ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Can Autoimmune Conditions be Reversed? Researchers Make a Surprising Discovery

Scientifically-designed fasting diet lowers risks for major diseases

How One Tiny Molecule Turned into One Huge Health Breakthrough

Acupuncture boosts effectiveness of standard medical care for chronic pain, depression

Research on Astaxanthin Demonstrates Significant Whole Body Benefits

Humans have three times more brown body fat

Nutrients Boost Stem Cell Function

B12 Proven Essential for Every Cell

Soy isoflavones may benefit breast cancer patients

Dietary prebiotics improve sleep, buffer impacts of stress, says study

 
Print Page
Email Article

Active Human Herpesvirus six (HHV-6) infections in patients with Chronic Fatigue Syndrome (CFS) and relapsing-remitting multiple sclerosis (RRMS)

  [ 218 votes ]   [ Discuss This Article ]
By KK. Knox and DR Carrigan • www.ProHealth.com • January 17, 2007


Journal: Journal of Clinical Virology, Vol. 37, Supplement I, December 2006, pg. S116. [Supplement sponsored by HHV-6 Foundation. E-Publication Jan 10. 2007. Full text is available for a fee at http://www.sciencedirect.com/science/journal/13866532 ] Authors and affiliation: K.K. Knox, D.R. Carrigan. Institute for Viral Pathogenesis, Milwaukee, Wisconsin, USA. [E-mail: kknox@ivpresearch.org ]

Background: Data from a number of laboratories have implicated HHV-6 as being involved in the pathogenesis of CFS and MS.

Objectives: The study described here focuses on the use of various diagnostic technologies to compare the incidence of active HHV-6 infections in MS patients, patients with CFS and healthy control subjects.

Study Design: Blood samples were obtained from four groups: 1. A cross-section of CFS patients, 2. Patients with relapsing-remitting MS at the time of clinical relapse, 3. The same MS patients after the relapse had resolved, and 4. Healthy control subjects. Blood leukocytes were assessed for active HHV-6 infection by a rapid culture assay and by an HHV-6 specific antigenemia assay. Plasma samples were analyzed by a nested HHV-6 PCR technique.

Results: See the Table Healthy Controls
n Rapid HHV-6 culture: 2% (1/55)
n HHV-6 antigenemia: 7% (4/55)
n Nested Plasma PCR: 0% (0/68) CFS Patients
n Rapid HHV-6 culture: 25% (20/81) p<0.0002 (comparison to healthy controls by Fisher’s Two-sided Exact Test)
n HHV-6 antigenemia: 31%(25/81) p<0.001
n Nested Plasma PCR: 22% (11/49) p<0.0001 MS at relapse
n Rapid HHV-6 culture: 48% (15/31) p<0.0001
n HHV-6 antigenemia: 45% (14/31) p<0.0001
n Nested Plasma PCR: 24% (6/25) p<0.0002
MS after relapse
n Rapid HHV-6 culture: 19% (6/31) p<0.008
n HHV-6 antigenemia: 10% (3/31) Not significant
n Nested Plasma PCR: 11% (3/28) p<0.03

Conclusions: There exists a subpopulation of CFS patients who have chronic, active infections with HHV-6. This subset of CFS patients is remarkably similar to patients with relapsing-remitting MS with respect to their active HHV-6 infections. Diagnosis of such HHV-6 infections is most effectively achieved by the use of two complementary procedures, i.e. nested PCR with plasma or serum samples and rapid culture/antigenemia using patient blood leukocytes.




Post a Comment

Featured Products From the ProHealth Store
Ultra ATP+, Double Strength Mitochondria Ignite™ with NT Factor® FibroSleep™

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products


Article Comments



Be the first to comment on this article!

Post a Comment


 
NAD+ Ignite with Niagen

Featured Products

Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid

Natural Remedies

Undenatured Type II Collagen - Chicken Soup for Your Joints Undenatured Type II Collagen - Chicken Soup for Your Joints
Herbal Rescue for High Blood Sugar Herbal Rescue for High Blood Sugar
The Surprising Benefits of Probiotics - What You Didn't Know The Surprising Benefits of Probiotics - What You Didn't Know
IBS, Crohn’s Disease, Colitis, and Other Digestive Disorders IBS, Crohn’s Disease, Colitis, and Other Digestive Disorders
Strengthen Cell Function with Energy-Boosting Niagen Strengthen Cell Function with Energy-Boosting Niagen

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map