pg. S116. [Supplement sponsored by HHV-6 Foundation. E-Publication Jan 10. 2007. Full text is available for a fee at http://www.sciencedirect.com/science/journal/13866532 ] Authors and affiliation: K.K. Knox, D.R. Carrigan. Institute for Viral Pathogenesis, Milwaukee, Wisconsin, USA. [E-mail: kknox@ivpresearch.org ]

Background: Data from a number of laboratories have implicated HHV-6 as being involved in the pathogenesis of CFS and MS.

Objectives: The study described here focuses on the use of various diagnostic technologies to compare the incidence of active HHV-6 infections in MS patients, patients with CFS and healthy control subjects.

Study Design: Blood samples were obtained from four groups: 1. A cross-section of CFS patients, 2. Patients with relapsing-remitting MS at the time of clinical relapse, 3. The same MS patients after the relapse had resolved, and 4. Healthy control subjects. Blood leukocytes were assessed for active HHV-6 infection by a rapid culture assay and by an HHV-6 specific antigenemia assay. Plasma samples were analyzed by a nested HHV-6 PCR technique.

Results: See the Table Healthy Controls
n Rapid HHV-6 culture: 2% (1/55)
n HHV-6 antigenemia: 7% (4/55)
n Nested Plasma PCR: 0% (0/68) CFS Patients
n Rapid HHV-6 culture: 25% (20/81) p<0.0002 (comparison to healthy controls by Fisher’s Two-sided Exact Test)
n HHV-6 antigenemia: 31%(25/81) p<0.001
n Nested Plasma PCR: 22% (11/49) p<0.0001 MS at relapse
n Rapid HHV-6 culture: 48% (15/31) p<0.0001
n HHV-6 antigenemia: 45% (14/31) p<0.0001
n Nested Plasma PCR: 24% (6/25) p<0.0002
MS after relapse
n Rapid HHV-6 culture: 19% (6/31) p<0.008
n HHV-6 antigenemia: 10% (3/31) Not significant
n Nested Plasma PCR: 11% (3/28) p<0.03

Conclusions: There exists a subpopulation of CFS patients who have chronic, active infections with HHV-6. This subset of CFS patients is remarkably similar to patients with relapsing-remitting MS with respect to their active HHV-6 infections. Diagnosis of such HHV-6 infections is most effectively achieved by the use of two complementary procedures, i.e. nested PCR with plasma or serum samples and rapid culture/antigenemia using patient blood leukocytes.




Post a Comment

Featured Products From the ProHealth Store
Ultra EPA  - Fish Oil Ultra ATP+, Double Strength Mitochondria Ignite™ with NT Factor®

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products


Article Comments



Be the first to comment on this article!

Post a Comment


 
Natural Pain Relief Supplements

Featured Products

Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils

Natural Remedies

The Most Powerful Natural Antioxidant Discovered to Date - Hydroxytyrosol The Most Powerful Natural Antioxidant Discovered to Date - Hydroxytyrosol
Magnesium: An Essential Supplement for ME/CFS Magnesium: An Essential Supplement for ME/CFS
Reversing Neurodegeneration with a New Magnesium Compound Reversing Neurodegeneration with a New Magnesium Compound
Health Benefits Are Brewing in Green Tea Health Benefits Are Brewing in Green Tea
When a Good Night's Sleep Is Just a Daydream... When a Good Night's Sleep Is Just a Daydream...

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE AND SAVE 15% NOW*
Be the first to know about new products, special discounts and the latest health news. *New subscribers only

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2016 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map