ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Prevent Or Reverse Diabetes: An Amazing Herbal Intervention

Exercise and Vitamin D Better Together for Heart Health

VIDEO: Essential Oils for Weight Loss

Can Ginkgo Give Your Brain a Boost?

Can Valerian Root Help You Sleep Better?

Fighting Statin-Induced Diabetes with CoQ10

Eight servings of veggies a day is clearly best for the heart

The Many Wonders of Calming Sandalwood Oil

Curcumin — A Novel Treatment Alternative for Depression

How Glycation Accelerates Aging

 
Print Page
Email Article

Restless legs syndrome as side effect of second generation antidepressants – Source: Journal of Psychiatric Research, May 9, 2008

  [ 38 votes ]   [ 2 Comments ]
By Klaus G. Rottach, et al. • www.ProHealth.com • May 15, 2008


Although of clinical interest, the question is still not fully answered whether antidepressants (AD) can cause or exacerbate restless legs syndrome (RLS). The literature provides contradictory information.

This study addresses this problem for the class of second generation AD. In four neurological offices, all patients treated for the first time with an AD were prospectively observed with regard to the question of whether RLS occurred, or pre-existing RLS worsened as a result of the medication.

Because initial treatment in the participating offices is mainly executed with "modern" selective AD, the study was restricted to these drugs: fluoxetine, paroxetine, citalopram, sertraline, escitalopram, venlafaxine, duloxetine, reboxetine, and mirtazapine.

  • In 9% of patients, RLS was recorded as a side effect related to the administration of AD. The frequency of this side effect varied among the drugs.
  • The problem is most pronounced with mirtazapine [most common brand name RemeronR] provoking or deteriorating RLS in 28% of patients.
  • By contrast, no case occurred during use of reboxetine [brand names EdronaxR and others].
  • As for the other AD, the rate of newly occurred and deteriorated RLS ranged from 5% to 10%.
  • Typically, RLS occurred during the initial days of treatment.

Source: Journal of Psychiatric Research, May 9, 2008. [Epub ahead of print] PMID: 18468624, by Rottach KG, Schaner BM, Kirch MH, Zivotofsky AZ, Teufel LM, Gallwitz T, Messer T. Gonda Brain Research Center, Bar Ilan University, Ramt Gan, Israel; Bezirkskrankenhaus Augsburg, Clinic for Psychiatry and Psychotherapy, Augsburg, Germany.





Post a Comment

Featured Products From the ProHealth Store
Ultra ATP+, Double Strength Ultra EPA  - Fish Oil Optimized Curcumin Longvida®

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products


Article Comments Post a Comment

Title of article
Posted by: bettemabry
May 21, 2008
The title of this article is misleading. When I read the title, I read that RLS is a definite side effect of antidepressants. According to the article, it is a questionable effect and if it is, the effect is not highly correlated. Much of the time I do not have time to read articles completely, as I am sure others have the same situation. This is what causes misconceptions and/or rumors about medical matters.
Reply Reply

 
I agree
Posted by: Musyn
May 21, 2008
I agree completely, bettemabry. I read and reread the piece, thinking I had intermittent brainfog that was preventing me from seeing which antidepressants gave RLS as a side effect. Because, as usual, I figured it was me missing something obvious. Maybe it's a typo and there should have been a question mark after the title. "Restless legs syndrome as a side effect of second generation antidepressants?"

 

 
NAD+ Ignite with Niagen

Featured Products

FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium

Natural Remedies

Fighting Fatigue with Ground-breaking French Oak Wood Extract Fighting Fatigue with Ground-breaking French Oak Wood Extract
Eating Fat is Good... Maybe... Could Be... Sometimes Eating Fat is Good... Maybe... Could Be... Sometimes
Relief for Dry, Itchy Skin Caused by Fibromyalgia Relief for Dry, Itchy Skin Caused by Fibromyalgia
Everything You Always Wanted to Know About Sleep But Were Too Tired to Ask Everything You Always Wanted to Know About Sleep But Were Too Tired to Ask
Bone Broth Benefits for Digestion, Arthritis and Cellulite Bone Broth Benefits for Digestion, Arthritis and Cellulite

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map