ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

How Can You Benefit From Vitamin B12?

Discover Why Ashwagandha Can Be Used for Stress and Anxiety

Calorie restriction promotes longevity through effects on mitochondrial network

Higher resveratrol dose linked to lower glucose levels in type 2 diabetics

Tryptophan's Possible Effects for Your Health

What Is Bitter Orange?

Black Tea Is Great for Your Gut

Drug can dramatically reduce weight of people with obesity

Ashwagandha Helps Hormones - Aids Arthritis

New Finding: Broccoli Helps Heal Leaky Gut

 
Print Page
Email Article

Low grade inflammation and arterial wave reflection in patients with Chronic Fatigue Syndrome – Source: Clinical Science (London), Nov 21, 2007

  [ 26 votes ]   [ Discuss This Article ]
By Vance A Spence, PhD, et al. • www.ProHealth.com • November 23, 2007


[Note: Arterial wave reflection is an indicator of arterial stiffness.]

Some of the symptoms reported by people with Chronic Fatigue Syndrome (CFS) are associated with various cardiovascular phenomena. Markers of cardiovascular risk, including inflammation and oxidative stress, have been demonstrated in some CFS patients but little is known about the relationship of these and prognostic indicators of cardiovascular risk in this patient group.

We sought to investigate the relationship between inflammation and oxidative stress and augmentation index, a measure of arterial stiffness, in 41 well characterized CFS patients and in 30 healthy subjects.

The augmentation index, normalized for a heart rate of 75 beats per minute (AIx@75), was significantly greater in CFS patients than in control subjects (22.5 +/- 1.7 versus 13.3 +/- 2.3%, P=0.002). CFS patients also had significantly increased levels of C-reactive protein (2.58 +/- 2.91 versus 1.07 +/- 2.16 g/mL, P<0.01) and 8-iso-prostaglandin F 2alpha isoprostanes (470.7 +/- 250.9 versus 331.1 +/- 97.6 pg/mL, P<0.005).

In CFS patients, AIx@75 significantly correlated with log C-reactive protein (r=0.507, P=0.001), isoprostanes (r=0.366, P=0.026), oxidized LDL (r=0.333, P=0.039) and systolic blood pressure (r=0.371, P=0.017).

In a stepwise multiple regression model, (including systolic and diastolic blood pressure, body mass index, C-reactive protein, TNFalpha, IL-1, oxidised LDL, HDL cholesterol levels, isoprostanes, age and gender), AIx@75 was independently associated with log CRP (beta=0.385, P=0.006), age (beta=0.363, P=0.022), and female gender (beta=0.302, P=0.03) in CFS patients.

The combination of increased arterial wave reflection, inflammation and oxidative stress may result in an increased risk of future cardiovascular events. Assessment of arterial wave reflection might be useful for determining cardiovascular risk in this patient group.

Source: Clinical Science (London) Nov 21 2007; [E-pub ahead of print] PMID: 18031285, by Spence VA, Kennedy G, Belch JJ, Hill A, Khan F. Institute of Cardiovascular Research, University of Dundee Medical School, Dundee, Scotland, UK.





Post a Comment

Featured Products From the ProHealth Store
Ultra ATP+, Double Strength Vitamin D3 Extreme™ Mitochondria Ignite™ with NT Factor®


Article Comments



Be the first to comment on this article!

Post a Comment


 
Optimized Curcumin Longvida with Omega-3

Featured Products

FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils

Natural Remedies

The Super Antioxidant for Brain, Joint and Heart Health The Super Antioxidant for Brain, Joint and Heart Health
Bone Broth Benefits for Digestion, Arthritis and Cellulite Bone Broth Benefits for Digestion, Arthritis and Cellulite
Quercetin: Natural Support for Allergy & Inflammation Relief and More Quercetin: Natural Support for Allergy & Inflammation Relief and More
Complete and Natural Menopause Relief Complete and Natural Menopause Relief
A Hard-Working Molecule that May Help Ease Pain & Brighten Mood A Hard-Working Molecule that May Help Ease Pain & Brighten Mood

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map