ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

15 Health Benefits of Chia Seeds, According to Science

Tangerine Oil: A Citrusy Essential Oil With Well-Rounded Uses

Natural Remedies for the Prevention of Dry Eyes

Magnesium Deficiency Raises Your Risk of Many Chronic Ailments

Resveratrol supplementation improves arterial stiffness in type 2 diabetics

CoQ10's Potential Capabilities for Your Health

How Can Melatonin Benefit You?

Cloves: Boost Your Immune System the Sweet and Spicy Way

8 Chia Seed Recipes

Testosterone replacement therapy associated with improved urinary, sexual function

 
Print Page
Email Article

The relevance of sleep abnormalities to chronic inflammatory conditions

  [ 317 votes ]   [ 1 Comment ]
By Z Ranjbaran, et al. • www.ProHealth.com • April 20, 2007


Journal: Inflammation Research. 2007 Feb;56(2):51-57.

Authors and affiliations: Ranjbaran Z, Keefer L, Stepanski E, Farhadi A, Keshavarzian A. Section of Gastroenterology and Nutrition, Rush University Medical Center, Chicago, Illinois. [E-mail: ziba_ranjbaran@rush.edu ]

PMID: 17431741

Sleep is vital to health and quality of life while sleep abnormalities are associated with adverse health consequences. Nevertheless, sleep problems are not generally considered by clinicians in the management of chronic inflammatory conditions (CIC) such as asthma, rheumatoid arthritis, SLE [systemic lupus erythematosus] and IBD [inflammatory bowel disease].

To determine whether this practice is justified, we reviewed the literature on sleep and chronic inflammatory diseases, including effects of sleep on immune system and inflammation.

We found that a change in the sleep-wake cycle is often one of the first responses to acute inflammation and infection, and that the reciprocal effect of sleep on the immune system in acute states is often protective and restorative. For example, slow wave sleep can attenuate proinflammatory immune responses while sleep deprivation can aggravate those responses.

The role of sleep in CIC is not well explored. We found a substantial body of published evidence that sleep disturbances can: n Worsen the course of chronic inflammatory conditions, n Aggravate disease symptoms such as pain and fatigue, n And increase disease activity and lower quality of life.

The mechanism underlying these effects probably involves dysregulation of the immune system.

All this suggests that managing sleep disturbances should be considered as an important factor in the overall management of chronic inflammatory conditions.





Post a Comment

Featured Products From the ProHealth Store
Ultra ATP+, Double Strength Optimized Curcumin Longvida® Energy NADH™ 12.5mg


Article Comments Post a Comment

Sleep Deprivation
Posted by: Bluebrush
Apr 26, 2007
I have noticed the serious impact of sleep loss on my SLE and FM flares. I did not think about the flare causing the sleep problem, but it makes sense. It is a vicious cycle. I really don't know what to do. Various drugs given to me haven't worked and it seriously affects my health. Right now, I have been fighting constant flares: terrible pain, fatigue, fevers, hair loss, mouth sores, and sleep has been worse than ever. Of course, I take immune suppressants to control the most serious symptoms. I would love to learn how doctors successfully help us sleep! What have others done? Of course, I am raising 4 children alone, so I don't have much available time for some things like meditation (which used to help), but I'd appreciate whatever you all might be able to pass on.
Reply Reply
 
Optimized Curcumin Longvida with Omega-3

Featured Products

FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength

Natural Remedies

Are You Obtaining the Proper Enzymes? Are You Obtaining the Proper Enzymes?
A Hard-Working Molecule that May Help Ease Pain & Brighten Mood A Hard-Working Molecule that May Help Ease Pain & Brighten Mood
Stop Bacteria With Nature's Antibiotics Stop Bacteria With Nature's Antibiotics
Rejuvenating the Brain - How PQQ Helps Power Up Mental Processing Rejuvenating the Brain - How PQQ Helps Power Up Mental Processing
Physically and Mentally Exhausted? How to Restore Energy at Its Source Physically and Mentally Exhausted? How to Restore Energy at Its Source

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map