Activate Now
 
ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Patient Insights into the Design of Technology to Support a Strengths-Based Approach to Health Care.

SURVEY: Weight Management & Chronic Illness

Japanese green tea consumers have reduced risk of dementia

Do Nothing, Accomplish Everything! The Connection Between Breathing and Healing

Meet the ProHealth Editors

Best Herbs to Help With Insomnia

Nature Heals

Choline: Why You Should Eat Your Egg Yolks and Take Krill

Calcium, vitamin D supplementation associated improved stroke recovery

Acupressure reduced fatigue in breast cancer survivors

 
Print Page
Email Article

Cytokine patterns in Fibromyalgia and their correlation with clinical manifestations

  [ 153 votes ]   [ Discuss This Article ]
By L Bazzichi, et al. • www.ProHealth.com • June 6, 2007


Journal: Clinical and Experimental Rheumatology. 2007 Mar-Apr;25(2):225-30.

Authors and affiliation: Bazzichi L, Rossi A, Massimetti G, Giannaccini G, Giuliano T, De Feo F, Ciapparelli A, Dell'osso L, Bombardieri S. Department of Internal Medicine, Division of Rheumatology, University of Pisa, Pisa, Italy.

PMID: 17543146

Objective: To examine the possible role of the soluble factor in Fibromyalgia (FM) by studying the correlation of cytokine levels with the patients' clinical and psychiatric profile. [Cytokines are chemical signals released by many types of cells that accomplish cell-to-cell communication. They are made up of water-soluble proteins/glycoproteins, are particularly important in immune responses, and are involved in a variety of immunological, inflammatory, and infectious diseases.]

Methods: Eighty FM patients underwent clinical and psychiatric evaluations, and plasma levels of cytokines (IL-1, IL-6, IL-8, IL-10, TNF-alpha), aspecific markers of inflammation, rheumatoid factor (RF), anti-extractable nuclear antigen (ENA) antibodies, and anti-nuclear factor (FAN) were measured.

Results: Higher levels of IL-10, IL-8 and TNF-alpha were found in FM patients than in controls. Significant correlations between the biochemical parameters and clinical data were found.

Conclusion: The higher levels of cytokines found in FM patients suggest the presence of an inflammatory response system and highlight a parallel between the clinical symptoms and biochemical data. [Inflammatory response is inflammation responding to cellular injury by bacteria, toxins, trauma, or any other cause.] They support the hypothesis that cytokines may play a role in the clinical features of Fibromyalgia.

In addition, the similar cytokine patterns found in FM patients with different psychiatric profiles suggests that inflammatory response system impairment may play a specific role in the disease.





Post a Comment

Featured Products From the ProHealth Store
Optimized Curcumin Longvida® Vitamin D3 Extreme™ Energy NADH™ 12.5mg

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products


Article Comments



Be the first to comment on this article!

Post a Comment


 
Natural Pain Relief Supplements

Featured Products

Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium

Natural Remedies

Aching Muscles? Top 10 Nutrients to Take Back Your Life Aching Muscles? Top 10 Nutrients to Take Back Your Life
Strengthen Cell Function with Energy-Boosting Niagen Strengthen Cell Function with Energy-Boosting Niagen
Can Glycine + Amino Acids Be the Secret to Deep, Rejuvenating Sleep? Can Glycine + Amino Acids Be the Secret to Deep, Rejuvenating Sleep?
Breaking Through the Mental Fog Breaking Through the Mental Fog
Looking for Energy? Turn to Plants. Looking for Energy? Turn to Plants.

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE AND SAVE 15% NOW*
Be the first to know about new products, special discounts and the latest health news. *New subscribers only

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2016 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map