ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Magnesium Protects Against Stroke, Heart Disease and Diabetes

Astaxanthin Is a Longevity Promoter

Meta-analysis links vitamin D deficiency with increased risk of mortality during 10.5 year median pe...

Prevent Or Reverse Diabetes: An Amazing Herbal Intervention

Exercise and Vitamin D Better Together for Heart Health

VIDEO: Essential Oils for Weight Loss

Can Valerian Root Help You Sleep Better?

Eight servings of veggies a day is clearly best for the heart

The Many Wonders of Calming Sandalwood Oil

Fighting Statin-Induced Diabetes with CoQ10

 
Print Page
Email Article

Probiotic intervention has strain-specific anti-inflammatory effects in healthy adults – Source: World Journal of Gastroenterology, April 7, 2008

  [ 54 votes ]   [ Discuss This Article ]
By RA Kekkonen, et al. • www.ProHealth.com • May 22, 2008


Aim: To evaluate the effects of three potentially anti-inflammatory probiotic bacteria from three different genera on immune variables in healthy adults in a clinical setting based on previous in vitro characterization of cytokine responses.

Methods: A total of 62 volunteers participated in this randomized, double-blind and placebo-controlled parallel group intervention study.

The volunteers were randomized to receive a milk-based drink containing either:

  • Lactobacillus rhamnosus GG (LGG),
  • Bifidobacterium animalis ssp. lactis Bb12 (Bb12), or
  • Propionibacterium freudenreichii ssp. shermanii JS (PJS)
  • Or a placebo drink, for 3 weeks.

Venous blood and saliva samples were taken at baseline and on days 1, 7 and 21. Fecal samples were collected at baseline and at the end of intervention.

Results:

  • The serum hsCRP expressed as the median AUC0-21 (minus baseline) was 0.018 mg/L in the placebo group, -0.240 mg/L in the LGG group, 0.090 mg/L in the Bb12 group and -0.085 mg/L in the PJS group (P = 0.014). [CRP (C-reactive protein) is an indicator of inflammation, measured by hsCRP (high sensitivity C-reactive protein) testing.]
  • In vitro production of TNF-alpha from in vitro cultured peripheral blood mononuclear cells (PBMC) was significantly lower in subjects receiving Lactobacillus rhamnosus (LGG) vs placebo. [TNF-alpha (Tumor necrosis factor-alpha) is a cytokine or ‘signaling protein’ that stimulates systemic inflammation.]
  • IL-2 production from PBMC in the Bifidobacterium animalis (Bb12) group was significantly lower compared with the other groups. [IL-2 (Interleukin 2) is a type of cytokine that makes infection-fighting cells multiply and mature.]

Conclusion: In conclusion, probiotic bacteria have strain-specific anti-inflammatory effects in healthy adults.

Source: World Journal of Gastroenterology, April 7, 2008. PMID , by Kekkonen RA, Lummela N, Karjalainen H, Latvala S, Tynkkynen S, Jarvenpaa S, Kautiainen H, Julkunen I, Vapaatalo H, Korpela R. Institute of Biomedicine, Pharmacology, University of Helsinki, Helsinki, Finland. [E-mail: riitta.korpela@valio.fi]





Post a Comment

Featured Products From the ProHealth Store
Ultra EPA  - Fish Oil Mitochondria Ignite™ with NT Factor® FibroSleep™

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products


Article Comments



Be the first to comment on this article!

Post a Comment


 
NAD+ Ignite with Niagen

Featured Products

Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function

Natural Remedies

Herbal Inflammation Management for Whole Body Health Herbal Inflammation Management for Whole Body Health
Block food Cravings At Their Molecular Root Block food Cravings At Their Molecular Root
Aches and Pains? A Simple Solution You'll Love Aches and Pains? A Simple Solution You'll Love
Soothe, Heal and Regulate Your Digestive System with Nutrient-Rich Aloe Vera Soothe, Heal and Regulate Your Digestive System with Nutrient-Rich Aloe Vera
Natural Support for Mood, Sleep and Mental Focus? L-theanine Natural Support for Mood, Sleep and Mental Focus? L-theanine

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map