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Functioning in individuals with Chronic Fatigue Syndrome: Increased impairment with co-occurring Multiple Chemical Sensitivity and Fibromyalgia

  [ 399 votes ]   [ 2 Comments ]
By Leonard A Jason and Molly M Brown • www.ProHealth.com • June 2, 2007


Journal: Dynamic Medicine. 2007 May 31;6(1):6 [E-publication ahead of print] Note: This is an Open Access article. You may read the full text in PDF at http://www.dynamic-med.com/content/pdf/1476-5918-6-6.pdf.

Authors and affiliation: Brown MM, Jason LA. Affiliation: Department of Psychology, DePaul University, Center for Community Research, Chicago, Illinois, USA. [E-mail ljason@depaul.edu; mbrown59@depaul.edu ]

PMID: 17540028

Background: Chronic Fatigue Syndrome (CFS), Multiple Chemical Sensitivity (MCS), and Fibromyalgia (FM) commonly co-occur. Some propose that CFS, MCS, and FM are manifestations of the same illness based on high rates of co-occurrence and overlapping diagnostic criteria.

This study seeks to differentiate these diagnoses by comparing individuals with one or more illness on functioning, psychiatric comorbidity, coping style, and in vivo physical measures.

Methods: Participants included 114 men and women who met criteria for CFS. FM was diagnosed during a physical examination, and MCS was assessed using a questionnaire.

Participants were divided into four groups: CFS alone, CFS-MCS, CFS-FM, and CFS-MCS-FM. Self-report measures, a psychiatric interview, and in vivo physical measures were given.

Results:

  • 43.9% met criteria for CFS alone,
  • 23.7% met criteria for CFS-MCS,
  • 15.8% met criteria for CFS-FM,
  • 16.7% met criteria for CFS-MCS-FM.

The CFS-MCS-FM group was more disabled than the CFS alone group on measures of physical functioning, general health, and bodily pain. In vivo measures did not differ, but the CFS-MCS-FM group rated exertion higher than the CFS alone group.

Conclusions:

Individuals with CFS alone were the highest functioning group across several domains, such as disability, depression, and severity of symptoms.

Participants with three diagnoses experienced the greatest amount of disability.

While substantial co-occurrence of these illnesses was found, this study provides evidence that having more than one illness exacerbates one's disability beyond CFS alone.





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Article Comments Post a Comment

multiple impairments in FM/CFS/MCS
Posted by: JONSsis
Jun 13, 2007
To deduce the kind of information from such a small study group is not something to get excited about, but almost anyone with FM has been able to understand that the other conditions may be mixed up with the FM. Differentiation of FM with other conditions is really tough, especially for the physicians who really try to help their patients. It took several years for me to sort arthritic pain (OR) from FM, but the effort was worth it. I would very much like to see a larger study group, plus the inclusion of ANY other conditions that affect FM.
Reply Reply

PET SYMPTOMS AND HUMAN SYMPTOMS OF AUTO IMMUNE
Posted by: Mutley24
Jun 13, 2007
I HAVE HAD FM/CF FOR OVER 15 YEARS, ONLY LAST YEAR HAS IT BECOME UNBEARABLE. PAIN NEVER STOPS,VERY DIFFICULTY GETTING UP. QUESTION, ARE THERE ANY PET OWNERS WITH SAME SYMPTOMS? I HAVE HAD TWO DOGS IN THE LAST 15 YEARS. THE FIRST ONE DIED IN 2000. HE HAD IMMUNE MEDIATED POLY ARTHRITIS, IT IS AUTO IMMUNE SYSTEM ATTACKING ITSELF RESULTING IN PAINFUL JOINTS AND MUSCLES. NOW I HAVE ANOTHER DOG WHO HAS NOW DEVELOPED THE SAME THING. YOU WOULD THINK THAT WE ARE TWINS WITH TRYING TO GET UP. JUST A THOUGHT TO SEE IF ANY PET OWNERS HAVE SAME PET SYMPTOMS AS THEMSELVES.
Reply Reply
 
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