Activate Now
 
ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Patient Insights into the Design of Technology to Support a Strengths-Based Approach to Health Care.

SURVEY: Weight Management & Chronic Illness

Japanese green tea consumers have reduced risk of dementia

Do Nothing, Accomplish Everything! The Connection Between Breathing and Healing

Meet the ProHealth Editors

Best Herbs to Help With Insomnia

Choline: Why You Should Eat Your Egg Yolks and Take Krill

Calcium, vitamin D supplementation associated improved stroke recovery

Acupressure reduced fatigue in breast cancer survivors

More positive evidence for melatonin in breast cancer battle

 
Print Page
Email Article

Nutritional Supplements May Combat Muscle Loss

  [ 34 votes ]   [ Discuss This Article ]
www.ProHealth.com • August 27, 2002


HOUSTON - (Aug. 27, 2002) - Early indications show that nutritional supplements may lessen muscle atrophy brought on by space travel, prolonged bed confinement or immobility.

Through an NSBRI bed-rest study, an amino acid and carbohydrate supplement is being studied to determine its value as a nutritional countermeasure to muscle loss.

To study space travel's effect on muscles, Dr. Robert Wolfe of the University of Texas Medical Branch at Galveston enlisted healthy subjects to stay in bed 28 days during a National Space Biomedical Research Institute study.

"One cause of muscle atrophy in space is lack of muscular activity. That's why bed rest is a good model because it minimizes activity, and like astronauts, you lose muscle mass primarily in the legs," said co-investigator Dr. Arny Ferrando, a professor of surgery at UTMB and Shriners Hospital for Children in Galveston. "When muscles are inactive, as they are in space, they don't make new proteins. If muscle breakdown rates are the same, that means you lose muscle."

Researchers are attempting to increase protein synthesis rates with supplements of amino acids, which are the raw materials of protein. Participants received the supplements three times a day, and researchers compared the protein synthesis/breakdown rates and muscle mass before and after the bed-rest study. This data was compared to results from a control group that received a placebo drink instead of the supplements.

"Early results suggest that the amino acid supplement is able to maintain synthesis rates and body mass," Ferrando said.

During the study, subjects must remain in bed and can get up only briefly to use a bedside commode. They eat and bathe from their beds, and daily activities encompass watching television, reading books and using a bedside computer.

Midway through the study, researchers determine muscle mass and function by testing the subjects' strength and body composition.

They gather the most vital data, the protein synthesis and breakdown rates, by using stable isotope analysis. With the stable isotope technique, researchers attach a harmless tracer to specific amino acids that travel through the bloodstream. Then, they take blood samples to determine the amount of amino acids that enter and exit the leg.

"If 80 amino acids are coming into the artery and 60 are going out of the vein, we know that 20 were probably made into proteins in the muscle," said Dr. Douglas Paddon-Jones, also of UTMB and a co-investigator performing these studies. "We complete the muscle analysis by removing a small piece of muscle and determining how many amino acids have been incorporated into proteins. Over time, we can calculate the rate at which the synthesis and breakdown occurs."

Space conditions also elevate the body's level of the stress hormone cortisol, which increases the breakdown rate of proteins. "Under stress, the body breaks down proteins to make energy for survival," said Ferrando, a member of NSBRI's nutrition and fitness research team. "However, this process also causes muscle atrophy."

To study the supplement's effects on muscle loss due to elevated levels of cortisol, researchers infused the stress hormone into the participants' blood during the stable isotope tests. The researchers mimic the cortisol concentrations found during space flight, then determine protein synthesis and breakdown rates of the subjects taking the supplement and compare this to the rates of the control group.

Ferrando and Wolfe are also collaborating with other NSBRI researchers who use the subjects' body fluids to study changes in bone, immune function and cell damage induced by bed rest.

Findings from this research on nutritional supplements could benefit patients on Earth.

"Muscle atrophy is common in many populations: the elderly, kids with burns, patients in intensive care or people who have had major operations. We're looking at this phenomenon in terms of space flight, but the study has many other implications," Ferrando said.


The NSBRI's consortium members include Baylor College of Medicine, Brookhaven National Laboratory, Harvard Medical School, The Johns Hopkins University, Massachusetts Institute of Technology, Morehouse School of Medicine, Mount Sinai School of Medicine, Rice University, Texas A&M University, University of Arkansas for Medical Sciences, University of Pennsylvania Health System and University of Washington.



Post a Comment

Featured Products From the ProHealth Store
Ultra ATP+, Double Strength FibroSleep™ Energy NADH™ 12.5mg

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products


Article Comments



Be the first to comment on this article!

Post a Comment


 
Natural Pain Relief Supplements

Featured Products

Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium

Natural Remedies

Fight Inflammation and Promote Cognitive Health with High-OPC Grape Seed Fight Inflammation and Promote Cognitive Health with High-OPC Grape Seed
Probiotic Mint Promotes Healthy Gums & Teeth, Freshens Breath and Whitens Teeth Probiotic Mint Promotes Healthy Gums & Teeth, Freshens Breath and Whitens Teeth
Herbal Rescue for High Blood Sugar Herbal Rescue for High Blood Sugar
Enhance Eyelashes Naturally Enhance Eyelashes Naturally
Strontium - The Missing Mineral for Strong Bones Strontium - The Missing Mineral for Strong Bones

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE AND SAVE 15% NOW*
Be the first to know about new products, special discounts and the latest health news. *New subscribers only

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2016 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map